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JARROW Methyl B-12 & Methyl Folate + P5P (B6) constitutes a well-thought-out supplement in the composition of which there are active forms of vitamins from group B. The composition composed in such a way constitutes great support for the organism, as a range of factors, such as age or stress negatively influence the process of activation of many vitamins in the liver, thanks to which we often may suffer from deficits of these vitamin in the organism. The combination of all three active forms of the vitamin in one capsule ensures an effective way to normalize the level of these active compounds in the organism.
Vitamin B6 in the form of pyridoxal 5'-phosphate, after being absorbed in the intestines immediately fulfills its function. Similarly to other vitamins from this group, it takes part in the functioning of many enzymes important for life. Moreover, it plays the function of prosthetic group of enzymes, which are responsible for amino acid metabolism.
Its positive influence on the synthesis of such neurotransmitters as dopamine, serotonin and glucocorticoids has been confirmed. It constitutes a methyl group donor for homocysteine, by which it converts it to methionine, thanks to which it lowers its negative influence on blood vessels.
It supports hematopoietic system, thanks to the participation in the production of erythrocytes, which constitute one of the more important components of blood
Moreover, it helps to absorb in the intestines such elements as magnesium and regulates the level of sodium and potassium, thanks to which it influences maintaining proper electric potential in the nervous system.
Vitamin B9 in the form of methylfolate contains a very important methyl group in a molecule, thanks to which after the introduction to the organism, it does not have to be activated. As the remaining vitamins from this group, it has the ability to dissolve in water, thanks to which, it is practically impossible to overdose it, as its excess is quickly eliminated with urine. Among many people improper functioning of MTHFR enzyme has been noticed, the task of which is transforming inactive forms of vitamins from the group B to the forms demonstrating positive effect on the functioning of many enzymes and systems.
It shows important influence on the proper functioning of the nervous system, thanks to the fact that it supports the synthesis of such neurotransmitters as – serotonin, dopamine, adrenaline and melatonin. It positively influences nervous system thanks to the ability to cross blood-brain barrier.
Similarly to other vitamins from this group, it has the ability to decrease homocysteine level to its physiologically proper level, thanks to which it inhibits its degenerative influence on blood vessels, both in the central and peripheral nervous system.
Vitamin B12 in the methylated form – methylcobalamin, constitutes a highly assimilable supplement. Moreover, such form is fully active, thanks to which, after the absorption in the intestines, it will immediately influence the positive functions of supplementation. Moreover, the vitamin in this form has the ability to cross blood-brain barrier, thanks to which it has a positive influence on the organism and the nervous system.
Methylcobalamin demonstrates many pro-health properties. One of the more important ones is lowering the level of homocysteine, thanks to its conversion to harmless methionine. Homocysteine is an amino acid containing sulfur compounds, which is considered to be one of the more dangerous factors causing atherosclerosis, which has a destructive effect on blood vessels in the human organism. Beneficial influence of methylated form of vitamin B12 has been also noticed thanks to its positive influence on the production of erythrocytes.
Positive influence of methylcobalamin on the functioning of the nervous system has also been proven. It counteracts the process of demineralization, which develops with age, which is responsible for a range of diseases related to the nervous system. Myelin sheath constitutes a form of isolation for neurons appearing side by side. Such an effect of the vitamin is possible thanks to activating methionine synthase. Moreover, this enzyme is used to synthesize nitrogen bases, which are important components of nucleic acids. Glutamate is a neurotransmitter fulfilling an important function in the nervous system, but in certain situations, its expression is too high, thanks to which it may excessively stimulate our nervous system, damaging it. Methylcobalamin shows antagonistic effect to excessively strong stimulation by glutamate.
The supplement JARROW Methyl B-12 & Methyl Folate + P5P (B6) is addressed to everybody, because of its wide scope of factors important to homeostasis. Moreover, it the current times, food is not as rich in nutrients as in the past, therefore it is worth taking care about the proper level of vitamins and microelements in our organism to enjoy good state of health as long as possible.
| per 1 lozenge | amount | %DV |
|---|---|---|
| Vitamin B6 (as pyridoxal 5-phosphate) | 1.5 mg | 75% |
| Folate (as Quatrefolic (6S)-5-methyltetrahydrofolic acid glucosamine salt) | 400 mcg | 100% |
| Vitamin B12 (as methylcobalamin) | 1,000 mcg | 16,670% |
Xylitol, cellulose, stearic acid (vegetable source), natural lemon flavor, citric acid, magnesium stearate (vegetable source), silicon dioxide and rebiana (stevia extract).
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Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
Quatrefolic is the glucosamine salt of (6S)-5-methyltetrahydrofolate and also an active form of folic acid. It is an innovative nutrient (fourth generation folate) which is well soluble in water and thus absorbed effectively by the body. As an organic compound ranked among B vitamins, it is necessary for normal functioning at the cellular level.
Adding folates to a diet is recommended especially to pregnant and lactating women. These compounds may contribute to healthy foetal development. According to studies, their intake may reduce the incidence of pregnancy complications.
Some sources report that folate supplementation supports cardiovascular function (blood production) and contribute to healthy immune function.
Quatrefolic may affect the metabolism of homocysteine whose levels increase in the body over time. Adding it to a diet may thus prevent the development of dementia and maintain healthy cognitive functions which is vital to adults, especially the elderly.
Salt (sodium chloride, or table salt), natural source of electrolytes (chlorine and potassium), regulating water and electrolyte and acid-base balance of the body, affecting the nervous system and blood pressure. Sodium is an essential element for the proper growth. The proper dose of salt prevents overheating of the body and solar stroke. It provides the proper functioning of muscles and nerves the body. Chlorine in combination with sodium, is involved in the digestive process and maintains acid-base balance in the body, as antitoxin removes toxic products of metabolism in the liver. Salt is a flavour component and preservative of many foods, nutritional supplements and mixtures of electrolytes, available at www.muscle-zone.pl
Dosage: no specific standards of consumption, used so as to provide sufficient amount of electrolytes to the body (sodium and chloride).
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
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