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Jarrow Formulas TMG Crystals Powder is a dietary supplement which consists of trimethylglycine, which is also known as anhydrous betaine or TMG. It is an important donor molecule which provides three methyl groups.
Trimethylglycine – is an amino acid which is contained in plants, such as sugar beets, and in the human body system. It takes part in the liver function and cell reproduction. It is useful in the production of creatine.
TMG / methylation processes
TMG delivers three methyl groups to the body system. They are necessary for numerous biochemical reactions in the human body system.
Methylation is a process which occurs in each cell. Thanks to it the methyl groups are synthesized (they are essential for other reactions which occur in the body system). It plays a significant role in the protection of DNA, the mechanisms of detoxification, lipid metabolism and the production of s-adenosylmethionine. These transformations have a positive impact on the production of neurotransmitters – dopamine and serotonin.
TMG plays an important role in the conversion of harmful homocysteine into "friendlier" methionine
Trimethylglycine is a great addition for the treatment with methylfolate, particularly in people with a MTHFR genetic mutation. TMG bypasses the gene mutation and directly lowers homocysteine levels, so you can use lower doses of methylated folate and active forms of vitamins B.
TMG / homocysteine
An important function of anhydrous betaine is a reduction of homocysteine levels. It is a toxic substance, which is produced mainly during the digestion of meat. Its excess, this means hyperhomocysteinemia, leads to atherosclerotic changes, heart attack, stroke and thromboembolic disorders. That is why it is important to maintain healthy levels of homocysteine in the body system.
Betaine supports the proper liver functions (through its detoxification) and stomach functions (by restoring an adequate level of digestive juices).
TMG / creatine synthesis
Trimethylglycine takes also part in the synthesis of glycocyamine, which is the direct precursor to creatine and is essential to its synthesis at each stage. Creatine is responsible for moving all acid radicals and also provides fatty acids into the mitochondria, where they can be burnt. It also increases the synthesis of muscle proteins
TMG / antiestrogen
We may use betaine as an antiestrogen which inhibits the development of adipocites (fat cells), which are responsible for the development of lipomastia – the accumulation of fat around the nipples and the growth of their glandular tissue, which makes it difficult to obtain a sport figure.
TMG / for athletes
The studies show that TMG positively affects exercise capacity and can prevent the accumulation of new fat tissue. Trimethylglycine allows for faster muscle oxygenation, which results in an increase in exercise intensity. This leads to a greater involvement of the muscle fibers, which ultimately stimulates muscle to increased growth – this all results in greater muscle mass!
To sum it all up, Jarrow Formulas TMG Crystals Powder is a product recommended for active people and athletes, as it is a very effective agent which improves the results. It is also recommended for people with impaired methylation and higher homocysteine levels (including the MTHFR mutation).
The recommended dose (650 mg) is enough to bring the effect of reducing the level of toxic homocysteine. It was noted that in the case of 500 mg per day there was a beneficial effect on stabilizing the level of this amino acid.
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Glycine is belongs to 22 essential amino acids (synthesized within the body) constructing proteins, and non-protein component of enzymes i.e. heme. It is a inhibiting neurotransmitter allowing for improvement in sleep comfort even at a dose of 3 g at bedtime. Glycine (as arginine) is a precursor of creatine. It is essential for the synthesis of a strong antioxidant - removing free radicals out of the body - glutathione. It is cholagogic and cholepoiteic. By interfering with the synthesis of growth hormone, accelerates the biological recovery of an organism. Naturally present in foods of plant and animal origin. In the sports supplementation is a component creatine stacks, amino acid supplements, protein supplements based on natural ingredients and carbohydrate and protein.
Betaine (N, N, N-trimethylglycine, the TMG) is methyl glycine derivative participating in the conversion of homocysteine to methionine. It is present in food of plant origin and produced by the body in the liver or kidneys. The medicine uses it in the treatment of gastrointestinal and digestive disorders and hyperhomocysteinemia. In the supplements that increase the level of homocysteine used together with glycocyamine, indirectly influences the endogenous synthesis of creatine. There is no mono-preparation supplement containing betaine. Available in creatine stacks and the detoxicating supplements.
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