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NOW L-Lysine 500 mg is a high-quality monopreparation designed for making up L-lysine deficiencies in your diet. By providing a well-absorbed form of amino acid, it involves effectively in the development and formation of body structures, especially the skeleton, supports a healthy cardiovascular system, improves the immune response and promotes the body’s detoxification processes. It is recommended for diets poor in animal products and the body weakened and emaciated by strenuous physical activity.
L-lysine – known as 2,6-Diaminohexanoic acid or shortened as Lys or K, well soluble in water, a nitrogen chemical compound from a group of amino acids. In terms of its structure, it belongs to a subgroup of basic amino acids. Since it needs to be provided with food to ensure proper functioning of the human body, it is an essential (indispensable) amino acid. It is an important building block for proteins, classified as a proteinogenic compound. Due to its ability to convert into ketone bodies, it is categorised as a ketogenic compound. L-lysine was isolated for the first time in 1889 from milk proteins, specifically casein. Its most rich sources are: gelatine, dairy products, little processed meat products, eggs, many legumes or cocoa. Cereals, including wheat and corn but excluding wheat germ, contains naturally little amounts of this amino acid and is thus a limiting amino acid. According to different sources, the daily requirements of the average adult for L-lysine is 30-38 mg/kg per body weight, which is about 3 g. This is the highest demand for essential proteolytic amino acid just after L-leucine.
Properties of L-lysine
It supports the growth, development and maintenance of body structures.
As a consitutent of many proteins, especially collagen and elastin, it is a building block for many structures which are “framework” for the body after its conversion into hydroxylysine. Since it forms collagen, L-lysine is critical to maintaining healthy joints, skin and bones. In addition, by increasing intestinal calcium absorption, it decreases calcium urine excretion and promotes crosslinking of this element with collagen in bones. As a result, it helps maintain a strong skeleton.
The impact on proper energy balance
As a ketogenic compound which is a substrate for producing ketone bodies, it helps generate alternative energy during energy deficits. As a precursor of L-carnitine, it is involved in the transport of long chain fatty acids into mitochondria which allows for energy production processes involving fats. Increased daily L-lysine intake reduces unwanted protein glycation in the event of prolonged elevated blood sugar levels.
Improved immune response
It ensures proper immune response as a necessary component of proteins involved in the production of antibodies and specific immune enzymes and by mobilising the immune system. When lysine intake is not sufficient, the body is more prone to infections.
Reduced recurrence of herpes
By competing with L-arginine, which is an essential nutrient for herpes simplex virus (HSV), it reduces the activity of this virus, prevents its recurrence and shortens duration of the infection. The effects depend from an individual’s predisposition. To exceed 165 μM/L in serum, 1-3 g of the amino acid daily seems to be an effective dose.
Supported detoxification processes
L-carnitine, a derivative of L-lysine, protectes organelles from toxic concentration of compounds by transferring short-chain fatty acids away from mitochondria. What is more, L-lysine binds lead and facilitates its excretion, thereby decreasing its accummulation in the body.
It helps maintain strong bones by taking part in the formation of dense structures of collagen crosslinking calcium and improving calcium bioavailability from the digestive system while decreasing its excretion through the urine.
Support for a healthy cardiovascular system
As a part of vessel structures, it ensures their proper integrity, immunity and thus elasticity, necessary for preserving its functionality. As a precursor of L-carnitine, it aids in the transport of fatty acids to sites of their burning which improves the lipid profile. By limiting glycation processes in the event of prolonged elevated blood sugar levels, it supports a healthy cardiovascular system.
Reduced unnecessary fearfulness
As an partial antagonist of serotonin receptor, it reduces unnecessary fearfulness. It relieves anxiety and helps react appropriately to stress.
Speeds up wound healing
L-lysine is a component of collagen, contributes to speeding up cell regeneration and promotes angiogenesis of formed cells. Because of that, it supports wound healing while reducing scar and deformation in the damaged area.
Effects of L-lysine deficiency
The human body has a great ability to store L-lysine in intracellular fluid of muscle tissue. This shows big storage potential of the amino acid and confirms its enormous importance for healthy functioning of the whole body. L-lysine deficiencies in diet and hence its prolonged deficits may lead to: chronic fatigue, dizziness, irritability, nausea, ocular hyperaemia, increased hair loss, anaemia, anorexia, impaired growth and reproductive disorders. They are observed most frequently in individuals avoiding animal products and exhausting their body, e.g. by strenuous physical activity, which is one of the first symptoms of increased susceptibility to infections.
The most popular and acceptable chemical form of supplemented L-lysine is lysine hydrochloride which is effectively used by the body. Its action equals the amino acid derived from traditional food. Enriching your diet with L-lysine in the form of monopreparation is commonly believed to be very safe. Nevertheless, too high amount of the amino acid (10-15 g daily) may cause diarrhoea and stomach cramps which disappear after discontinuing supplementation. It is worth remembering that L-lysine competes with L-arginine for intestinal and second absorption in kidneys, as well as its transfer from plasma membrane to cells. In some extreme cases, this may impair the action of L-arginine. Because of that, it is essential to choose a reasonable, daily dose of the amino acid. L-lysine supplementation is recommended mainly to individuals whose diet is poor in animal products or whose body was weakened or emaciated due to different reasons.
NOW L-Lysine 500 mg is a food product supplementing your diet with L-lysine. By providing building blocks of many proteins, including collagen and elastin, it promotes the development of cartilages, joints, skin and muscles. As a precursor of alternative sources of energy and L-carnitine, it contributes to normal energy balance. Since it is essential to immune function and improves the effectiveness of detoxification processes, it helps maintain a healthy body. It is also vital to proper functioning of vessels and prevents glycation, it supports cardiovascular function. In addition, it prevents osteoporosis and herpes, speeds up wound healing and reduces fearfulness. An encapsulated form of L-lysine hydrochloride which is easy to swallow ensures high absorption of the amino acid, comparable to the amino acid derived from traditional food. It is recommended especially to individuals whose diet is poor in animal products and are exhausted and prone to infections.
To reduce herpes symptoms, it is recommended to take 2 g of lysine (4 tablets) daily with a meal, divided into smaller doses.
Lysine should be used by individuals with calcium deficiency. When lysine is administered together with calcium, it can promote calcium absorption.
Now Foods is a company with years of experience in the industry that offers a wide range of nutrients and dietary supplements. Brand is known for its high-quality products designed for hair and nails and supplements supporting the immune system. The offer includes the antioxidant supplements, antibacterial supplements, reducing appetite supplements, products supporting the reduction of body fat and improving digestion. All products are made from natural ingredients.
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Lysine belongs to the group of 9 essential amino acids delivered into the body from outside (with food or as a supplement) .It is a building substance of protein (the muscle protein). It is available in food of animal origin (meat, dairy products) and vegetable (legumes). It plays an important role in many physiological processes (absorption of calcium, production of enzymes, hormones and antibodies), and arginine is a component of supplements that increase the synthesis of growth hormone (HGH stimulators). In the form of hydroxylysine (a component of collagen) recommended for the treatment of sports injuries, and prevention. In the case of stress and excessive physical and psychological overloads, it is recommended due to the function of lowering cortisol levels. Also it applies in medicine, in the treatment of anxiety and herpes. The share of lysine intake of daily doses of amino acids should not exceed 5.1%. Available for purchase at www.muscle-zone.pl.
In the processes of digestion of protein matter, as a result of decarboxylation of lysine, may be converted into cadaverine (biogenic amine) having a strong toxicity.
Dosage: the lack of a well-defined standard daily intake of lysine. The supplementation dosages regularly used: with arginine 500 mg - 2g (before bedtime) pre- and post-workout optionally with other amino acids.
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