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5-HTP Time Release 5-HTP Time Release 200mg 30 tab.
21.10 $

5-HTP Time Release 200mg 30 tab.

Servings: 200mg 30 tab.

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21.10 $With VAT
0.70 $ / serving

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  • Supports depression treatment
  • Supports weight control
  • Reduces the production of serotonin
  • Stabilizes mood
  • Helps in insomnia treatment
  • Crosses the blood-brain barrier

Natrol, 5-HTP TR, Time Release is a dietary supplement containing a natural precursor to serotonin, 5-HTP (5-hydroxytryptophan) extracted from Griffonia simplicifolia plant. The product reduces the difficulties in falling asleep and allows you to maintain a healthy and efficient sleep, and moreover it relieves depressive symptoms and may support better control of body weight.

The product is recommended for people who, due to serotonin deficiency, have problems with sleeping, weight control and mood deterioration. Moreover, the product is also recommended to support depression treatment and to relieve the symptoms of premenstrual syndrome.

5-HTP (5-hydroxytryptophan) is a natural precursor to serotonin, which not only contributes to the synthesis of serotonin itself, but also stimulates the production of other neurotransmitters, such as dopamine, melatonin, noradrenaline and adrenocorticotropic hormone (ACTH). What is important, 5-HTP acts both peripherally and centrally.

Symptoms of serotonin deficiency
The causes of reduced serotonin levels in the body system may be different. First of all, they can be associated with impairment of the central functions, which results in depression, lower mood, aggression, eating disorders (lack of satiety, increased craving for meals rich in carbohydrates, and consequently overweight), sleeping disorders and memory deterioration. Another cause are somatic disorders, whose symptoms include, among others: irritable bowel syndrome (IBS), scoliosis, decrease in the activity of the immune system and fibromyalgia. There are also mixed signs in the form of migraine.

Increase in the secretion of “sleep hormone”
Serotonin is synthesized from tryptophan and plays a role of a precursor to melatonin. Melatonin is a hormone responsible for regulating circadian rhythms, which is an extremely important element influencing the functioning of the biological clock. For this reason, the serotonin deficiency can contribute to low levels of melatonin, which may result in sleeping disorders. Scientific studies have confirmed that 5-HTP has a positive influence on the quality of sleep; it reduces the time of falling asleep and facilitates waking up early.

Antidepressant properties
In the scientific research, it has been observed that 5-HTP has a beneficial influence on the health of people with depression. This compound counteracts panic attacks and relieves symptoms of depression. Its activity was compared to the actions of antidepressants and, in contrary to them, it caused no side effects. Moreover, 5-HTP was very effective in the case of bipolar disorder among people in whom the drug therapy did not give the desired result.

Relieving symptoms of PMDD
PMDD is premenstrual dysphoric disorder. This is one of the forms of premenstrual syndrome, which affects many women, and its symptoms are more intense and more persistent. It has been demonstrated that 5-HTP reduces depressive symptoms associated with PMDD, reduces mood swings, helps to keep the emotional balance, so that it makes it easier to survive these difficult days.

5-HTP versus eating disorders
Serotonin is a neurotransmitter which is responsible for controlling weight. Low levels of serotonin in the hypothalamus result in severe impairments whose symptom is i.a. a desire to binge. This is because in the hypothalamus a substance is produced, which is a neurohormone responsible for increase in appetite, MCH (melanin concentrating hormone), whose action together with a low concentration of serotonin leads to an increase in hunger and overeating, mostly of carbohydrate meals.

Scientific studies have demonstrated that regular supplementation with 5-HTP helped to reduce the incidence of nocturnal binge; it reduced the calorie intake from carbohydrates and led to a decrease in appetite, which resulted in better control of weight.

To sum it all up, Natrol, 5-HTP TR, Time Release is a dietary supplement that allows for the appropriate level of relaxation during sleep and the acceleration of falling asleep. Insomnia can lead to a reduction in concentration and memory, fatigue and mood deterioration, which adversely affects the quality of life, so it is worth to apply this natural substance and ensure adequate sleep hygiene. Moreover, the product has additional benefits in the form of mood stabilization and control of appetite. 

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Container size: 30 tabletsServing size: 1 tabletServings per container: 30
per 1 tabletamount%DV
Calcium (as Dibasic Calcium Phosphate)55 mg6%
5-HTP (5-Hydroxytryptophan)(derived from Griffonia simplicifolia)(seed)200 mg*

Other ingrednients

Dibasic Calcium Phosphate, Cellulose, Hypromellose, Stearic Acid, Silica, Magnesium Stearate, Methylcellulose, Glycerin

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Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess result
ing from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications
are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)



Tryptophan is one of the nine essential amino acids that require high protein food consumption, mono-preparation supplements tryptophan, an amino acid type and EAA-day nutrients and protein, which is essential in the process of protein synthesis. A derivative of 5-HTP in the decarboxylation is a precursor of serotonin ((tissue hormone having an effect on blood pressure and peristalsis), and the subsequent processes of melatonin (the hormone sleep). It is used for synthesis of nicotinic acid (niacin, known as vitamin PP). The due to the appetite suppressant is also used in certain weight loss formulations.
Even a small deficiency is dangerous for the course of many physiological processes, can cause the nervous system deterioration of mood, insomnia, and disturbances in the digestive process. Tryptophan deficiency in the long term leads to depression and neurological disorders.
Mono-preparation supplements of tryptophan are recommended as a means of reducing the stress and reducing the feeling of insomnia. A part of the nutritional supplements type of EAA and all-day aminoacids, it is a valuable component of protein supplements. Available in store
Doses recommended in supplementation: 500 - 2000 mg at bedtime, alternatively 500 - 1000 mg before meals.

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