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Hi-Tech Estrogenex 2nd Generation is an advanced preparation focused on optimizing testosterone secretion. Its main mechanism of operation is based on inhibiting aromatase, which converts male sex hormone to estrogen.
The role of testosterone in the male organism
Testosterone is responsible for developing all features characteristic to men, promoting anabolism, stimulating sex drive, highlighting male morphological features. In total, it also improves life quality, its high concentrations are characteristic to people with high energy level and efficient regeneration. In relation to the above, high level of this male sex hormone is incredibly desirable among men. Unfortunately, lifestyle characteristic to the society of the XXI century is not conducive to testosterone secretion. Numerous stress factors, anti-nutritious substances in a diet, lack of sufficient time for regeneration lead to the decrease of testosterone secretion. Therefore, supplements like this one are incredibly desired not only by men who are looking for support in sport achievements, but also those who want to increase their life quality.
Key role of aromatase
Enzyme P450, commonly called aromatase, plays a key role in regulating testosterone level in blood. It stimulates the conversion of testosterone to estrogen. Therefore, its activity has negative influence on the amount of male sex hormone, simultaneously increasing the amount of estrogen. Moreover, testosterone aromatization to estrogen is the main pathway of creating the female sex hormone. Its high concentration, on the basis of loopback, decreases androgen secretion. Due to these two mechanism of aromatase activity towards hormonal balance, keeping its activity under control is incredibly vital to maintain high concentrations of testosterone.
The formula of the preparation was based on the most effective active substances, inhibiting the activity of aromatase P350 and increasing the level of free testosterone in blood. In the composition of the supplement there are:
Epiandrosterone – systematically determined as 5α-androstan-3β-ol-17-one, also called isoandrosterone. It is a steroid hormone, naturally occurring as testosterone metabolite. It demonstrates affinity to androgen receptors, activating them. Its important feature is the fact that it doesn’t undergo the process of aromatization, therefore it cannot be transformed to estrogens. Moreover, it demonstrates the ability to limit the activity of the enzyme P450, stimulating endogenous secretion of testosterone. The ability of epiandrosterone to limit the activity of SHBG is also important, as it binds the male sex hormone to its biologically inactive form.
Chrysin – a bioflavonoid, naturally appearing in propolis (bee glue) and honey. In demonstrates the ability to inhibit DAX-1 protein, which is a negative factor regulation the functions of StAR protein, which determines the level of limiting the synthesis of testosterone in testicles. In this way, chrysin may increase the secretion of the male sex hormone. Moreover, it demonstrates the ability to inhibit the activity of aromatase, transforming testosterone to estrogen.
Indole-3-carbinol – a heterocyclic compound, limiting the ability of estrogens to bind with their receptors. In this way, it promotes the activity of androgens in the organism. Moreover, it is also an inhibitor of estrogen receptors, which also influences health – in this way, it limits the risk of developing cancer. Moreover, it is a precursor of diindolylmethane, which demonstrates the ability to direct precursor forms of estrogens to be metabolized to biologically less active forms.
Eurycoma Longifolia – also known as Ali Tongkat and Long Jack, in traditional eastern medicine used in the therapy of sexual disorders. It is a strong aphrodisiac, considerably increase sex drive. It has two-mechanisms effect. It both limits the activity of estrogens and promotes the synthesis of testosterone, comprehensively influencing the quality of sperm.
Muira Puama – a herb used by Indians as support for men. Its effectiveness is related to the ability to stimulate the activity of androgens in the organism. It positively influences libido, increases sexual ability, supports achieving and maintaining erection. It also has toning effect on the nervous system. It may also increase cognitive skills thanks to the ability to stimulate serotoninergic mechanisms.
Quercetin – a bioflavonoids with a wide spectrum of pro-health effects. It is a strong antioxidant, has anti-inflammatory effect, limits the risk of cancer development. It has protective effect on testicles, limits the effects resulting from their exposition to dioxins, thanks to which it prevents disorders in testosterone synthesis. Although limiting the emission of this compound to the atmosphere is the subject of many pro-ecological activities, dioxins are still a real threat that may take their toll both on health and the functioning of glands secreting testosterone. Quercetin may also limit the activity of aromatase.
Coumestrol – an organic compound belonging to the group of phytoestrogens. It demonstrates the ability to bind with estrogen beta receptors, thanks to which it limits the creation of the female sex hormone. In this way, it promotes testosterone effectiveness in the organism and also limits the development of estrogen-dependent cancers.
Bergamottin - 6,7-Dihydroxybergamottin, is a compound naturally occurring in grapefruits. It is used in dietary supplements in order to increase the assimilability of other components. It protects them from oxidation, increasing their bioactivity.
Naringenin – a bioflavonoid, naturally occurring in grapefruits. It has protective effect on the cardiovascular system, demonstrating the ability to strengthen blood vessel walls and decrease the level of testosterone. As for hormonal balance, it is active as a strong inhibitor of P450 enzyme. In this way, it stimulates the synthesis of testosterone and limits its conversion to estrogens.
Summing up, Hi-Tech Estrogenex 2nd Generation is an advanced preparation allowing to maximize endogenous synthesis of testosterone and its effectiveness in the organism. It significantly influences the activity of estrogens, decreasing it and reducing the activity of aromatase, limiting in this way the creation of the female sex hormone and stimulating the secretion of androgens. Using the preparation makes our work on the body and sports results easier and positively influences life quality and increases sexual abilities.
Microcrystalline Cellulose, Starch, Stearic Acid, Magnesium Stearate, Sodium Glycolate, Triacetin, Silica, FD&C Red #3, FD&C Yellow #6
Proprietary blend - is a complex of bioactive ingredients in the proportions, which are covered by the manufacturer's patent. According to the law in force in Poland, the components of the blend are known, and , by the place on the packaging, you can identify which components are in bigger amount (the components are listed in the decreasing order of amounts).
Proprietary blends are used in many food supplements, such as creatine stacks, no-boosters, fat burners and pro-testosterone supplements, improving libido.
Chrysin (5,7-dihydroxyflavone) is an organic chemical compound from the flavonoid group. In nature, it is found in some plants (including Passiflora caerulea, Passiflora incarnata and Oroxylum indicum), fungi (Pleurotus ostreatus), honey and propolis. In vitro study showed it acts as an aromatase inhibitor, and may also stimulate steroidogenesis. Chrysin is also credited with the ability to increase the sensitivity of Leydig cells to stimulate cAMP, which may result in enhanced testosterone synthesis.
Chrysin also has a broad spectrum of health-promoting properties. It has anticancer potential and may increase the effectiveness of conventional chemotherapy. In addition, it favors reducing the activity of the NF-kβ factor and lowering the level of pro-inflammatory compounds, and thus reduces the intensity of inflammation in the body. It also seems to modulate the level of GABA, and thus it has a relaxing and antidepressant effect.
Supplements usually include chrysin extracted from passiflora flowers. Chrysin has gained the name of an effective natural aromatase inhibitor. Due to its properties, it is often added to formulas aimed at reducing the activity of estrogens and preparations aimed at increasing the level of testosterone.
Dosage: no precise dose has been established. The studies proved the safety of doses of 0.5 g to 3 g per day.
Indol-3-carbinol is an organic compound which is created with myrosinase-treated glucosinolates. A source of its natural form are: vegetables (such as brussels sprout, broccoli, cauliflower). It shows the effect of reducing estrogen levels (particularly important for athletes called strength athletes, helps to improve the aesthetics of the body and body shaping), binds free oxygen radicals and cleanses the body by removing the metabolism debris out the body. It is used as a supplement to help to fight against cancer and by athletes and people with high mental and physical activity. It is available as mono-preparation supplements and complex herbal supplements (including combined with natural extracts of Tribulus and ginseng) in programs for aesthetics of the body.
Dosage: 50-120 mg daily (as customary in sports supplementation).
Quercetin - flavonoid glycoside, which is a natural pigment occurring in plant foods (fruits, vegetables and herbs). A particularly rich source of quercetin are apples, onions and tea. By inhibiting the hyaluronidase enzyme, it protects hyaluronic acid against returning into its monomer. It has a beneficial effect on the cardiovascular system, strengthens the walls of blood vessels. It is an antioxidant. Causes a decrease in histamine showing an antiallergic action. It has anti-inflammatory potential. It is used to treat asthma, diabetes and for weight loss. The supplementation occurs only in combination with hesperidin, rutin and ascorbic acid, in health-related programs, supporting the immunity of the body in the form of creatine stacks and no-boosters. Available at the www.muscle-zone.pl
Dosage: the lack of standards for daily consumption recommended: as customary taken in sport
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