Since 2005
You are currently:
Choose language:
Need help?
Leave message
Choose language:
Select currency: $ £
Since 2005
en
USD
Order:55.00 $111.00 $166.00 $222.00 $
Shipping:-3.00 $-6.00 $-8.00 $-11.00 $
0 0.00 $
Since 2005  sales@mz-store.com  +1 844-530-3647
Folinic Acid 800mcg Folinic Acid 800mcg

Seeking Health Folinic Acid is a dietary supplement providing the organism with folinic acid in the form of calcium salt; a metabolically active form of vitamin B9. This form demonstrates high, more than 90% bioavailability and may be quickly metabolized to other forms, mainly L-methylfolate (the metabolism of which is bilateral; the excess of methylfolate may be retransformed to folinic acid).

Folates, folinic acid, folic acid, methylfolate – what is the difference?
We should clearly highlight the differences between the concepts of folates, folinic acid, folic acid and methylfolate, as similar names may be confusing. Folates stand for the name of the group of compounds demonstrating analogous features to folic acid. Folates include various compounds, i.a. folic acid, folinic acid and methylfolate.

Folic acid is the most basic form of folates, however, it is not directly used by the organism. It needs to undergo proper metabolic processes, which is indicated as its fault, as we need to remember about the loss of the active substance, in each subsequent metabolic process (in other words, it is not very metabolically active). A final product of the cycle of folates is methylfolate, taking part in the processes of methylation in the organism. One of the indirect products is 5,10-CH2-THF; it is the form, the main precursor of which is folinic acid.

Why folinic acid and not folic acid or methylfolate?
In case of the comparison to the first one, the situation is easy. Folinic acid needs a smaller amount of metabolic processes (smaller losses of the active substances) and it demonstrates higher assimilability in comparison to folic acid; additionally, the intake of the excessive amount of folic acid demonstrates unbeneficial health implications.

Differences when it comes to methylfolate are more subtle. Folinic acid will be a better choice for people oversensitive to products influencing methylation processes (mainly people with diagnosed histapenia or genetic disorders of MTHFR gene), as the form of methylfolate may deepen unbeneficial symptoms of diseases. It is also a better choice for people with diagnosed problems with methylcobalamin metabolism or its large deficiencies (the influence of methylfolate and folic acid on the prevention of intensive hair loss was compared in chemotherapy with methotrexate. The application of this drug results in intensive hair loss. Moreover, the influence on limiting this effect by the application of methylfolate and folinic acid was compared. For the second time it demonstrated a much better effect).

Sole folinic acid in the organism may be responsible for:
Neuroprotective and antidepressant effect – decreases the risk of neurologically related poisonings (mainly by heavy metals, dexamethasone and beta-amyloid). It synergistically influences the substances used in antidepressant therapies (drugs from the group of SSRI and TCA); decreases the time needed for their effective activity. Research also proved direct influence of the high level of folates in the plasma on preventing depression and positive influence on maintaining cognitive functions in Parkinson’s and Alzheimer’s diseases.

Antioxidant effect – demonstrates antioxidant activity on DNA oxidative damage (mainly be decreasing the level of homocysteine; 8-0HdG marker responsible for indicating this type of damages was decreased in the study after the intervention with folates).

Protective effect during pregnancy – in proper supplementation during pregnancy, folic acid is able to decrease the risk of neurological complications related to the damages of neural tube in the fetus to 0. Research also indicates the probability to decrease the risk of other defects of the baby, such as cleft lip or palate as well as hypertension of the mother.

Positively influences the circulatory system – it improves blood flow, especially in case of therapeutic application in certain cardiological diseases (e.g. coronary artery disease). Folate deficiency may also cause anemia (folates take part in the production of red cells).

To sum up, Seeking Health Folinic Acid is a good choice for people who want to supplement vitamin B9 more effectively than in case of simple folic acid, and who due to health reasons cannot use L-methylfolate. It will work great as an element of constant and interventional supplementation during pregnancy, depression episodes or problems with the circulatory system.

OutOfStock
Since 2005
Notify me of availability
Folinic Acid 800mcg Folinic Acid 800mcg 60 caps.
Seeking Health
15.96 $

Folinic Acid 800mcg 60 caps.

Servings: 60 caps.
1-2
Location:
EU Stock
Availability:
NONE
Working days
from the dispatch
Minimum expiration date:
2021-04
For free shipping is missing: 68.00 $
15.96 $With VAT

From 3 units only 15.64 $ /Units. -2%

We can let you know you when the product will be available again
Save

Customer Service

(mon.-fri 900-1700

You have got questions about the product

Description
  • The form independent of complications of methylation processes in the organism
  • The form quickly metabolized to other active forms
  • The highest quality folinic acid in an effective dose
  • Supports the processes based on DNA translation
  • Demonstrates antidepressant effect
  • Has neuroprotective properties
  • High bioavailability

Seeking Health Folinic Acid is a dietary supplement providing the organism with folinic acid in the form of calcium salt; a metabolically active form of vitamin B9. This form demonstrates high, more than 90% bioavailability and may be quickly metabolized to other forms, mainly L-methylfolate (the metabolism of which is bilateral; the excess of methylfolate may be retransformed to folinic acid).

Folates, folinic acid, folic acid, methylfolate – what is the difference?
We should clearly highlight the differences between the concepts of folates, folinic acid, folic acid and methylfolate, as similar names may be confusing. Folates stand for the name of the group of compounds demonstrating analogous features to folic acid. Folates include various compounds, i.a. folic acid, folinic acid and methylfolate.

Folic acid is the most basic form of folates, however, it is not directly used by the organism. It needs to undergo proper metabolic processes, which is indicated as its fault, as we need to remember about the loss of the active substance, in each subsequent metabolic process (in other words, it is not very metabolically active). A final product of the cycle of folates is methylfolate, taking part in the processes of methylation in the organism. One of the indirect products is 5,10-CH2-THF; it is the form, the main precursor of which is folinic acid.

Why folinic acid and not folic acid or methylfolate?
In case of the comparison to the first one, the situation is easy. Folinic acid needs a smaller amount of metabolic processes (smaller losses of the active substances) and it demonstrates higher assimilability in comparison to folic acid; additionally, the intake of the excessive amount of folic acid demonstrates unbeneficial health implications.

Differences when it comes to methylfolate are more subtle. Folinic acid will be a better choice for people oversensitive to products influencing methylation processes (mainly people with diagnosed histapenia or genetic disorders of MTHFR gene), as the form of methylfolate may deepen unbeneficial symptoms of diseases. It is also a better choice for people with diagnosed problems with methylcobalamin metabolism or its large deficiencies (the influence of methylfolate and folic acid on the prevention of intensive hair loss was compared in chemotherapy with methotrexate. The application of this drug results in intensive hair loss. Moreover, the influence on limiting this effect by the application of methylfolate and folinic acid was compared. For the second time it demonstrated a much better effect).

Sole folinic acid in the organism may be responsible for:
Neuroprotective and antidepressant effect – decreases the risk of neurologically related poisonings (mainly by heavy metals, dexamethasone and beta-amyloid). It synergistically influences the substances used in antidepressant therapies (drugs from the group of SSRI and TCA); decreases the time needed for their effective activity. Research also proved direct influence of the high level of folates in the plasma on preventing depression and positive influence on maintaining cognitive functions in Parkinson’s and Alzheimer’s diseases.

Antioxidant effect – demonstrates antioxidant activity on DNA oxidative damage (mainly be decreasing the level of homocysteine; 8-0HdG marker responsible for indicating this type of damages was decreased in the study after the intervention with folates).

Protective effect during pregnancy – in proper supplementation during pregnancy, folic acid is able to decrease the risk of neurological complications related to the damages of neural tube in the fetus to 0. Research also indicates the probability to decrease the risk of other defects of the baby, such as cleft lip or palate as well as hypertension of the mother.

Positively influences the circulatory system – it improves blood flow, especially in case of therapeutic application in certain cardiological diseases (e.g. coronary artery disease). Folate deficiency may also cause anemia (folates take part in the production of red cells).

To sum up, Seeking Health Folinic Acid is a good choice for people who want to supplement vitamin B9 more effectively than in case of simple folic acid, and who due to health reasons cannot use L-methylfolate. It will work great as an element of constant and interventional supplementation during pregnancy, depression episodes or problems with the circulatory system.

Directions for use
Manufacturer
Reviews (0)

Composition

Container size: 60 capsulesServing size: 1 capsuleServings per container: 60
per portion (1 capsule)amount%DV
Folate (as folinic acid, calcium salt)800 mcg340%

Other ingrednients

Microcystalline cellulose, HPMC (vegetable capsule), ascorbyl palmitate, and silica.

Similar products
Best to combine with
Jarrow Formulas
37.60 $

Bioavailable iron with lactoferrin (!) Recommended particularly for women.

Buy
Aliness
12.42 $

Bamboo shoot extract, an excellent source of silica. Strengthens the condition of the skin, hair and nails.

Buy
Swanson
5.14 $

Helpful in problems with falling asleep, regulates biological rhythm of sleep and wakefulness.

Buy
Aliness
6.19 $

An effective dose of highly bioavailable copper in the form of a chelate. Free from GMOs, lactose, and gluten.

Buy
Source Naturals
24.08 $

Dietary supplement improving mood. It reduces nervous tension and supports memory.

Buy
Quicksilver
811.26 $

A set containing 4 types of preparations that support body detoxification processes.

Buy

Folinic acid

Information

Folinic acid - 5-formyltetrahydrofolate, a biologically active form of folic acid. Its supplementation is recommended especially to people with methylation dysfunctions, as it is essential for the transformation of folic acid to the active folate. Taking into consideration the increasing tendency to disorders in this respect, folates are more and more often recommended as the basic, preferred forms of supplementation with folic acid.

Supplementation with these folates is especially recommended to women who are planning pregnancy or are pregnant. Folic acid in the biologically active form is responsible for regulating the formation of neural tube in the fetus and is conducive to its proper development.

In adults, folates are conducive to optimal methylation processes. It takes part in transforming homocysteine to methionine, thanks to which it demonstrates positive influence on the health of the cardiovascular system. In this way, it positively influences psyche, as the effectiveness of this process is conducive to the production of S-adenosyl methionine with considerable influence on maintaining proper emotional states.

Some sources also indicate the protective influence of folates on the development of cancers. This information, however, is not fully unambiguous. The present state of knowledge suggests that since the optimal supply of folates really decreases the risk of cancer development, its supplementation in excessively high doses may demonstrate the reverse effect.

 

Calcium

Information

Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess result
ing from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications
are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)

Salt

Information

Salt (sodium chloride, or table salt), natural source of electrolytes (chlorine and potassium), regulating water and electrolyte and acid-base balance of the body, affecting the nervous system and blood pressure. Sodium is an essential element for the proper growth. The proper dose of salt prevents overheating of the body and solar stroke. It provides the proper functioning of muscles and nerves the body. Chlorine in combination with sodium, is involved in the digestive process and maintains acid-base balance in the body, as antitoxin removes toxic products of metabolism in the liver. Salt is a flavour component and preservative of many foods, nutritional supplements and mixtures of electrolytes, available at www.muscle-zone.pl

Dosage: no specific standards of consumption, used so as to provide sufficient amount of electrolytes to the body (sodium and chloride).

 

Latest on blog

When to change your training routines?

When to change your training routines?

Year’s ago, Arnold Schwarzenegger advised his followers to change their weight- training programs every six weeks. The idea was to shock the muscles, which...

Read more
How to build incredible strength?

How to build incredible strength?

Research has shown that the best way to develop strength is to do four to six sets of four to six reps each. Of all the many aspects of strength training, the one...

Read more
The herbs and spices you should have in your cooking toolkit (Part 2)

The herbs and spices you should have in your cooking toolkit (Part 2)

As I was writing my previous blog on herbs and spices I quickly realised that there is so much to say about them that I needed to create a Part 1 and now a Part...

Read more
The Marathon Fuel

The Marathon Fuel

What you eat, and when you eat it, in the days before a marathon may influence your race time. Two studies show: what to eat in the days before the race. Loading...

Read more
Squat Jump

Squat Jump

The squat jump is the ultimate combination exercise and it’s a real ass-kicker to boot, taking the mechanics of a squat and adding the power component of a...

Read more
Past Failure – who can train like that?

Past Failure – who can train like that?

It seems every day someone comes along with a new and improved system of weight training scientifically designed to stimulate the muscle fibres unlike any other...

Read more

Sign up for our newsletter
And receive coupons, news, special offers and much more!

Customer service

MZCatalog - recommended dietitians

MZCatalog - recommended trainers

MZCatalog - recommended clubs

Supps4You LLC
16192 Coastal Hwy Lewes, Delaware 19958
sales@mz-store.com +44 7767803657