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Source Naturals, BioPerine is a dietary supplement containing the extract from black pepper. This commonly known spice hides in itself piperine – a substance commonly used to treat digestive disorders, which also demonstrates analgesic, anti-inflammatory and antifebrile effects. However, most often piperine is used as bioavailability booster of vitamins, minerals and various nutritious substances.
Piperine is an alkaloid with wide spectrum of pro-health properties. It naturally appears in fruits and the root black pepper (Piper nigrum) or long pepper (Piper longum). In supplementation, we most often come across the term bioperine, which means a patented, standardized black pepper extract, containing at least 95% of the active substance.
The influence of piperine on nutritional substances assimilability
The absorption of vitamins, minerals and other nutritional substances is one of the most important issues both for supplementation and for general dietetics. Providing the organism with the components essential for health is very important, but the most crucial is making them properly absorbed and utilized.
Bioperine affects these mechanisms that are used by the organism to control the availability of nutritional elements for cells. In other words, it improves assimilability of vitamins, minerals and nutrients and by the same token it intensifies the activity of supplements, to which it has been added.
The improvement of bioavailability is possible thanks to inhibiting the activity of many enzymes (i.a. glycoprotein P and CYP3A4, cytochrome 450), important for the synthesis and transport of low molecular compounds. In the course of clinical research it has been proven that bioperine improves the absorption and utilization of curcumin by more than 2000% and moreover, it decidedly increases the absorption of selenium, vitamin B6, vitamin C and other nutritious substances contained in food.
Piperine as a natural thermogenic
Bioperine facilitates the process of thermogenesis. By activating thermogenesis, it intensifies lipolysis, i.e. spare fat breakdown, which constitutes a basic fuel for thermogenesis. At the same time it inhibits protein catabolism.
By inhibiting the activity of nicotinic acid and acetylcholine, bioperine contributes to the increase of cAMP level. High level of cAMP is equivalent to increased thermogenesis, lipolysis and anabolism as well as reduced catabolism. Additionally, thanks to the direct stimulation of thermic receptors, it starts thermoregulatory processes and more intensive emission of thermal energy outside the organism and as a consequence a more intensive burning and higher utilization of spare fat.
Improvement of digestive system work
Black pepper for centuries has been used not only as taste intensifier, but also as a seasoning improving digestion and reducing gastric ailments.
Bioperine stimulates nerve fiber ends of the digestive tract, thanks to which it increases the production of gastric juice. Moreover, it stimulates the secretion of digestive enzymes and bile acid. The digestive system prepared in such a way deals easier with the breakdown and absorption of the substances contained in food.
Unique properties of piperine
Bioperine has anti-depressant effect and may be used as antidote for chronic stress. It influences catecholamine synthesis and research carried out on rodents also proved its high activity in the hippocampus.
Piperine is a natural, herb inhibitor of vanilloid receptor TRPV1. It is a certain protein that is responsible for the feeling of pain. Piperine blocks the activity of TRPV1, thanks to which it effectively alleviates pain symptoms.
By inhibiting the activity of 5-alpha-reductase enzyme, bioperine stops androgenic pattern baldness and in the studies in vitro and in vivo it has been proven that it may even stimulate the growth of new hair.
Summing up, BioPerine is a universal pro-health supplement. It is recommended especially as an additive to other supplements – by the improvement of the bioavailability of the substances contained in them, it allows to fully use their treatment potential. Thermogenic properties of bioperine make it an ideal preparation supporting weight loss.
For best results, take 1 tablet with a vitamin supplement 30 to 60 minutes before meals. Do not exceed 2 tablets daily.
Source Naturals is an American vitamin and herbal supplement provider, created in year 1982. The company specialize in producing nutritional formulations for the maintenance of well-being and the enhancement of life – they introduced numerous award-winning formulas, recognized for their excellence in independent surveys and nutritional analyses.
The company also provides education that empowers individuals to take responsibility for their health.
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