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Thorne Thyrocsin is a complex formula that aims at supporting the functioning of the thyroid. It contains a combination of carefully selected vitamins, minerals, and nutrients, enriched with an ashwagandha extract. The synergic activity of all of its components makes it possible restore normal thyroid functions and prevents disorders in its activity.
The preparation is a perfect element of thyroid disease prevention. It is particularly recommended for people who suffer from the symptoms typical of hypothyroidism, such as tiredness for no apparent reason, a low mood, a constant sensation of cold, gaining weight despite a normal caloric balance. An indication for supplementation can also be worse hormone test results. Even if they are still within normal laboratory values, the results being near the extremes of norms can suggest that the activity of the thyroid is weakening and that it needs some thorough support.
Significance of the thyroid for the organism
The thyroid is a small endocrine gland consisting of two lobes, which are located in the lower part of the neck and whose shape resembles butterflies. The main role of the thyroid is the production of two hormones – thyroxine (T4) and triiodothyronine (T3). They are essential for the normal functioning of nearly every cell in the organism, regulate metabolism, and are responsible for maintaining the right dynamics in the human life.
There are many factors that can distort thyroid functions, for example chronic stress, improper diet, deficiencies of some vitamins and minerals, the use of pharmacological agents (like oral hormonal contraceptives. Usually, it turns out that a weakened thyroid produces too little of the hormones T3 and T4, and the conversion of T4 to T3 is insufficient when compared with the needs of the entire organism. What also occurs sometimes is the hypertrophy of reversed triiodothyronine (rT3), which inhibits necessary hormonal transformations by blocking thyroid hormone receptors.
There is an entire range of natural compounds that can improve the functioning of the thyroid and stimulate its normal activity in case it deteriorates. Sometimes, it is enough to provide the organism with the right supply of specific vitamins, minerals, and nutrients for the thyroid to function with no problems. The manufacturer of the preparation contained all of the crucial compounds in it. Both their dosage and forms were selected carefully so that the bioretention is optimal and the organism is provided with everything it needs.
The T3- and T4-increasing complex contains crucial nutrients and plant substances whose complex mechanisms of activity give the preparation the ability to increase thyroid hormone levels. The process of the greatest importance is especially the increased production of thyroxine, which serves as a substrate in the conversion into triiodothyronine.
Iodine is one of the so-called trace elements. It not only supports thyroid functions, but it is absolutely essential for its normal functioning. The thyroid uses iodine for the synthesis of hormones – triiodothyronine produced by it has three iodine atoms, while thyroxine contains four.
L-tyrosine is one of the main endogenous amino acids. When it comes to the functioning of the thyroid, the most important thing is that tyrosine cooperates with iodine and is a precursor of T3 and T4. Both triiodothyronine and thyroxine are iodinated tyrosine derivatives. Too low a tyrosine supply distorts the production of thyroid hormones, and its consequence is usually hypothyroidism.
Ashwagandha comes from India, where it has a long history of medical applications. Traditionally, it is used as an adaptogenic herb that helps to restore the homeostasis and facilitate the adaptation of the organism to harmful conditions (for example, chronic stress). The properties are also extremely valuable for the normal functioning of the thyroid gland. Long-lasting stress stimulates the overproduction of cortisol, which in turn increases the level of rT3 and distorts the functioning of T3.
As an adaptogen, ashwagandha supports the organism’s normal response to stress. Tests have proven that apart from reducing cortisol levels, ashwagandha extracts also increase the concentration of T3 and T4 in the serum. Experiments conducted on rodents proved that after only 20 days of supplementation, T3 levels increased by 18%, and T4 levels – by as much as 111%. On the other hand, tests on people showed that patients who used ashwagandha not only had higher T4 levels, but also the TSH results were additionally enhanced.
The complex stimulating T4 conversion to T3 contains a mix of minerals essential for the normal process of T4 conversion to T3. It is an important process because even though T3 is the crucial enzyme with a much stronger effect than T4, the thyroid releases about 20 times more T4 than it does T3. As the conversion of T4 to T3 decreases, the levels of T3 and fT3 (free triiodothyronine) drop and the secretion of inactive rT3 increases. All that leads to serious disorders in the functioning of thyroid dependent systems and organs.
Selenium participates in the synthesis of thyroid hormones, inhibits the production of thyroid antibodies, and improves the conversion of T4 to T3. It is an essential component of a group of enzymes responsible for removing the iodine atom from thyroxine while it is being converted to triiodothyronine. Numerous tests have demonstrated that patients suffering from various thyroid disorders always have too low selenium levels in the organisms.
Selenium also plays a major role in protecting the thyroid gland. It protects its cells from oxidative damage, which can occur in the reactions that lead to hormone synthesis accompanied by the release of hydrogen peroxide. Properly high selenium levels are also crucial for protecting thyroid cells from the damage caused by excessive iodine concentration.
Zinc is one of the most important trace elements in the organism. The thyroid can convert T4 to T3 only in its presence. What is more, zinc is also needed for the hypothalamus. Thanks to the element, the hypothalamus releases TSH (thyroid-stimulating hormone), which in turn sends a signal to the pituitary to stimulate the activity of the thyroid.
Copper occurs in the organism in very small amounts; however, scientists have proven that its deficiencies are potentially lethal. Copper and zinc are a unique duet. Large amounts of zinc inhibit the absorption of copper and can lead to a dangerous deficiency, so it is advised that zinc supplementation be accompanied by copper as well.
Copper deficiency inhibits the conversion of T4 to T3, and it additionally distorts the functioning of the hypothalamus. Without the right amount of copper, it is unable to regulate the functioning of the thyroid properly.
The complementary ingredient complex includes vitamins that are unjustifiably omitted in blends directed at improving the functioning of the thyroid. Meanwhile, by enhancing biochemical processes that take place in the system, they also bring factual benefits for normal thyroid functions.
Vitamin B12 mainly regulates the functioning of the nervous, circulatory, and digestive systems; however, many tests have demonstrated that its deficiencies are correlated with the distorted functioning of the thyroid, especially hypothyroidism. Some scientists suggest that too low a vitamin B12 supply increases the production of rT3, that is the biologically inactive form of the hormone T3.
Vitamin C is rarely associated with the thyroid; meanwhile, its right supply is essential for its normal functioning. Thyroid disorders are often a consequence of adrenal exhaustion and the overproduction of cortisol as a result of chronic stress. Chronic stress distorts the hypothalamic-pituitary-adrenal axis (HPA). The thyroid is activated by the functioning of the hypothalamus and the pituitary, so everything that distorts the HPA axis has also a negative effect on thyroid functions. It works the other way round, too – everything that helps to reduce cortisol levels and restore the homeostasis of the HPA axis enhances the functioning of the thyroid.
Vitamin C is one of the most efficient agents when it comes to enhancing the functioning of the adrenals and regulating cortisol levels. Many tests have demonstrated that increasing vitamin C supply helps to restore normal TSH values.
Vitamin E is an extremely powerful antioxidant. In that respect, it is also supported by vitamin C, another efficient antioxidant. Protecting cells from the harmful activity of free radicals is also crucial for the thyroid. Antioxidants protect the liver from damage, the organ that is exposed to oxidative stress the most. The liver is the place where T4 is converted to T3 and the centre of secreting carrier proteins for thyroid hormones. Many tests have demonstrated that hepatic insufficiency has a negative effect on the functioning of the thyroid.
To sum up, Thyrocsin is a tested combination of the most efficient compounds designed to support the functioning of the thyroid in many ways. The thyroid gland is an organ that regulates the entire life activity of a human being, so caring for its basic functions is essential for normal mental and physical well-being.
The supplement contains a combination of efficient thyroid-optimising substances. In order to achieve the desired effects, take two capsules twice a day. It is good to take them with a meal containing a source of fat, as some of the compounds present in the preparation are fat-soluble.
The preparation contains a rather large dose of iodine. People allergic to iodine should maintain caution and consult a specialist before they start supplementation.
Thorne Research is a company that since 1984 has been engaged in the production of the highest quality dietary supplements based on innovative recipes. Thorne Research in cooperation with other leaders on the market also produces pharmaceutical, therapeutic and medical preparations.
Thorne Research offers a wide range of products that are trusted worldwide by professionals in the healthcare sector. The activity of the products has been confirmed by numerous clinical tests. The company also has GMP, TGA and NSF certificates, which demonstrates compliance with relevant standards related to the production and safety of use.
The manufacturer constantly raises the bar and focuses on continuous development and improvement of the products by implementing the latest technological solutions and employing top-class specialists.
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|per 2 capsules||amount||%DV|
|Vitamin C (as Ascorbic Acid)||200 mg||250%|
|Vitamin E (as d-Alpha Tocopheryl)||67 mg||558%|
|Vitamin B12 (as Methylcobalamin)||100 mcg||4000%|
|Iodine (as Potassium Iodide)||225 mcg||150%|
|Zinc (as Zinc Picolinate)||5 mg||50%|
|Selenium (as Selenium Picolinate)||100 mcg||182%|
|Copper (as Copper Picolinate)||500 mcg||50%|
|Ashwagandha extract (root) (Withania somnifera)||90 mg||*|
Hypromelose (derived from cellulose) capsule, Leucine, Silicon Dioxide.
Vitamin C (ascorbic acid) it is a vitamin soluble in body fluids, can be taken from foods (fruits and vegetables), or as drug derived synthetically. The largest of its resources can be found in broccoli, Brussels sprout, kale, black currant fruit and hawthorn, citrus fruits, tomatoes, Savoy cabbage, potatoes. In fact, intake of vitamin C of the food products does not limit the absorbed quantity. Vitamin C (ascorbic acid) is a potent antioxidant, it is an antitoxic, increasing the immune system due to the elimination of risk of bacterial contamination. Vitamin C prevents rupture of blood vessels, affects the blood cholesterol level. It substantially increases the absorption of iron. Inhibits the growth of cancer cells. Lowers stress levels.
Vitamin C deficiency causes abnormal development of connective tissue, cracking capillaries, abnormal calcification of bone tissue, impaired absorption of iron, scorbutus. With the lack of vitamin C, all kinds of injuries do not heal up properly. Vitamin C deficiency can be caused by smoking; each cigarette is destroying up to 100 mg of vitamin C.
Dosage: The demand is 60-80 mg daily. It does not limit the ability to consume higher doses. Some side effects may occur only with longer taking of synthetic vitamin C.
Ascorbic acid – vitamin C. Its biologically active form is the L-isomer, which negatively rotates the polarised light, so that it is a dextroisomer (laevorotatory vitamin C does not exist). It is a strong antioxidant; it reduces the amounts of free radicals, which reduces oxidative stress, a factor leading to cell apoptosis, which is why it is indicated to be a cause for premature ageing.
It supports the immune system functions and increases body system immunity. It is an essential element of the collagen synthesis path, which is why it positively affects the condition of connective tissue. Hence, it promotes also wound healing and increases the durability of capillary vessel. It is involved in transformations of tyrosine and carnitine as well as of some nutrients, so that it affects metabolism. It can also have an impact on the nervous system functions, as it reduces mental fatigue.
Higher supply of vitamin C is especially recommended in the periods of more intensive body system burden, after infections and in order to accelerate regeneration. The indications for increased supply of the vitamin are also hard physical work or intensive trainings.
Vitamin E (tocopherol) is a fat soluble. Due to its antioxidant action, it is a protection of other vitamins (e.g. Vitamins A). Protects the body against free radicals, strengthens the walls of blood vessels and its capacity, causing their dilation and dissolution of blood clots. With the reduction of coagulation, it is used as an antiatherogenic medicine, it allows for the proper course of pregnancy. In cooperation with selenium it slows the ageing process of cells, strengthening connective tissue. In the food it is present in whole-grain bread, sprout and grains, vegetable oils (soybean, sunflower), soya beans and sunflower seeds, vegetable fat and hen egg yolks. Also it is used in sports medicine in the form of nutrients and supplements.
Vitamin E deficiency reduces building of red blood cells, results in changes in muscle and disorders of pregnancies.
Dosage: for children, 0.5 mg / 1 kg of weight; for adults 10-30 mg per day.
What is methylcobalamin?
Methylcobalamin is a biologically active form of vitamin B12. It is one of the two forms of this vitamin that may be used as cofactors in various reactions. It differs from popular cyanocobalamin in the presence of methyl group instead of cyanide, thanks to which it releases the organism from the need of neutralizing this harmful factor.
The methyl group from methylcobalamin may be transferred to homocysteine, thanks to which it comes back in the form of methionine in order to be further converted to SAMe, which is the main donor of methyl groups in our organism. These methyl groups may be then used in the processes of creatine production, in neurotransmitter metabolism and as DNA methylation, thanks to which we achieve proper energy level, better well-being and generally better condition of the organism. B12 is a coenzyme for three enzymes: isomerase, methyltransferase and dehalogenase.
Apart from the influence on the nervous system, the supply of vitamin B12 is also very important for the proper synthesis of red cells as well as hemoglobin and anemia prevention.
Methylcobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
Iodine - more than two-thirds of iodine is stored in the thyroid gland and it is a component produced by it hormones - thyroxine and triiodothyronine, which are essential in the metabolism of proteins, carbohydrates and minerals and regulating the processes of growth, causing it usefulness in sports supplementation. It is also the ingredient of weight loss products. Regulates and controls body temperature. Natural source of acquisition of iodine are: bladderwrack, seafood, sea fish and onion and vegetables growing in soil containing this element and most of all iodized salt ..
Deficiency of iodine in the body cause hypothyroidism, and consequently overweight, mental slowing (cretinism inclusive). It is the cause of a goitre. Iodine deficiency can be caused by rhodanates and polyphenols (e.g. contained in cabbage and cauliflower), hemagglutinin found in legumes.
Excess iodine can result in inhibition of thyroid hormone synthesis (this happens in a small percentage of cases).
Dosage: Treatment of iodine should be done under medical supervision. Daily demand for adults is 150 mcg. For pregnant women daily demand increases to 175 mcg.
Potassium and sodium regulate the body's water resources, ensuring normal heart rhythm. Maintaining the proper level of potassium provides the proper oxidation of the brain, lowers blood pressure, increases the permeability of cell membranes (as an antagonist of calcium). It is a base-forming element. It is widely used in sports diet before and after training in the form of supplements, nutrients, vitamin-mineral preparations and minerals, concentrates and ready, isotonic and hypertonic beverages. Natural sources of acquisition of potassium are: vegetable products (bananas, citrus fruits, melons, mint leaves, green vegetables, potatoes) and animal products (sea fish, meat). Potassium is present in the form of organic compounds: citric acids, and fumarates gluconates and inorganic (chlorides, sulfates, oxides and carbonates).
Potassium deficiency (hypokalemia): excessive tiredness, headaches and irritability, problems with sleeping, muscle cramps, constipation. Potassium levels may drop sharply in the event of a reduction in blood sugar levels, prolonged starvation, severe diarrhea. They can occur when too much of strong coffee is consumed, with alcohol abuse and when eating too much sweets.
The excess of potassium (hyperkalemia) is often the cause of depression, hypotension, tingling in the extremities.
Zinc (chemical element from transition group 12) belongs to the trace elements, it helps maintain acid-base balance of the body, protein, energy, lipid and carbohydrate metabolism. It provides bone metabolism and transport of oxygen. It protects the body against free radicals. Necessary for the proper operation of the senses of taste and smell. Positive impact on the process of insulin metabolism in the pancreas. It supports visual adaptation to the dark, has a significant influence on brain function. It is helpful in the treatment of infertility and mental illness.
Zinc deficiency leads to decreased immunity, and growth retardation. Zinc deficiency can occur in case of excessive consumption of simple sugars. In the case of hormonal therapy of women with irregular menstruation, the therapy should be associated with increased consumption of zinc. It can be found in food like: beans, eggs, carrots, beef and pork meat, milk, nuts, citrus fruits, seafood, rice, cottage cheese, lettuce.
Dosage: Daily 12-15 mg zinc. Exceeding the daily dose of 20 mg cause symptoms of poisoning of the body.
Zinc picolinate – an organic zinc salt, its highly available form of proven ability to increase the element level in the body system. Zinc belongs to the microelements essential for the human body system and the demand results mainly from the fact that it is present in active centres of many enzymes conducting the reactions responsible for homeostasis.
It forms also protein domains binding DNA, called also zinc fingers, which determines the activity of many regulatory proteins. The proper supply of zinc ensures smooth functioning of the immune system. It affects also metabolism, both by modifications of digestive enzymes activity and influence on insulin secretion in beta pancreatic cells.
Zinc protects also the cells from the action of free radicals. The proper supply of the element can also increase testosterone synthesis, as it reduces the activity of aromatase. In men, zinc prevents prostate cancer and in women – regulates menstruation.
Selenium (element, chemical symbol Se, atomic no. 34, from chalcogenide, it is present in several allotropic forms). It is supplied the body with food in the form of seleno-amino acids (selenomethionine - gathering supplies, and selenocysteine – a component of glutathione peroxidase, deiodinase and seleno-proteins). Regulates the functioning of the thyroid gland. It affects the growth and development, including sexual development (by increasing production and sperm motility). It affects the flexibility of the tissue, removes some of the toxins from the body and destroys cancer cells and reduces the severity of menopause in women. Natural products containing selenium are seafood (sea fish, oysters, bladderwrack) and vegetable products (broccoli, onions, wheat germ, bran, tomatoes) and animal products (poultry, eggs). It is also included in the composition of vitamin-mineral and mineral supplements. Selenium supplementation is recommended as a dietary supplement of active people having diet poor in this element, and as a factor increasing the body's immunity.
Selenium deficiency increases the risk of developing cancer and heart disease. Symptoms of selenium deficiency are: cardiomyopathy, growth stoppage, disorders of detoxification processes which may lead to damage to the kidneys and liver.
An excess of selenium can lead to selenosis (the disease, the symptoms are: loss of hair, nail cracks, lesions).
daily demand of selenium for pregnant women 65 mcg; nursing mothers 75 mcg; men 7 mcg.
Copper - trace mineral that facilitates the introduction of iron into hemoglobin, allowing the correct functioning of antioxidant processes. It is an important component of enzymes that affect the processes of aerobic metabolism, carbohydrate metabolism and in the formation of collagen. With proper diet, do not use supplements containing copper, as an overdose can cause insomnia, hair loss. It occurs in foods such as legumes, offal, plums, seafood. Copper compounds must be used in a responsible way, because many of them have toxic properties.
Dosing: A sufficient amount of copper provides proper diet.
Tyrosine - endogenous amino acid (synthesized within the body), one of the 22 protein amino acids building. It occurs naturally in animal food products (eggs, dairy, meat). If the deficiency, it can be synthesized by hydroxylation of phenylalanine, capable of being converted to tyrosine in the liver. It is a precursor of neurotransmitters: dopamine (the group of catecholamines, participating in the processes occurring in the nervous system, causing muscle coordination and participates in the synthesis of many hormones) and noradrenaline (counteracting stress, stimulating the heart and circulatory system, and increasing glycogenolysis and lipolysis participating in the processes of energy transformations). Tyrosine is a precursor of thyroid hormones responsible for the rate of change in metabolic processes and pigment (melanin). In the supplementation, preparations containing tyrosine are used in programs reducing body fat (weight loss), improve mood and are stimulants.
Dosage: Customarily 500-2000 mg per day.
Ashwagandha (Wythania somnifera / Indian ginseng) - a plant of the nightshade family, used in Oriental medicine as a means of adding vitality, improves the psychophysical condition. It is used as an aphrodisiac. The root of the plant is a rich source of bioactive compounds (phytosterols, glycosides, withanolides etc.). The sports supplementation, herbal preparations, a positive effect on the nervous system (reduces stress, and accelerates the adaptation to changing conditions psychophysical), hematopoietic and immune systems. It has a decisive influence on the process of synthesis of nitrogen oxides and the level of certain hormones, including testosterone (e.g. improving sexual functions).
Ashwagandha (Withania somnifera) is a component of the complex herbal supplements (as well as sets of adaptogens) increase the level of the male sex hormone (testosterone), supporting the sexual function of the body, supporting regeneration and having a calming effect.
Dosage: 300-600 mg of extract per day.
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