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Source Naturals NADH is a dietary supplement with NADH (Enada® Co-E1® NADH), i.e. a bioactive form of vitamin B3. The formulation is targeted at increasing energy production in the body, thereby positively influencing mental and physical performance. It is available in the form of gastro-resistant tablets for maximum absorption.
NADH is a reduced form of nicotinamide adenine dinucletodide (NAD), which occurs also in the oxidised form (NAD+). Both compounds are synthesised from vitamin B3 (niacin). NADH and NAD+ are coenzymes in biological redox reactions and thus create a redox system. They are present in all cells of the living organism and are necessary for their normal metabolism, including cellular energy production.
NADH pathways in the body
NADH is formed by the oxidation of compounds which function as “metabolic fuel” and are produced in biochemical pathways, such as glycolysis and the citric acid cycle. NADH oxidation in the mitochondrial respiratory chain leads in turn to the regeneration of NAD+, thereby resulting in the production of ATP – the basic energy compound.
NADH for longevity and anti-ageing effects
NAD+ activates sirtuins – a group of proteins referred to as longevity enzymes. They help regulate the body’s ageing processes and influence lifespan. There is an increasing body of scientific evidence suggesting that enhanced sirtuin activity is associated with anti-ageing effects, long-term health and continuing vitality. By providing NADH, which may be reduced in the body into NAD+, niacin may help stimulate sirtuin acticity.
NADH for higher energy levels
The NAD+/NADH system regulates energy production in the mitochondria. Since NADH is involved in cellular energy production as ATP, optimal levels of this substance and normal NADH-NAD+ ratio cause an increase in mental and physical energy levels. Insufficient ATP production is one of the hypotheses explaining the cause of chronic fatigue.
Aid to metabolic problems
The intake of NAD+ precursors has been shown to help combat metabolic syndrome. Optimal NAD+ levels prevent the development of obesity by promoting the utilisation of fats as energy substrates, increasing energy expenditure and improving insulin sensitivity.
Symptoms of NAD+ deficiency
The main factors which contribute to NAD+ depletion in the body include ageing, high-calorie diet and regular alcohol consumption. A deficiency of this compound may be manifested in chronic fatigue, weight gain, impaired glucose tolerance and insulin sensitivity and faster ageing.
To sum up, Source Naturals NADH is a high-quality supplement which promotes energy production in the body. It is recommended especially for chronic fatigue and lack of motivation and to boost vitality and energy levels and slow down ageing processes. It is also indicated for persons with a busy and stressful lifestyle.
NADH supplementation increases energy levels, but does not cause addiction like e.g. caffeine.
In order to stimulate further sirtuin activity, it is recommended to take supplements which contain resveratrol.
Source Naturals is an American vitamin and herbal supplement provider, created in year 1982. The company specialize in producing nutritional formulations for the maintenance of well-being and the enhancement of life – they introduced numerous award-winning formulas, recognized for their excellence in independent surveys and nutritional analyses.
The company also provides education that empowers individuals to take responsibility for their health.
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Mannitol, sodium bicarbonate, microcrystalline cellulose, chlorophyllin, magnesium stearate, sodium ascorbate, and sodium alginate.
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