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Bio-Kult Migrea is a unique dietary supplement, supporting the proper functioning of the nervous system, digestive tract, and improving immunity. The composition of the preparation, consisting of vitamin B6, magnesium, and live bacterial cultures, has been designed to effectively affect both the nervous and digestive systems.
Nervous system support, fatigue reduction, and mood improvement
Probiotic bacteria found in the presented supplement are carefully selected microorganisms that have a proven positive effect on the nervous system. By settling in the intestines, they contribute to the regulation of the concentration of pro-inflammatory and anti-inflammatory cytokines in the brain and also affect the production of neurotransmitters such as acetylcholine, GABA, and serotonin. Thanks to these mechanisms, probiotic bacteria can be of great importance for the proper functioning of the nervous system, reduction of headaches, and even reduction of the body's adverse reaction to stress.
What's more, this preparation allows the simultaneous supply of magnesium and vitamin B6 to the body, which reduces fatigue and drowsiness, favorably affects the well-being and, as a consequence, exerts a positive effect on cognitive functions. Therefore, they provide support for learners and people doing intellectual work.
The proper functioning of the digestive tract and an improved immunity
This supplement is also key to the improvement of the functioning of the digestive and immune systems. Intestinal bacteria have a positive effect on the regulation of intestinal peristalsis and food absorption; they are involved in the synthesis of certain vitamins and increase immunity. Consequently, they may contribute to the reduction of gastric ailments, prevention against diarrhea and vitamin deficiencies, as well as increase protection against infections.
To sum up, Bio-Kult Migrea is a specialized preparation, whose action is directed at the gastrointestinal tract and nervous system. The carefully selected and proven formula of this product makes it an excellent choice for people who want effective and noticeable support for the intestines and brain.
For better results arising from the supplementation of this product, ensure proper nutrition, sleep hygiene, and physical activity, as well as avoid alcohol and stress. It is also important to include preparations with nootropic and adaptogenic effects in supplementation.
People who do not like swallowing whole capsules, can separate them and pour the contents into a drink or add to food.
Bio-Kult is a company specialising in the production of multistrain probiotic formulas which help achieve balance of intestinal microflora and supports the immune and digestive system. All bacterial strains by Bio-Kult are fully identified and stored at the National Collection for Industrial, Marine and Food Bacteria (NCIMB). Because of that, it is possible to reproduce them safely without genetic shift. To ensure the best quality, both raw material and final products are subject to constant analysis, not only during the production cycle but also during storage.
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|per portion (2 capsules)||amount||%DV|
|Magnesium (as magnesium citrate)||130 mg||**|
|Vitamin B6 (as pyridoxine hydrochloride)||60 mg||**|
|2 billion live bacteria||2*10^9 CFU||**|
|Lactobacillus casei PXN® 37™|
|Lactobacillus plantarum PXN® 47™|
|Lactobacillus rhamnosus PXN® 54™|
|Bacillus subtilis PXN® 21®|
|Bifidobacterium bifidum PXN® 23™|
|Bifidobacterium breve PXN® 25™|
|Bifidobacterium longum PXN® 30™|
|Lactobacillus acidophilus PXN® 35™|
|Lactococcus lactis ssp. lactis PXN® 63™|
|Streptococcus thermophilus PXN® 66™|
|Bifidobacterium infantis PXN® 27™|
|Lactobacillus delbrueckii ssp. Bulgaricus PXN® 39™|
|Lactobacillus helveticus PXN® 45™|
|Lactobacillus salivarius PXN® 57™|
Vegetable capsule (hydroxypropyl methylcellulose).
Magnesium (element from the group of alkaline earth metals, atomic no. 12, a chemical symbol - Mg), one of the most important health microelements, participates in the synthesis process of the disintegration of high energy compounds and processes of transformation of hydrocarbons and fats. It affects the dilation of blood vessels and lower blood pressure, prevents hypercoagulable state. Shortages affect cardiac arrhythmias, malignant muscle cramps, insomnia and anxiety. It is a component of many dietary supplements and found in foods such as whole grain bread, legumes, buckwheat, rice, fish, meat, as well as chocolate, cocoa and nuts.
Dosage of 100 - 500 mg / day
Magnesium citrate is a salt of magnesium and citric acid. It constitutes one of the best assimilable forms of magnesium, which plays many important functions in the organism. It is responsible, among others, for the proper work of the nervous, immune and muscle systems.
Magnesium has calming effect by decreasing the excitability of nerve cells. Thanks to introducing this element to a diet, we may potentially improve sleep quality and reduce the level of stress.
Positive influence on the circulatory system is another feature of magnesium. It prevents hypertension and storage of cholesterol in the walls of blood vessels (arteries), thanks to which it may prevent diseases related to the circulatory system.
Magnesium also plays a considerable role in the process of muscle contraction, therefore it influences the activity of the whole muscle system. It also takes part in the proper synthesis of protein, the process of cell division and proper course of energy metabolism. It helps to maintain healthy teeth and bones and general electrolyte balance in the organism.
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
What is pyridoxine hydrochloride?
Pyridoxine hydrochloride is a basic, the most commonly used form of vitamin B6 in supplements and fortified foods. It is a vitamin soluble in water. It converts to the active form of the vitamin - pyridoxal phosphate.
Vitamin B6 is a cofactor in many enzymatic reactions. It takes part in the production of many neurotransmitters, such as GABA, serotonin and catecholamines and it takes part in the metabolism of amino acids, carbohydrates and lipids. It is an important factor for the process of the creation of red cells and hemoglobin and its deficit may be one of the factors causing anemia. This vitamin contributes to maintaining proper energy metabolism and is important for maintaining well-being and good psychological condition. Its presence supports the breakdown of pro-inflammatory homocysteine to cysteine and further metabolites, thanks to which it may decrease the risk of atherosclerosis and cardiological incidents.
Pyridoxine hydrochloride may be found in many vitamin B complexes and vitamin-mineral preparations available in the offer of muscle-zone.pl.
What is Lactobacillus casei?
Lactobacillus casei is a bacterium of the genus Lactobacillus which ferments lactic acid. The substrates for lactic acid production are sugar compounds, such as glucose or lactose. Due to its ability to break down the disaccharide lactose to simpler carbohydrates, the bacterium can reduce dairy intolerance. It is found in the urinary bladder where it thus competes with pathogens of the urinary system and reduces infections and the incidence of cancer.
Lactobacillus casei supports the treatment of ailments associated with stomach ulcers caused by Helicobacter pylori and treats diarrhoea related to Clostridium difficile infection. Promising results of studies were obtained in relation to the influence of this probiotic strain on the occurrence of allergies. Therefore, its positive effect has been demonstrated on acne, dermatitis, respiratory tract infections, problems with oral cavity and rheumatoid arthritis. By controlling digestion, it helps to maintain a healthy cholesterol ratio.
Lactobacillus casei is found mainly in complex probiotic or symbiotic formulas available at www.muscle-zone.pl
What is Lactobacillus plantarum?
Lactobacillus plantarum is a strain of gram-positive, motionless, rod-shaped bacteria which ferment milk in the intestinal environment. These probotic strains are believed to be the most resistant to adverse conditions prevailing in different sections of the digestive tract. Apart from the small intestine, they were detected in the oral cavity and even vagina where they compete with pathogenic microorganisms, protecting the body from bacterial infections, viruses and mycoses.
They affect the vitality of pathogens and synthesis of compounds beneficial to the health of, e.g. lactic acid and short-chain fatty acids. As a result, it normalises intestinal function, thereby ensuring proper digestion and nutrient absorption. By using the lactase enzyme, it has the ability to break down milk sugar which is the cause of many unpleasant digestive ailments in the majority of adults.
It is used in medicine for treating irritable bowel syndrome, problems with digestion and Crohn’s disease. It is used in supplementation as one of the components of complex probiotics available at www.muscle-zone.pl
What is Lactobacillus rhamnosus?
Lactobacillus rhamnosus is a kind of milk fermentation bacteria capable of synthesising the enzyme which breaks down lactose. Owing to that, it reduces the discomfort after consuming dairy products. Furthermore, it populates the intestinal mucosa and competes with pathogenic bacteria, thereby helping restore the normal intestinal microflora. The proper condition of intestines ensures efficient food digestion and proper immunity against pathogenic microorganisms but also contributes to reducing inflammations and allergies in the body.
This bacteria strain is found mainly in complex probiotic or symbiotic formulas available at www.muscle-zone.pl
Bifidobacterium bifidum – what is it?
Bifidobacterium bifidum is a Gram-positive bacteria strain of the Bifidobacterium genus. It is non-motile, anaerobic and rod-shaped. In the human body system, it is present mainly in the large intestine, but also in the final parts of the small intestine, vagina and mother’s milk. It is one of the most commonly used strains in probiotic preparations.
The benefits of the use of probiotics containing this bacterium include smaller risk of diarrhoea, induced both by infections and antibiotics, as well as lower risk of infections caused by Escherichia Coli bacteria. It can be also helpful in restoring bacterial homeostasis in vagina. Bifidobacterium bifidum can contribute to better nutrition of the whole organism, because of its ability to produce particular vitamins from B and K groups. It can be also helpful in regulation of respiratory system functions, thanks to the reduction in histamine production and improvement in antibodies response.
Bifidobacterium bifidum contained in many complex probiotic preparations which can be found in the offer of muscle-zone.pl
What is Bifidobacterium breve?
Bifidobacterium breve is a bacterium naturally residing in the large intestine whose presence and functions have a positive effect on digestion, nutrient absorption and the overall human health. It belongs to nonspore-forming gram-positive bacteria. It is extremely resistant to gastric juices present in different parts of the digestive tract and reach the adhesion site in an adequate amount. It has been demonstrated to have a particular affinity to HT-29 cell line in the intestines.
By producing organic acids and lactic acid, it reduces the alkalinity of the intestines, hereby inducing adverse effects for the development of such pathogens as Clostridium difficile, Helicobacter pylori, E.coli and Candida. Owing to that, it reduces digestive ailments associated with bacterial infection and caused by antibiotherapy. In addition, it has a positive impact in the treatment of candidiasis.
The strains of the genus Bifidobacterium have been detected in breast milk. Owing to that, after passing through the infant’s digestive tract, it shows many benefits to its healthy development. It has an indirect impact on individuals with depression, boosts focus and concentration.
Bifidobacterium breve is found mainly in complex probiotic or symbiotic formulas available at www.muscle-zone.pl
What is Bifidobacterium longum?
Bifidobacterium longum is one of the most understood strains of probiotic bacteria naturally populating the human body. Like other bacteria of this kind, it promotes the digestion of lactose and other nutrients. Consequently, it helps absorb properly vitamins and nutrients in specific parts of the digestive tract.
Bifidobacterium longum supports the functioning of the immune system and inhibits the development of pathogens, in particular residing in the female vagina, by synthesising lactic acid, lysozyme and other acidic substances. It contributes to reducing inflammations and lowers cortisol levels. It has also the ability to produce B vitamins.
It is used in medicine in treating disorders of gastrointestinal disorders, such as nausea, constipation and diarrhoea. Due to the presence of this health-promoting strain in breast milk, the supplementation is recommended for gaining the best advantages to child development and health.
This bacteria strain is found mainly in complex probiotic or symbiotic formulas available at www.muscle-zone.pl
What is Lactobacillus acidophilus?
Lactobacillus acidophilus is a strain of rod-shaped bacteria with the ability to produce lactic acid which is beneficial to our health. These bacteria reside mainly in the intestinal mucosa. Like other probiotic strains, it can easily survive adverse conditions prevailing in specific sections of the digestive tract. As a result, it passes through the small intestine after oral administration and adheres to epithelial cells, forming small colonies. What is more, the strain was detected in the vagina, cervix and urethra. Owing to that, they can combat numerous diseases and maintain a healthy digestive and genitourinary system by competing with pathogenic microorganisms.
Apart from lactic acid production, the bacteria strain can synthesise also other organic acids which have the ability to inhibit the adhesion and proliferation of such pathogens as Escherichia coli, Staphylococcus aureus, Salmonella, Candida albicans, Shigella, Clostridium, Listeria and Helicobacter. By maintaining the normal pH in the intestines, it promotes the digestion of food and absorption of micro- and macronutrients.
It has been reported that this strain is capable of synthesising vitamin K. Consequently, it supports proper blood clotting and has a positive impact on bone structure.
By synthesising lactase, it can also promote lactose digestion, whereby treating unpleasant digestive ailments after consuming dairy products. It uses many bacteriocins for fighting pathogens, such as acidolin, acidophilin, lactobacillin, lactocin and many more.
It is applied in medicine in the treatment of food poisoning, improving the body’s immunity and treating illnesses with antibiotics. It is a component of many prebiotic, probiotic and functional formulas and various nutritional supplements available at www.muscle-zone.pl
Lactococcus lactis (formerly Streptococcus lactis) are Gram-positive bacteria, capable of conducting lactic fermentation, considered to be the so-called safe microorganisms (GRAS – generally recognizes as safe), possessing probiotic properties. They can be found in food products such as kvass, cheeses, yoghurts. In addition, they naturally occur in the human digestive system.
In addition to a beneficial effect on the gastrointestinal tract and the condition of the gut, Lactococcus lactis bacteria promote the strengthening of immunity; they may alleviate allergy symptoms and promote normal blood pressure. They also demonstrate antioxidant properties and increase the activity of endogenous antioxidant enzymes – catalase, superoxide dismutase, and glutathione peroxidase.
In supplementation, they are most often combined with other strains. They can be found in many probiotic formulas available at www.muscle-zone.pl
What is Streptococcus thermophilus?
Streptococcus thermophilus (Streptococcus salivarius) – is a kind of bacteria characterised by the ability to ferment milk, generally recognized as safe (GRAS) microorganisms It improves digestion, strengthens immunity, has anticancer and antioxidant properties. It eliminates also chlorine compounds and prevents intestinal and vaginal infections.
Streptococcus thermophilus is found mainly in complex probiotic or symbiotic formulas available at www.muscle-zone.pl
Bifidobacterium infantis – what is it?
Bifidobacterium infantis is a lactic acid bacterium present in the digestive system. It is an anaerobic bacterium, which can convert carbohydrates into lactic acid.
Bacterium is beneficial for people struggling with irritable bowel syndrome, as it reduces bloating and gas, the risk of diarrhoea and abdominal pain. B. infantis can reduce inflammations associated with particular diseases, such as psoriasis, colitis ulcerosa or chronic fatigue syndrome. What is interesting, it can quickly strengthen the intestinal barrier. Thanks to that, it contributes to the proper functioning of the immune system. It will be also helpful in case of intestinal dysbiosis, as it can fight harmful bacteria, by producing factors which will cause their death and competing over receptors in the intestinal lining to which it could attach.
Lactobacillus helveticus – what is it?
Lactobacillus helveticus are lactic acid rods which show probiotic effects, that is they bring benefits for the human body system. It is commonly used in the production of cheeses, to prevent bitterness and produce nutty flavours.
In supplements, it is used to support digestion and absorption of nutrients, raise immunity and fight pathogenic bacteria in the digestive system. It can potentially decrease blood pressure, reduce high concentration of cortisol, which is associated with stress response, and even have anticancer properties. It is believed that L. helveticus can have positive influence on general well-being. An interesting advantage is also improvement in sleep quality caused by probiotic.
Lactobacillus helveticus contained in many complex probiotic preparations which can be found in the offer of muscle-zone.pl
What is Lactobacillus salivarius?
Lactobacillus salivarius is a probiotic bacterium found mainly in the colon, small intestine and vagina, but it has been also detected in the oral cavity. It competes on populated areas with pathogens for a source of nutrients and adhesion site, hereby supporting other friendly bacteria strains in fighting pathogens. By adhering to the intestinal mucosa, it supports the intestinal barrier function. It has also a significant immunomodulatory action. It improves the balance between Th1 and Th1 helper cells in asthmatics, showing consequently an anti-inflammatory action. It inhibits the secretion of proinflammatory cytokines and supports the treatment of many skin allergies.
By producing lactic acid, bacteriocins and small amounts of hydrogen peroxide, it inhibits the growth or reduces the number of fungi of the genus Candida, E.coli, Salmonella ssp., Streptococcus pyogenes and Helicobacter pylori. Along with Bifidobacterium breve, it promotes the removal of Streptococcus mutans in the oral cavity which is responsible for tooth decay, dental plaque formation and mouth ulcers.
Promising results have been also observed in reducing pain. It results from the fact that Lactobacillus salivarius has the ability to induce the expression of receptors associated with pain relief, in particular OPRM1 in the intestines. What is more, it influences the brain-gut connection, hereby improving gut health after taking antibiotics or damaged by pathogens. As a result, it can contribute to improving cognitive functions, reducing depressive states and anxiety. It has also shown a beneficial impact on the cardiovascular system by reducing cholesterol levels and blood pressure.
Lactobacillus salivarius is found mainly in complex probiotic or symbiotic formulas available at www.muscle-zone.pl