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HI-TECH Pharmaceuticals Androdiol® is an anabolic-androgenic agent based on a clever combination of 4-androstene-3b-ol, 17-one and 5a-hydroxy Laxogenin, enabling an extremely effective and relatively safe increase in intra-organic testosterone levels.
4 androstene-3b-ol, 17-one is a steroid also known as 3β-Hydroxy-4-androsten-17-one or 4-Dehydroepiandrosterone, 4-DHEA, 4-AD or AKA; its structure resembles that of 5-Dehydroepiandrosterone (5-DHEA), distinguishing itself from a given compound only by the shift of a double bond located between the 5th and 6th carbon to a position between the 4th and 5th sterane carbon, the transfer of which differentiates certain properties of both substances.
5-DHEA is a steroid compound acting as a hormone, whose amount and potential of influencing the human body directly and indirectly, significantly exceeds other androgens. As in the case of other similar substances, cholesterol is the starting compound for its intra-organic synthesis. The dominant production sites are the reticular layer of the adrenal cortex. The testicles and ovaries seem to be less significant. The presence of 5-DHEA affects the functioning of many systems, including cardiovascular and immune systems. It also helps maintain mental balance. Its action is manifested by numerous derivatives, including: androstendione, androstenediol or testosterone. By affecting androgen receptors (AR), it initiates growth and regeneration processes in the body, including these in muscles. By inhibiting the excitability of 11β-hydroxysteroid dehydrogenase type 1 (11bHSD1), which it does independently and through androstentriol, it reduces cortisol production, thus reducing the amount of intra-organic stress and the progress of myocytes destruction caused by it. By increasing AR activity, blocking the synthesis of cortisol and modulating the response of receptors activated by peroxysome proliferators (PPAR), it improves glucose tolerance, reduces insulin resistance, improves the transport of necessary energy substrates to the cell and reduces the accumulation of fat reserves. Its performance is high, because it is an androgen not bound by sex hormone-binding globulins (SHGB). Due to its lack of susceptibility to the catalytic properties of 5α-reductase, it is not converted to aggressive 5α-dihydrotestosterone (DHT), which does not lead to adverse prostate hypertrophy. Being resistant to aromatase, as well as activating oestrogen receptors directly only to a small extent, it does not promote the occurrence of undesirable effects associated with excessive excitability of female hormones.
Similarly to 5-DHEA, 4-Dehydroepiandrosterone is a substrate for 3β-hydroxysteroid (3b-HSD) and 17β-hydroxysteroid (17b-HSD) dehydrogenases and is converted to androstendione and androstenediol respectively, which are compounds affected by 17b-HSD (androstendione) and 3b-HSD (androstenediol), which enables efficient synthesis of endogenous testosterone. Like its structural relative, it does not aromatize to oestrogens. Moreover, it shows significantly lower affinity to oestrogen receptors, which ensures significantly lower probability of possible consequences of increased activity of female hormones.
5a-hydroxy Laxogenin is also known as: Spirostan-6-one, 3-hydroxy-, (3β,5α,22ξ,25R)- and 6-Oxothigogenin, a vegetable steroid compound of the brasinosteroid group, occurring in significant concentrations in Smilax sieboldii, a evergreen corcollagen classified to the Smilacaceae family, inhabiting mainly eastern Asia, especially China and Japan.
Brassinosteroids are a group of compounds from the plant kingdom, characterized by a structure based on a control system substituted with several hydroxyl groups at the A ring of cyclopentanoperhydrophenanthrene. In the world of plants, they play mainly the role of hormones. By controlling the development of the embryo, seed germination, growth of the emerging plant, creating the ability to reproduce and participating in dying, they engage in the proper individual development of the plant and provide the possibility to extend the species. By regulating life processes, including: energy generation during photosynthesis, water management and breathing, they contribute to the proper functioning of the plant and its survival. Due to the structural similarity with some animal hormones, mainly insects, it is considered that to some extent they are able to affect selected membrane receptors in the human body, through which they cause the effects attributed to them. The most interesting feature observed is their ability to increase testosterone levels in the human body.
6-Oxothigogenin, probably by acting on appropriate prescriptions, manifests the ability to increase the pool of endogenous testosterone. As a compound not susceptible to aromatase and 5α-reductase activity, it is not converted to female hormones or DHT, and therefore does not pose a risk of overactivity.
The combination of 4 androstene-3b-ol, 17-one with 5a-hydroxy Laxogenin as two substances capable of increasing the synthesis of endogenous testosterone, provides effective activation of anabolic pathways focusing on muscle and bone tissue development and erythrocyte production. Moreover, 6-Oxotigogenin reduces the level of cortisol, intensifies the activity of thyroid hormones stimulating sluggish metabolism and improves the insulin-carbohydrate metabolism, promotes the processes of muscle building and preservation, while at the same time inhibiting the accumulation of excessive amounts of fat tissue.
Both 4-DHEA and 5a-hydroxy Laxogenin are not converted to oestrogens or DHT, and their potential direct effect on oestrogen receptors is marginal, which allows for maximum reduction of adverse effects associated with the hyperactivity of these hormones. Although, as in the case of other substances with this effect, this impact cannot be excluded, especially in sensitive individuals. Both compounds have no significant negative effect on liver condition, especially when compared to other anabolic-androgenic compounds, in particular methylated ones. Excessive portions of 4-AD may, however, lead to an increase in blood pressure, cause fatty skin or skin eczema.
The use of 4-Androstene-3b-ol, 17-one decanoate and Cyclosome™ technology, which allows for a unique closure of the desired substances, improves bioavailability and increases the effectiveness of the compounds supplied to the body.
HI-TECH Pharmaceuticals Androdiol® is a two-component anabolic-androgenic agent, promoting rapid growth of endogenous testosterone synthesis. The product contributes to the development of a substantial and aesthetic muscle mass. Its particular advantage is the low level of possible side effects, compared to other, similar, supplement.
Use for 4-6 weeks. Then take a minimum 6-week break.
The company Hi-Tech Pharmaceuticals was founded 1994 and it has grown to be a leader in the industry. It creates, manufactures and sells high-quality herbal products sold by the large, major retailers across the United States. The company has 45 supplements that develop muscle and strength, fat loss, sexual performance and healthcare. All products are aimed at improving life-quality and our supplements have unmatched in quality and efficacy. All their products are designed to improve the quality of life, and supplements are second to none in terms of quality and effectiveness. Hi-tech is a response to the needs of women and men, from active lifestyle to good sports condition. Hi-Tech Pharmaceuticals produces better products than the competition. Try it and you will not be disappointed.
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|per 1 tablet||amount||%DV|
|4-androstene-3b-ol, 17-one Decanoate||75 mg||-|
|5a-Hydroxy Laxogenin Acetate||50 mg||-|
Microcrystaline Cellulose, Phosphatidycholine 75%, Hydroxypropyl Beta cyclodextrin (HPβCD), Phytosterols, Magnesium Stearate, Silica, FD&C Blue #2, FD&C Red #40
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