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Adderex-SR Adderex-SR

HI-TECH Pharmaceuticals Adderex-SR® is a nootropic formulation based on the derivatives of phenylethylamine: β-phenylethylamine, 2- phenylethylamine and 2- phenylethane-1-amine. It is also abbreviated as PEA or β-PEA. They are, first of all, responsible for the incensement of cognitive function effectiveness and the optimization of emotional sphere.

Phenylethylamine by increasing the concentration of dopamine and serotonin, intensifies the nerve conductivity which uses them. It brings harmony both in the time of hyperactivity as well as during excessive stillness of the organism. It leads to a faster growth of the feeling of wellbeing  and reduces the sensation of anxiety and uncertainty. It gives the feeling of happiness and enjoyment. It improves the mood and promotes the positive attitude towards life. Additionally, it increases concentration, perceptive abilities and the willingness to take action.

In this supplement, a few derivatives of PEA have been applied, including: Beta-Methylphenylethylamine HCl, Beta-phenylethylamine HCl, N-methyl-phenylethylamine HCl, R-N-Benzyl-A-phenylethylamine HCl. Such solution ensures high bioavailability and stability of the given compounds, guaranteeing the effective activity of this product for a long period of time, at the same time minimizing the symptoms of “brown acid moment”, so the moment when the formulation stops to work.

Neurotransmitter’s synthesis intensification
Phenylethylamine is a compound which easily crosses the blood-brain barrier and has the role of a substrate for the synthesis of neurotransmitters. Presumably, it itself is a neurotransmitter. Through interaction with specific receptors, which are responsible for the excitability of selected hormones, it significantly influences the effectiveness of cognitive processes and the formation of the emotional sphere. PEA, being the antagonist of trace amine receptors (TAAR or TA), especially TA1, it interferes in the functionality of monoamine transponders, which decreases the reuptake of dopamine, serotonin and noradrenaline, leading to the alleviation of their levels in the synapses.

It is also considered as a partially allosteric antagonist of β-adrenergic receptors, mainly β1 and β2, and as a less important antagonist of α-adrenergic receptors. It is believed that the effects observed after its application are resulting mainly form the ability to increase the concentrations of dopamine and serotonin, and therefore activity amplification of these hormones.

Dopamine, aka 3,4-hydroxyethylamine or prolactostatin is a dominant catecholamine in the human brain, which contains approximately 80% of all the compounds in this group. Structurally it is similar to 2-phenylehylamine, with the main difference being the fact that is possesses two hydroxyl groups, directly attached to the benezene ring in the position 3’ and 4’. It is synthesized mainly in by the dopaminergic neurons from L-phenylamine, or L-tyrosine, or L-DOPA (levodopa, L-3,4-dihydroxyphenylalanine) to dopamine. In this process the following take part: phenylalanine hydroxylase, tyrosine hydroxylase and decarboxylase of aromatic L-amino acids. It exhibits its excitability via two families of dopaminergic receptors. One of them is the D1 family, among which one can find D1 and D5 receptors, the second however, is the D2 family, gathering D2, D3 and D4 receptors.

It influences the human organism mainly by dopaminergic systems, among which the most important ones are: black matter – striatum system, regulating the motor functions and mesocorticolimbic system, divided into mesocrine and mesolimbic system. First of them is responsible for the thought processes and remembering, whereas the second one supervises the emotional sphere and motivation. Therefore, its activity as a neurotransmitter allows for the planning and realization of motor actions, ensures the maintenance of required muscle efficiency, supports the learning ability, promotes the feeling of happiness and enjoyment and motivates to take action. What is more, it involved in normalizing the level of many hormones, including: prolactin, thyrotropin, growth hormone and gonadotropins. Most often, however, it is ascribed with the highest role in decreasing the production of prolactin and increasing the secretion of growth hormone. It is important for maintaining the proper blood pressure and proper functioning of the kidneys.

Serotonin, also known as 5-hydroxytryptamine, 5-HT in short, is a substance belonging to tryptamines. Under the form of neurotransmitter, or hormone, it exhibits a wide spectrum of actions over the human organism. Its structure is based on the indole ring. 95% of its production is carried out in the gastrointestinal tract. The other part comes from the central and peripheral nervous system, immunological system and cell that secrete melatonin. A precursor to its synthesis is L-tryptophan, which after the transformation into 5-hydroxytryptophan, converts to serotonin, with the use of tryptophan hydroxylase and 5-hydroxytryptophane decarboxylase subsequently.

Its activity is most profoundly noticed in the nervous system, both in central and in the peripheral, but in gastrointestinal, muscular and circulatory systems as well. It is responsible for the proper sensory experience of pain and is involved in the occurrence of the thought processes and memory formation. It promotes the feeling of happiness and improves the mood, by reducing the aggression and obsession level. It participates in the regulation of circadian rhythm of the organism. What is interesting, it influences the emotional sphere to such an extent that it can contribute to the occurrence of falling in love. It is also responsible for the feeling of sexual drive. Additionally, it promotes smooth muscles contractions and allows for the proper functioning of gastrointestinal system. Its concentration is also connected with the regulation of hunger.

To sum up, HI-TECH Pharmaceuticals Adderex-SR is a nootropic product that contains several forms of phenylethylamine, a compound with psychoactive effects. It helps to introduce the good mood, it ensures a mental wellbeing, and at the same time it improves concentration and enhances the cognitive abilities. By doing so, it increases the effectiveness of the performed activities while keeping the good attitude towards life and performed activities.

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Since 2005
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Adderex-SR Adderex-SR 60 tab.
Hi-tech
42.94 $

Adderex-SR 60 tab.

features

Strength:
Mass:
Endurance:
Concentration:

- Delivery even day after tomorrow

- Foreign shippment from 5.57 $ Every 81.03 $ reduces shipping costs by 2.70 $

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sales@mz-store.co.uk

01709231594 (mon.-fri 900-1700)

42.94 $
Notify me of availability

- Delivery even day after tomorrow

- Foreign shippment from 5.57 $ Every 81.03 $ reduces shipping costs by 2.70 $

You have got questions about the product

sales@mz-store.co.uk

01709231594 (mon.-fri 900-1700)

Description
  • It is an effective antagonist of TAAR1 receptors
  • Possess high bioavailability and efficacy
  • Gives the will to live and take action
  • Supports the mental and emotional sphere
  • Lowers the feeling of anxiety and uncertainty
  • Increases the level of dopamine and serotonin
  • Focuses in itself several phenylethylamine forms
  • Gives the sensation of happiness and wellbeing
  • Improves brain functioning
  • Supports the cognitive processes
  • Increases the concentration

HI-TECH Pharmaceuticals Adderex-SR® is a nootropic formulation based on the derivatives of phenylethylamine: β-phenylethylamine, 2- phenylethylamine and 2- phenylethane-1-amine. It is also abbreviated as PEA or β-PEA. They are, first of all, responsible for the incensement of cognitive function effectiveness and the optimization of emotional sphere.

Phenylethylamine by increasing the concentration of dopamine and serotonin, intensifies the nerve conductivity which uses them. It brings harmony both in the time of hyperactivity as well as during excessive stillness of the organism. It leads to a faster growth of the feeling of wellbeing  and reduces the sensation of anxiety and uncertainty. It gives the feeling of happiness and enjoyment. It improves the mood and promotes the positive attitude towards life. Additionally, it increases concentration, perceptive abilities and the willingness to take action.

In this supplement, a few derivatives of PEA have been applied, including: Beta-Methylphenylethylamine HCl, Beta-phenylethylamine HCl, N-methyl-phenylethylamine HCl, R-N-Benzyl-A-phenylethylamine HCl. Such solution ensures high bioavailability and stability of the given compounds, guaranteeing the effective activity of this product for a long period of time, at the same time minimizing the symptoms of “brown acid moment”, so the moment when the formulation stops to work.

Neurotransmitter’s synthesis intensification
Phenylethylamine is a compound which easily crosses the blood-brain barrier and has the role of a substrate for the synthesis of neurotransmitters. Presumably, it itself is a neurotransmitter. Through interaction with specific receptors, which are responsible for the excitability of selected hormones, it significantly influences the effectiveness of cognitive processes and the formation of the emotional sphere. PEA, being the antagonist of trace amine receptors (TAAR or TA), especially TA1, it interferes in the functionality of monoamine transponders, which decreases the reuptake of dopamine, serotonin and noradrenaline, leading to the alleviation of their levels in the synapses.

It is also considered as a partially allosteric antagonist of β-adrenergic receptors, mainly β1 and β2, and as a less important antagonist of α-adrenergic receptors. It is believed that the effects observed after its application are resulting mainly form the ability to increase the concentrations of dopamine and serotonin, and therefore activity amplification of these hormones.

Dopamine, aka 3,4-hydroxyethylamine or prolactostatin is a dominant catecholamine in the human brain, which contains approximately 80% of all the compounds in this group. Structurally it is similar to 2-phenylehylamine, with the main difference being the fact that is possesses two hydroxyl groups, directly attached to the benezene ring in the position 3’ and 4’. It is synthesized mainly in by the dopaminergic neurons from L-phenylamine, or L-tyrosine, or L-DOPA (levodopa, L-3,4-dihydroxyphenylalanine) to dopamine. In this process the following take part: phenylalanine hydroxylase, tyrosine hydroxylase and decarboxylase of aromatic L-amino acids. It exhibits its excitability via two families of dopaminergic receptors. One of them is the D1 family, among which one can find D1 and D5 receptors, the second however, is the D2 family, gathering D2, D3 and D4 receptors.

It influences the human organism mainly by dopaminergic systems, among which the most important ones are: black matter – striatum system, regulating the motor functions and mesocorticolimbic system, divided into mesocrine and mesolimbic system. First of them is responsible for the thought processes and remembering, whereas the second one supervises the emotional sphere and motivation. Therefore, its activity as a neurotransmitter allows for the planning and realization of motor actions, ensures the maintenance of required muscle efficiency, supports the learning ability, promotes the feeling of happiness and enjoyment and motivates to take action. What is more, it involved in normalizing the level of many hormones, including: prolactin, thyrotropin, growth hormone and gonadotropins. Most often, however, it is ascribed with the highest role in decreasing the production of prolactin and increasing the secretion of growth hormone. It is important for maintaining the proper blood pressure and proper functioning of the kidneys.

Serotonin, also known as 5-hydroxytryptamine, 5-HT in short, is a substance belonging to tryptamines. Under the form of neurotransmitter, or hormone, it exhibits a wide spectrum of actions over the human organism. Its structure is based on the indole ring. 95% of its production is carried out in the gastrointestinal tract. The other part comes from the central and peripheral nervous system, immunological system and cell that secrete melatonin. A precursor to its synthesis is L-tryptophan, which after the transformation into 5-hydroxytryptophan, converts to serotonin, with the use of tryptophan hydroxylase and 5-hydroxytryptophane decarboxylase subsequently.

Its activity is most profoundly noticed in the nervous system, both in central and in the peripheral, but in gastrointestinal, muscular and circulatory systems as well. It is responsible for the proper sensory experience of pain and is involved in the occurrence of the thought processes and memory formation. It promotes the feeling of happiness and improves the mood, by reducing the aggression and obsession level. It participates in the regulation of circadian rhythm of the organism. What is interesting, it influences the emotional sphere to such an extent that it can contribute to the occurrence of falling in love. It is also responsible for the feeling of sexual drive. Additionally, it promotes smooth muscles contractions and allows for the proper functioning of gastrointestinal system. Its concentration is also connected with the regulation of hunger.

To sum up, HI-TECH Pharmaceuticals Adderex-SR is a nootropic product that contains several forms of phenylethylamine, a compound with psychoactive effects. It helps to introduce the good mood, it ensures a mental wellbeing, and at the same time it improves concentration and enhances the cognitive abilities. By doing so, it increases the effectiveness of the performed activities while keeping the good attitude towards life and performed activities.

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Composition

Composition

Container size: 60 tabletsServing size: 1 tabletServings per container: 60
per 1 tabletamount%DV
Proprietary Blend:Beta-methylphenylethylamine HCl, Beta-Phenylethylamine HCl, N-methyl-phenylethylamine HCl, R-N-Benzyl-A-Phenylethylamine HCl, L-lysine/Beta-methylphenylethylamine HCl, L-lysine/Beta-phenylethylamine HCl275 mg-

Other ingrednients

Dextrose, Microcrystalline Cellulose, Stearic Acid, Magnesium Stearate, Sodium Starch Glycolate, Starch, Triacetin, Titanium Dioxide, Silica, FD&C Red #3, FD&C Yellow #6

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Proprietary blend

Information

Proprietary blend - is a complex of bioactive ingredients in the proportions, which are covered by the manufacturer's patent. According to the law in force in Poland, the components of the blend are known, and , by the place on the packaging, you can identify which components are in bigger amount (the components are listed in the decreasing order of amounts).
Proprietary blends are used in many food supplements, such as creatine stacks, no-boosters, fat burners and pro-testosterone supplements, improving libido.


 

Lysine

Information

Lysine belongs to the group of 9 essential amino acids delivered into the body from outside (with food or as a supplement) .It is a building substance of protein (the muscle protein). It is available in food of animal origin (meat, dairy products) and vegetable (legumes). It plays an important role in many physiological processes (absorption of calcium, production of enzymes, hormones and antibodies), and arginine is a component of supplements that increase the synthesis of growth hormone (HGH stimulators). In the form of hydroxylysine (a component of collagen) recommended for the treatment of sports injuries, and prevention. In the case of stress and excessive physical and psychological overloads, it is recommended due to the function of lowering cortisol levels. Also it applies in medicine, in the treatment of anxiety and herpes. The share of lysine intake of daily doses of amino acids should not exceed 5.1%. Available for purchase at www.muscle-zone.pl.
In the processes of digestion of protein matter, as a result of decarboxylation of lysine, may be converted into cadaverine (biogenic amine) having a strong toxicity.
Dosage: the lack of a well-defined standard daily intake of lysine. The supplementation dosages regularly used: with arginine 500 mg - 2g (before bedtime) pre- and post-workout optionally with other amino acids.

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