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Blackstone Labs APEX MALE is a product belonging to the group of testosterone boosters, used also as a means in Post Cycle Therapy (PCT). By a multidirectional support of autosomal synthesis of testosterone and its protection from unfavorable transformations to dihydrotestosterone and estrogens, in allows to produce a high level of natural testosterone in the system. By creating an optimal hormonal environment and at the same time improving the process of spermatogenesis, erection and libido, it is conducive to maintaining plentitude of vigor and high sexual performance. Moreover, by taking care of the correct functioning of numerous systems, including cardiovascular, nervous or immune systems, it completes the whole guaranteeing the highest functionality of a male organism.
Blackstone Labs APEX MALE contains the following ingredients:
APEX MALE BLEND:
Bulbine natalensis extract - an essence derived from Bulbine natalensis, a plant classified to the Asphodelaceae family, which does not have spines, blooms in yellow color of succulent overgrowing hot regions of Africa. The properties demonstrated by this plant are mainly attributed to the richness of the appropriate: alkaloids, saponins, tannins and cardiac glycosides. It primarily exhibits strongly visible aphrodisiac effects. By increasing the level the luteinizing hormone (LH) and at the same time by stimulating the synthesis of endogenous testosterone, it promotes shaping male features and behaviors and intensifies anabolic processes in the system. By increasing the production of the follicle stimulating hormone (FSH), it escalates the effectiveness of spermatogenesis, which is responsible for the reproduction capacity of men. By increasing the storage of nutrients in the form of protein and glycogen in testicles, it ensures appropriate production possibilities. Thanks to increasing FSH concentration, it promotes the creation of sex hormone binding globulins (SHBG), which by binding a certain part of testosterone circulating in the system protect them from unfavorable transformations, including aromatization to estrogens. It is conducive to lowering excessively inflated amounts of estrogen. By creating appropriate hormonal environment, intensifying spermatogenesis, increasing libido and supporting evoking and maintaining erection, it enables the increase of sexual satisfaction. By shortening the time of fibroblasts differentiation, as well as accelerating the development of collagen, it improves the state of collagen structures. It also has antibacterial properties. The application of the extract signed with the mark ProLensisTM ensures the guarantee of effectiveness and effects supported by research.
Diindolylmethane – in short DIM, an aromatic chemical compound being an indole derivative, naturally developed in the human system, in acidic stomach environment by dimerization of indole-3-carbinol (I3C). It is assumed, that the effects of a given compound are caused mainly thanks to the ability to interfere with the activity of aromatic hydrocarbon receptors (AhR), estrogen and androgen receptors in the specific areas of the system. By affecting AhR receptors it increases the effectiveness of NK cells and increases the production of gamma-interferon (IFN-γ), improving at the same time the functions of the immune system. By competing stronger with estrogenic compounds for the access to the desired receptors, it diminishes the estrogenic potential of the organism, causing antiestrogen effect. By influencing androgen and estrogen receptors excitability in the area of prostate, it reduces the excessive activity of dihydrotestosterone (DHT) and estrogens in that area, diminishing by the same token the development of unfavorable cell changes taking place in the prostate.
Fenugreek extract – an extract most often derived from the seeds of Trigonella foenum-graecum, a plant classified to the Fabaceae family, coming from the terrains of Eastern Europe and Asia, then spread around and willingly cultivated in other regions of the World. Trigonelline – methylated niacin derivative is claimed to be the most important active substance of the plant. By directly activating androgen receptors, it initiates the growth of muscle structures. By lowering 5-α-reductase excitability, it decreases the pace of free testosterone transformations to dihydrotestosterone (DHT), limiting at the same time the activity of androgen receptors in the area of prostate. By increasing libido, it improves sexual performance and increases sexual satisfaction. By increasing the concentration of triiodothyronine (T3) and thyroxine (T4), it stimulates energy substrates metabolism, promotes their burning and reduces their storage. By counteracting pancreas cells damages and improving insulin burst in the presence of glucose, it engages in the proper functioning of insulin-carbohydrate metabolism. By stimulating the activity of PI3K, it facilitates glucose uptake by muscle cells, thanks to which it lowers the level of insulin-resistance of the system, improves glucose tolerance and increases productivity of the processes responsible for glycogen storage. By optimizing carbohydrate balance, it limits the occurrence of excessive glucose spikes in blood. By influencing the size of appetite, it decreases the feeling of hunger, especially regarding high-fat products. By lowering cholesterol and bile acids absorption from the digestive system, it supports maintaining proper lipid profile. By influencing the serotoninergic system, it reduces the feeling of pain. By increasing the functioning effectiveness of the antioxidant barrier by the growth of antioxidant enzymes activity, it reduces the size of oxidative damages in the liver, which is conducive to maintaining proper condition of the organ.
Tribulus terrestris extract – a product created as a result of the ground-based elements extraction of Tribulus terrestris, a small shrub from the Zygophyllaceae family, which as a weed overgrows warm regions of Western Asia, Africa, Australia and Europe. Extraordinary properties presented by this plant are attributed to the high content of steroid glycosides, also called saponins. They increase, previously decreased amount of hormones, mainly luteinizing and testosterone, up to the natural level, they normalize processes taking place in the human organism and increases vitality, especially in men. By increasing the concentration of 3',5'-cyclic adenosine monophosphate (cAMP), influencing the amount of 3',5'-cyclic guanosine monophosphate (cGMP) and improving NO/NOS signalization, it conduces smooth muscles relaxation, located in corpus cavernosum, increasing by the same token blood influx to their insides, which facilitates evoking and maintaining erection. It increases the effectiveness of the processes responsible for the creation and maturation of sperm cells. By supporting erection, it improves libido and ensures better efficiency of the spermatogenesis process, increases sexual satisfaction and increases the effectiveness of procreation. By increasing the activity of superoxide dismutase (SOD) and reducing the size of fats stored in the liver, it improves the state of this organ. By reducing the excitability of glucose oxidase (GOX) and demonstrating a certain diuretic effect, it lowers the probability of stone creation in the urinary system. By supporting the synthesis of endothelial nitric oxide and exhibiting diuretic properties, it contributes to maintaining proper blood pressure. By exerting diastolic effects in coronary vessels, it increases blood flow to many organs located in the organism. By lowering the level of triglycerides, total cholesterol, low-density lipoproteins (LDL) and very low-density lipoprotein (VLDL) and by increasing the concentration of high-density lipoproteins (HDL), it optimizes lipid profile. By normalizing lipid profile and reducing the level of glucose in the bloodstream, it minimized the level of stored reserves in fatty tissue. By intensifying non-specific immune response, it improves the effectiveness the immune system functions. By limiting proliferation of improperly altered cells and inducing their degradation by lowering the activity of NF-ĸB, it slows down the development of carcinogenic processes. By inhibiting monoamine oxidase, it increases dopamine concentration, as a result of which it ensures well-being. By decreasing the synthesis of: cyclooxygenase-2 (COX-2), inducible nitric oxide synthase (iNOS) and proinflammatory cytokines, including IL-4 and TNF –α, it evokes an anti-inflammatory effect. It also reduces the level of pain, counteracts bacteria, larva and worms.
D-Aspartic Acid – shortened as DDA, nitric chemical compound from the group of amino acids, being a non-proteinogenic enantiomer of aspartic acid, whose biological activity is mainly noticeable in the area of the central nervous system. A vast majority of effects attributed to this acid presented by itself or mediated by its methylated derivative, N-Methyl-D-aspartate (NMDA), is demonstrated by the influence on NMDA receptors. By affecting the receptors located in the area of hippocampus, it improves mental and memory processes. By affecting given receptors, it stimulates nerve conductivity and conduces increased organism activity. By participating in normalizing neurogenesis, it ensures proper development and functioning of the nervous system. By creating the quality of steroidogenic acute regulatory protein (STAR) and quickening the creation of luteinizing hormone (LH) responsible for initiating testosterone production in Leydig cells, it increases the concentration of testosterone in the system. By intensifying the synthesis of follicle stimulating hormone (FSH), it increases the level of sex hormone binding globulins (SHBG), securing excessively produced amounts of testosterone from unwanted aromatization to other steroid compounds, including estrogens. As a result of the increase of FSH concentration, it accelerates the production and development of sperm cells. By increasing the efficiency of spermatogenesis and ensuring higher sperm cells mobility, it increases reproductive possibilities of men. By intensifying anabolic hormones synthesis, especially testosterone and growth hormone (GH), it accelerates the pace of anabolic processes in the system.
MACA extract – i.e. Lepidium meyenii extract, a species of plants classified to the Brassicaceae family, having a dozen varieties different in coloration, which in the form of herbs overgrows alpine, central regions of Peruvian Andes. MACA made in a traditional way constitutes a compilation of several variations of the species, which allows to highlight the whole range of herb’s properties. It is known primarily as a means enhancing sexual drive and supporting evoking and maintaining erection. By accelerating mitotic divisions in the process of sperm cells creations, it increases spermatogenesis efficiency. By increasing libido, facilitating erection, accelerating sperm cells production and at the same time increasing their mobility, it multiplies reproduction possibilities. It limits benign prostatic hyperplasia without interfering with testosterone or estradiol concentration. By inhibiting the unfavorable process of lipids oxygenation and minimizing the development of excessive oxidation processes taking place in the brain, it exerts neuroprotective effect. By maintaining good condition of the nervous system and minimal acetylcholinesterase activity, while preserving the required excitability of monoamine oxidase, it improves the cognition and memory processes. It lowers the feeling of anxiety and depression. By facilitating insulin secretion, with the simultaneous improvement of glucose tolerance, it normalizes the amount of sugar circulating in blood. It improves lipid profile. By providing large amounts of potassium and inhibiting catalytic activity of angiotensin convertase (ACE), it supports maintaining optimal blood pressure.
Prunella vulgaris extract – an essence derived from Prunella vurgaris, a flowering herb classified to the Lamiaceae family, a perennial plant fond of temperate climate, overgrowing mostly humid, shaded and alkaline or neutral soils of the north hemisphere of the globe, deployed on the European and Asian continents as well as in North America. It derives its properties from the whole spectrum of chemical compounds among which the most often enumerated are organic acids, including: betulinic, rosemary, oleanolic, caffeic or chlorogenic acids. By inhibiting estrogen activity by regulating the response of aromatic hydrocarbons receptors (AhR), it has an antiestrogen effect. By blocking replication of certain viruses and counteracting their bonding and cell penetration, it shows antivirus effects. By providing proper antioxidant compounds, it increases the efficiency of antioxidant barrier. It stimulates lymphocytes T proliferation, by inhibiting the synthesis of excessive amounts of nitrogen oxide (NO) and reducing the activity of the ROS/NF-kB pathway, it limits the size of inflammations. It demonstrates moderate antibacterial effect. By intensifying the activity of macrophages to phagocytosis, synthesis NO and showing cytostatic effect, it improves non-specific response of the immune system. By limiting the size of mutations and minimizing proliferation of unfavorable cells, it restricts the development of dangerous cell changes. By intensifying endothelial nitric oxide synthase (eNOS) responsible for producing endothelial NO, it improves the state of vessels and at the same time the efficiency of the cardiovascular system. By slowing down histamine release, it exerts ant-allergic effect. By inhibiting sudden increase of glucose in blood regardless of insulin and reducing the size of inflammations in the pancreas, it supports the functioning of a given organ and the whole insulin-carbohydrate metabolism.
Epimedium extract – extract from a plant also known as Horny Goat Weed or Yin Yang Huo, a perennial plant overgrowing the terrains of Asia, mainly China. One of the most important active components of the plant is icariin, a flavonoid compound, being a derivative of kaempferol 3,7-diglucoside. It demonstrated strong aphrodisiac effects. By exhibiting testosterone mimetic properties and at the same time increasing the level of free testosterone without engaging luteinizing hormone (LH), it improves men’s efficiency. By intensifying neuronal nitric oxide synthase (nNOS), increasing the durability of cyclic guanosine monophosphate (cGMP) by inhibiting phosphodiesterase type 5 (PDE 5) and accelerating cGMP transformation into guanosine monophosphate (GNP), it improves blood flow to the penis and conduces maintaining it in a given area of the body, which allows better effectiveness in evoking erection. By intensifying the expression of endothelial nitric oxide synthase (eNOS), it increases the pace of nitric oxide synthesis (NO), leading to vessels relaxation and at the same time the improvement of the cardiovascular system functions. By decreasing endothelial cells breakdown by reducing the excitability of caspase-3 and by lowering the amount of homocysteine thanks to decreasing the activity of S-adenosyl-L-homocysteine hydrolase (SAH), it allows to maintain good condition of the cardiovascular system. By supporting the production of osteoblasts intensifying the regeneration pace of the bone structure and decreasing inflammation states in the area of joints and bones by slowing down the activity of NF-kappaB with simultaneous increase of IkappaBalpha activity, it supports maintaining good condition of the osteoarticular system.
L-tyrosine – also noted as 2-Amino-3-(4-hydroxyphenyl)propanoic acid or in short Tyr or Y, an endogenous aromatic amino acid produced naturally in the human system from L- phenylalanine with the utilization of phenylalanine hydroxylase. By constituting an indispensable part of protein structures, it engages in building given biopolymers, including muscle tissue, hormones and enzymes. Being a starting compound to the synthesis of thyroid hormones, including triiodothyronines (T3) and tetraiodothyronines (T4), it takes part in metabolic transformations, changing energy substrates into energy and in rationalization of stored energy substrates in the form of glycogen and fat. As a substance both glucogenic and ketogenic, when necessary it powers the reservoir of energy substrates, earlier undergoing transformation to glucose or ketone bodies. Occurring in the role of catecholamine substrate, among others dopamine, adrenaline and noradrenaline; it takes part in neurotransmission, influencing our mood and the activity of our organism. By enabling adrenaline synthesis, it supports the survival of the organism in extremely stressful situations. By taking part in catecholamine production, it ensures proper functionality of many systems, especially cardiovascular and digestive systems.
Piper nigrum extract – properly prepared Piper nigrum fruit extract, a climbing shrub classified to the Piperaceae family, occurring naturally on the terrain of India, cultivated in hot areas of the globe, mostly in China and Malay Archipelago and Peninsula. Piperidine, is believed to be the most important active compound of the plant, which is a secondary cyclical amine responsible for evoking the feeling of stinging after eating fruit rich in it. By stimulating protease production and secretion of stomach acid to the stomach, it increases the effectiveness of digestion of protein food. By improving blood circulation, enabling blood flow into the lowest parts of the digestive system and by intensifying nutrients transport from intestinal lumen to the inside of the system, it intensifies the assimilation of amino acids, carbohydrates, minerals, the most effectively selenium, vitamins, especially group B and numerous compounds supporting proper functioning of the organism, among others beta-carotene, curcuma, resveratrol and coenzyme Q10. By supporting the storage of beneficial substances in the cells of the system, it increases the effectiveness of their activity in the target regions of the system. By exhibiting antioxidant effects, it increases the infallibility of the antioxidant barrier. By inhibiting interleukin 6 synthesis (IL6) and prostaglandins E2 (PGE 2), it reduces developing inflammatory cells and exhibits analgesic effect. By positively influencing the level of earlier depressed hormones, among others testosterone, triiodothyronines (T3) and tetraiodothyronines (T4), it normalizes the processes taking part in the organism. By interfering with the work of the serotonergic system, it decreases stress, introducing mental well-being. By creating proper thyroid hormones concentration and increasing the level of 3',5'-cyclic adenosine monophosphate (cAMP), it supports organism’s energy and improves body composition. By activating MC-4 receptors and influencing apolipoprotein concentration and the excitability of lecithin-cholesterol acyltransferase and lipoprotein lipase, it reduces the number of triglycerides, total cholesterol, low-density lipoproteins and very low-density lipoproteins (LDL and VLDL) and increases the level of high-density lipoproteins (HDL), thanks to which it shapes a beneficial lipid profile. By lowering the activity of collagenase MMP13, it minimizes the destruction of collagen structures type II, enabling the maintenance of good condition of joints. By lowering the development of the processes responsible for collagen breakdown and improving skin pigmentation, it supports maintaining a satisfying skin condition. Signing this extract with Bioperine® mark constitutes a guarantee of its effectiveness which is reflected in scientific studies, a guarantor of which is the company Sabinsa, a valued producer and distributor of plant extracts on an international scale.
Blackstone Labs APEX MALE is an effective testosterone booster with extended effects, finding its application also as a great PCT means. By increasing the level of luteinizing hormone (LH), it maximizes autosomal synthesis of natural testosterone. Thanks to the increased number of sex hormones binding globulins (SHBG), limiting the catalytic power of aromatase and 5a-reductase, it secures testosterone from its excessive transformations into sex hormones. By normalizing the processes of testosterone derivatives creation and limiting the response of estrogen and androgen receptors in certain regions of the system, it shapes more male attitude towards life with simultaneous limiting of side effects caused by excessively inflated sex hormones concentration. By increasing the amount and mobility of sperm cells, it supports maintaining high reproductive possibilities. By demonstrating aphrodisiac effect, increasing libido and promoting evoking and maintaining erection, it ensures full satisfaction from a sexual intercourse. By intensifying anabolic processes taking part in muscle tissue and facilitating the functioning of insulin-carbohydrates and fat metabolism, it is conducive to the creation of athletic silhouette. Moreover, by engaging in maintaining good state of many systems: including cardiovascular, nervous, osteoarticular or immune systems, it ensures maintaining good condition and functionality of the whole organism.
As a natural testosterone booster, the preparation does not require periodic use or PCT (post-cycle therapy).
With age, endogenous testosterone production gradually decreases. That is why the product is particularly recommended for men in their 30s and older.
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|per portion (4 capsules)||amount||%DV|
|Vitamin D3 (as Cholecalciferol)||1250 IU||313%|
|D-aspartic Acid||1500 mg||-|
|Bulbine Natalensis (Prolensis)||500 mg||-|
|Fenugreek Extract (Seed) (std. to 50% Saponins)||125 mg||-|
|Tribulus Terrestris (std. to 40% Saponins)||125 mg||-|
|Maca Extract (Lepidium meyenii) (root) (std. 0.6% Macamides and Macaenes)||125 mg||-|
|DIM (Diindolylmethane)||100 mg||-|
|Prunella Vulgaris (Whole Plant)||75 mg||-|
|Epimedium Extract (Aerial Parts/Leaf)||75 mg||-|
|N-methyl D-aspartate||15 mg||-|
|Bioperine (Black Pepper Fruit Extract)||5 mg||-|
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