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Flush-Free Niacin is a dietary supplement that contains vitamin B3 in the form of inositol hexanicotinate It is a special form of vitamin B3 which helps to preserve all its benefits for the body without the so-called flushing effect, which is characterised by reddening and tingling of the skin that occurs often after the intake vitamin B3 as nicotinic acid.
Vitamin B3 (niacin) — is a common name used to refer to two compounds: nicotinic acid (the so-called niacin) and amide nicotinamide (the so-called niacinamide). Since it prevents the dangerous disease called pellagra, vitamin B3 is often called vitamin PP (pellagra-preventive).
There is a special form of vitamin B3 in supplementation — inositol hexanicotinate. It is a form of nicotinic acid, hydrolysed in the body to nicotinic acid and inositol. It is released much longer than other standard forms of niacin, consequently preventing unpleasant symptoms known as “niacin flush” (“flushing”). This is a temporary, short-term reaction that occurs after taking vitamin B3. It appears as flushing of the face, itching and tingling and in rare cases headaches. This is not dangerous for health. However, it is so unpleasant that some people quit the supplementation of vitamin B3. The solution is the use of niacin in the form of.inositol hexanicotinate.
Vitamin B3 can be synthesised in the body from the amino acid called tryptophan. Nevertheless, these amounts are not sufficient to meet the body’s requirements. Furthermore, tryptophan belongs to indispensible amino acids which must be delivered exogenously to the body. Too small supply will result in secondary niacin deficiency.
Vitamin B3 deficiency is often caused by poor diet, alcohol abuse and less frequently by malabsorption and the administration of anticonvulsants. Excess amounts of niacin are excreted in urine and that is why it is quite difficult to overdose it. However, deficiency may be dangerous for your health.
The regulation of cholesterol levels
The proper functioning of the circulatory system depends largely on the balance between “good” (HDL) and “bad” (LDL) cholesterol. Low density lipoprotein (LDL cholesterol) tends to deposit on the arterial walls in the form of build-ups which can cause heart attack or stroke by clogging the arteries. Vitamin B3 shows exceptional anticholesterol properties — as one of few substances, it lowers LDL and triglyceride levels, while increasing at the same time HDL levels. The studies show that niacin in the form of inositol hexanicotinate exhibits there the highest efficacy. Because of gradual release and absorption, it does not overload the liver and its anticholesterol action is longer than in the case of nicotinic acid. The treatment with niacin effectively reduces the incidence of cardiovascular diseases and stroke.
Benefits for the nervous system
Niacin stabilises the nervous system — calms, soothes, promotes relaxation and helps fall asleep. It is involved in the synthesis of serotonin from tryptophan. Serotonin is one of the most important neurotransmitters which is a prerequisite for a good mood and correct cognitive functions. Niacin deficiency is frequently manifested by insomnia and anxiety. Vitamin B3 is sometimes used in the treatment of mental disorders and schizophrenia. There are also studies that confirm its efficacy in treating depression.
Vitamin B3 is one of the most important biosubstances affecting the process of cellular energy production. It acts as an acceptor and donor of hydrogen ions in a number of biological reactions, participates in the metabolism of proteins, carbohydrates and fats. It is also a constituent of two significant coenzymes — NAD and NADP which have a crucial role in cellular respiration. Niacin deficiency is frequently manifested by weakness and the lack of energy. It can also deteriorate gastrointestinal health, especially in the stomach and intestines.
Support for detoxification
The body’s effective detoxification process is essential for maintaining health. Niacin helps to eliminate heavy metals from the body and inhibits toxic effects of chemical compounds and pharmacological agents. It promotes the metabolism of ethylene alcohol — it would not be possible without this vitamin to break down its molecules. Otherwise, this could thus significantly overload the liver and damage its cells.
Vitamin B3 shows high effectiveness in eliminating Candida and ascomycota, including Aspergillus responsible for otomycosis, pulmonary aspergillosis and asthma. It inhibits the growth of fungi and yeast by blocking the enzyme deacetylase (Hst3p) which is essential to the development of fungi. Experts believe that the effectiveness of the treatment in the case of Candida hypertrophy and yeast infections is comparable to popular pharmacological agents. However, it does not cause any side effects.
Vitamin B3 for women
Women of childbearing age naturally have higher requirements for vitamin B3 because estrogens inhibit the conversion of tryptophan into this vitamin. Supplementation is recommended to women also because of positive effects of niacin on the female endocrine system and the condition of the skin and hair.
Niacin helps maintain a proper condition of the skin and hair. It improves skin tone, eliminates redness and roughness. It prevents hair loss and helps get rid of severe dandruff.
Vitamin B3 regulates the levels of female hormones — estrogen and progesterone so that it aids in controlling the menstrual cycle and reduces menstrual pain.
The supplement Flush-Free Niacin is a perfect method for correcting vitamin B3 deficiency. It contain an optimum dose of niacin in the form of inositol hexanicotinate. This form of vitamin B3 effectively protects you from the unpleasant “niacin flush” and retains all properties beneficial to the body.
Niacin can be taken with or without food. When discomfort or gastrointestinal disorders occur, it is advisable to take it with a meal to prevent these ailments.
A proper niacin dose is determined according to age, sex, physiological condition and accompanying disorders. The recommended daily niacin intake ranges from 20 to 40 mg. This dose can be effective as a part of prevention of diet-related diseases, but it can be too small for obtaining a therapeutic effect. For instance, it is said that a higher dose is required for regulating the lipid profile – 750-1000 mg of vitamin B6 a day.
Now Foods is a company with years of experience in the industry that offers a wide range of nutrients and dietary supplements. Brand is known for its high-quality products designed for hair and nails and supplements supporting the immune system. The offer includes the antioxidant supplements, antibacterial supplements, reducing appetite supplements, products supporting the reduction of body fat and improving digestion. All products are made from natural ingredients.
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Cellulose (capsule), Stearic Acid (vegetable source), Magnesium Stearate (vegetable source), Rice Flour and Silica.
Inositol is an organic compound from the group of B vitamins soluble in fluids, present in the natural or synthetic form, synthesized in plants, such as brewer's yeast, beans, grapefruit, cabbage, sprout of wheat, melons and animal (liver). Along with choline is included in the lecithin. It affects the cell nutrition of the central nervous system (brain) by reducing the level of LDL (bad cholesterol), this makes it applicable in treatment of Alzheimer's disease and atherosclerosis. It has a calming effect. There has been a beneficial effect of inositol on the skin and hair reported.