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Cholecalciferol – a form of vitamin D, called vitamin D3. It is fat-soluble and can be stored in the organism. Most cells in the human body have vitamin-D-specific receptors called VDR. It has a very wide range of effects on the functioning of the entire organism; it is also the most deficient nutrient.
Vitamin D is known for being produced mainly in summer when rays of sun reach our skin surface. In that case, can we be sure that in summer we have enough vitamin D? No. That’s because cholecalciferol synthesis is induced by UV-B rays emitted only at noon, more or less between 11 a.m. and 2 p.m. Most people spend that time at work or carrying out chores, and even when they go outside, most skin surface is covered with clothes. So if you don’t expose your skin to sun around noon, it’s good to take a look at your 25(OH)D3 levels, even in summer.
Health of teeth and bones
It was believed for a long time that the only function of vitamin D was preventing rickets in children, and it is the skeletal system that the substance is mainly associated with. Undoubtedly, it does have an enormous impact on bones.
According to research, normal vitamin D levels reduce the frequency of bone fractures. It can be caused by its great effect on calcium and phosphorus management, as, thanks to the vitamin, they are absorbed in the intestines faster and then used more efficiently by the organism. Vitamin D also positively affects maintaining normal and stable calcium levels by, among other factors, its effect on the parathyroid glands and the reduced secretion of parathormone which releases calcium stored in bones.
Vitamin D is an important player in regulating the activity of inflammatory cytokines of the immune system. Studies prove its efficiency in reducing TNF-alpha and increasing interleukin 5. It’s worth noting that it is able to reduce the frequency of colds. Because of that, it is good to reach for vitamin D in spring and autumn, when its production decreases and you are more vulnerable to infections due to low temperatures and weather changes.
It has been observed during tests that the vitamin causes increased insulin secretion in the pancreas and increases cell sensitivity to the substance. It has been noted that with normal blood vitamin D3 levels, the frequency of diabetes also decreases.
That can be partly ascribed to the increase in adiponectin levels. It is a cytokine produced by fatty tissue that has anti-inflammatory properties and positively affects insulin sensitivity.
Effect on mortality and longevity
Tests suggest that normal vitamin D levels reduce the risk of many unpleasant diseases. They include colon, ovary and prostate cancers, and neurodegenerative diseases, such as multiple sclerosis. Clinical tests conducted on large groups of people suggest a decreased number of deaths irrespective of the cause, depending on 25(OH)D3 levels in the organism. Such properties make cholecalciferol very helpful for people who strive for maximum longevity and maintaining good life quality in their last years.
Androgen levels in men
Tests suggest that normal vitamin D levels reduce the risk of many unpleasant diseases. They
Vitamin D can improve the life quality of men who suffer from low testosterone levels. Supplementation can increase both total and free testosterone levels by reducing sex hormone binding globulin.
To sum up, HEALTHY ORIGINS Vitamin D3 is recommended for people who want to improve overall health, as well as those with a deficiency proven by lab tests. It is particularly worth attention in the case of joint and bone pains, mood disorders, and low immunity to infections.
Permanent intake of preparations with vitamin D3, at least outside the summer season, is a mandatory element of taking care of your own health. The product contains a fairly high dose of vitamin D3 and, according to health care professional, one capsule should be used daily.
Vitamin D3 is fat-soluble, so it must be taken with a meal containing fat. Vitamin D3 combined with vitamin K2. This prevents osteoporosis.
Healthy Origins® is a renowned manufacturer and distributor of dietary supplements. The company has been present on the market since 1996, specializing in health supplements. The company's mission is to strengthen the health condition thanks to proven and safe substances whose effectiveness has been confirmed by scientific research.
Healthy Origins® products are distinguished by excellent quality and popularity among consumers. All preparations are made according to the guidelines of good cGMP production practice. The manufacturer pays a lot of attention to the origin of the ingredients used in production – he cooperates exclusively with leading suppliers and leaders in the industry and chooses branded, patented components. The company does not use any fillers or additives that could reduce the bioavailability of active substances.
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Vitamin D belongs to fat soluble vitamins, occurs in three forms: calciferol (vitamin D1) ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), it is formed under the action of sunlight for at least 15 minutes per day. In the absence of sunlight it should be administered in the diet in the form of fish oil (Vitamin A + D3) and fish oils. It is responsible for the absorption of calcium and phosphorus. It is the building substance of bone tissue particularly necessary during pregnancy, childhood, and for athletes. It is a component of dietary supplements and nutrients among competetive athletes. Deficiency of vitamin D causes children growth inhibition, and rickets.
For adults - deficiency causes osteomalacia.
Excess of vitamin D causes headaches, alopecia, nausea, drowsiness, blurred vision, pain in the long bones, the deposition of calcium deposits.
Dosage: 400 IU units during the day.
Lanolin is obtained in the process of cleaning of raw sheep wool from the so-called wool fat, protecting it from getting wet and unbeneficial weather conditions.
Lanolin is commonly used for the production of ointments and creams with lubricating and softening effect, however, it also found application in the production of dietary supplements and more precisely vitamin D3.
In order to obtain vitamin D3 from lanolin, it undergoes cleaning and crystallization and then proper chemical processes, as a result of which 7-dehydrocholesterol is produced - a precursor of vitamin D3, the same which is produced in skin under the influence of UV radiation. 7-dehydrorocholesterol obtained from lanolin is then subjected to the above mentioned radiation, being transformed to vitamin D3.
Cholecalciferol, or vitamin D3, is an organic chemical that belongs to the family of D vitamins. It is naturally found in fatty fish, fish oil, egg yolks, milk and dairy products. It is also synthesized in the human body. It is formed from 7-dehydrocholesterol present in the keratinocytes of the spinous and the basal layers of the epidermis, and a pre-requisite for initiating this process is the action of 290-315 nm wavelength UVB radiation on the skin.
Cholecalciferol is a biologically inactive compound. In the body, it undergoes enzymatic hydroxylation – first in the liver, with the participation of 25-hydroxylase, when calcidiol is formed and secondly in the kidneys, where under the influence of 1-α-hydroxylase, calcidiol is converted into the final active form – calcitriol.
The most important role of vitamin D3 in the body is the regulation of calcium-phosphate metabolism, which directly affects normal skeletal mineralization. In addition, it is involved in cell proliferation and differentiation, insulin secretion, as well as in some functions of the nervous, endocrine and immune systems.
Cholecalciferol is the most popular form of vitamin D used in dietary supplements. Studies show that supplementation with vitamin D in this form most effectively and rapidly raises the level of 25 (OH) D3 – a metabolite that is a marker of the level of vitamin D in the body.
Dosage: according to RDI standards for individual age groups.
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