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Affron Affron 90 caps.
Hepatica
14.88 $
Location: eu

Affron 90 caps.

From 3 units only: 14.59 $ / Units. -2%

Shipping weight: 200g
Vegetarian
Vegan
14.88 $With VAT
0.17 $ / serving
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Description
  • High-quality standardised extract from saffron
  • Alleviates anxiety and depressive symptoms
  • Natural alternative to antidepressants
  • Supports the maintenance of emotional balance
  • Facilitates falling asleep and improves sleep quality
  • Prevents sexual disorders
  • Reduces bothersome PMS symptoms
  • Improves mental capacity
  • Promotes positive mood
  • Reduces cortisol levels
  • Increases energy levels
  • Suppresses flashes of anger
  • Reduces fatigue
  • Supports fertility
  • Reduces tension
  • Promotes relaxation
  • Stabilizes mood
  • Improves memory
  • Stimulates libido
  • Reduces appetite

Hepatica, Affron® is a dietary supplement which contains the patented extract from hand conditioned saffron stigmata, standardised for the minimum content of 3.5% of lepticrosalides. These are a complex of bioactive substances which are responsible for the antidepressant, anxiolytic and procognitive properties of saffron.

The manufacturer guarantees the highest quality of the raw material and strict control at every production stage, starting from farming, through harvesting, to the ready extract. Thanks to that, the end-product standard is much higher than other supplements which contain saffron stigmata.

The supplement was designed for people who want to improve their mental well-being, increase energy level and resistance to stress in a natural and safe way. It effectively supports treatment of mild and advanced depression and anxiety; it some cases it can even replace synthetic antidepressants. It is also useful in case of sexual disorders, especially those resulting from the use of antidepressants (e.g. from the SSRI group). Saffron extracts are popular among women who want to get rid of bothersome PMS symptoms or reduce body weight.

Saffron (Crocus sativus) is a tuber, one of the most expensive spices in the world, valued for its taste and commonly used in alternative medicine. Numerous clinical studies have proven its anti-inflammatory, immunomodulating and antioxidant properties. In herbal medicine, saffron gained its popularity as an antidepressant and support for sexual health.

Saffron stigmata are used for therapeutic purposes. Each flower produces only three stigmata which are so brittle that they have to be harvested manually (hence such high prices of saffron). Despite their small size, saffron stigmata contain about 150 different biochemical compounds; the most important are so called lepticrosalides (crocin, crocetin and its esters, picrocrocin and safranal). The highest quality supplements are standardised for the content of these substances.

Antidepressant properties
Saffron components have great potential in depression treatment. They affect the monoamines which are crucial for the well-being. It has been proven that crocin and safranal block the reuptake of serotonin, dopamine and norepinephrine. This results in good mood, motivation, energy and vitality.

Antidepressant mechanism of saffron action includes also the influence on the glutamatergic system. Crocetin shows affinity to NMDA receptor, and particularly to the site binding phencyclidine which is responsible for blocking the ionic channel of NMDA receptor. One of the hypotheses about depression pathophysiology says that compounds inhibiting glutamatergic transmission shows antidepressant properties. While using strong antagonists of NMDA receptor is subjects to the risk of side effects, the substances showing mild affinity to the NMDA receptor seem to be promising remedies to mild and medium depression.

Saffron extracts not only improve mood but also soothe the nerves and have anti-anxiety properties. The most important role is played by safranal which affects GABA-alpha receptor and modifies the benzodiazepine site of this receptor.

In clinical trials, researchers compared effectiveness of saffron extracts to effects obtained by using classic antidepressants, imipramine and fluoxetine. It was unambiguously demonstrated that the effects are equivalent, while saffron extracts are much better tolerated and do not cause side effects.

Procognitive action
Advantages of saffron extracts include memory and cognitive functions improvement. In some countries, saffron is commonly used in the treatment of cognitive disorders associated with age or resulting from neurodegenerative diseases (e.g. Alzheimer’s disease). It is also effective in the prevention of such disorders.

Crocin isolated from saffron prevents aggregation of beta-amyloid, a protein which plays an important role in the pathogenesis of neurodegenerative diseases. In turn, safranal slightly reduces the activity of acetylcholinesterase. Thanks to that, the amounts of acetylcholine in the body system rise, which results in faster learning, increased ability to associate facts and better memory.

Improved sexual performance
In the traditional folk medicine, saffron is considered to be an aphrodisiac and spice improving fertility. It is surprisingly effective in people in whom sexual disorders are side effects of antidepressant drugs from the SSRI group. It does not change effectiveness of therapy and reduces the majority of dysfunctions, such as erection disorders and premature ejaculation in men and vaginal dryness in women. Moreover, in both sexes saffron restores interest in sex, positively affects excitement and improves satisfaction with sex.

Studies prove positive influence of saffron on male fertility. In men with low sperm parameters, saffron seeds extracts improve semen quality and sperm motility.

Relieving symptoms of PMS
Large-scale research proved that saffron extracts effectively relieve bothersome symptoms of premenstrual syndrome (PMS), both mental (tearfulness, irritation, mood swings) and physical (swelling, breast tenderness, lower back pain, migraines). 76% of women using saffron confirmed that ailments disappeared (in the placebo group only 8%).

Body weight reduction
Saffron can be effectively used by people who want to reduce their body weight. It will be also useful if additional kilograms result from snacking. Positive influence of saffron on the nervous system, raising serotonin level and reduced anxiety facilitate appetite regulation and hunger reduction. It reduces also craving for snacks which often results from the need to improve mood, not from the real hunger.

In the one of the pilot studies, the group of 31 obese women used saffron extracts for 8 weeks, while 29 women of a similar age and body weight took placebo. During the research, they did not change their lifestyle nor diet. After 9-week therapy, the group using saffron observed significant body weight loss when compared to the placebo group. Also, the frequency of snacking dropped. Women claimed that they could easily manage the appetite and do feel craving for snacks.

To sum it all up, Affron® is an interesting proposition for people who struggle with low mood, anxiety or depression. It is also an optimal choice for those who decided on the traditional antidepressant therapy but they suffer from deterioration of sexual life quality, which is the most common side effects of antidepressants. An additional advantage of the preparation use is the improvement in memory and mental performance. It can also reduce additional kilograms. 

Directions for use
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Composition

Container size: 90 capsulesServing size: 1 capsuleServings per container: 90
per 1 capsuleamount%DV
Standardized Saffron Extract (Crocus sativus L.) 30 mg*

Other ingrednients

Microcrystalline cellulose, hydroxypropyl methylcellulose.

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