Since 2005
You are currently:
Choose language:
Need help?
Leave message
Choose language:
Select currency: $ £
Since 2005
en
USD
0 0.00 $
Since 2005  sales@mz-store.co.uk  7767803657
Hydroxo B12 + Folinic Acid Hydroxo B12 + Folinic Acid

Seeking Health Hydroxo B12 with Folinic Acid is a supplement with two compounds which act synergistically in regulating methylation: vitamin B12 in the form of hydroxocobalamin and folinic acid. They support energy metabolism of every person with increased physical load and support also efficient functioning of the cardiovascular system.

Vitamin B12 – contained in the supplement as hydroxocobalamin. It ensures much higher absorption than the popular form cyanocobalamin. Studies indicate that hydroxocobalamin is the most bioavailable non-methylated form of vitamin B12. In the body, it functions as an active enzyme in numerous reactions affecting energy mechanisms.

Folic acid – also belongs to B vitamins, found under the number 9. It is vital to proper gene expression, regulates the development of neural tube in the foetus and neurons in adults. It is shown to affect significantly the mood and activity of neurotransmitters. More and more often high doses of folic acid are suggested as an alternative for strong psychiatric medications.

Folic acid vs. folinic acid
Although both names sound similar, and metabolically speaking, both acids are on the same pathway, there is a significant difference between them when it comes to supplementation.

Folinic acid, which is a common name for 5-formyltetrahydrofolate, is one of the two metabolically active forms of folic acid. For many years, folic acid was supplemented with the thought that it will easily enter the pathway of its transformations and convert to its bioactive derivatives. Meanwhile, more and more research suggests that the tendency for folic acid metabolism disorders is increasing. It is estimated that over half of society may have problems with synthesising the enzymes necessary for dealing with the crucial compound.

That is why it is much more beneficial to supplement the metabolically active forms of folic acid, that is folinic acid and 5-methyltetrahydrofolate. What is more, recent research demonstrates that supplementation of ordinary folic acid can be harmful for the organism, accelerate the development of cancer, and have a negative effect on foetal development.

Complex methylation support
Even though both vitamin B12 and folinic acid demonstrate many autonomous properties in the body, they have been used and selected in ratio maximising their synergistic action on improving methylation. It is a process comprising a range of reactions determining bioavaility of nutrients. Its disorders lead to impairment of all metabolic functions of the body, especially affecting energy mechanisms.

The role of vitamin B12 and folinic acid in homocysteine methylation
Cobalamin is a coenzyme of two reactions in the methylation pathway: the conversion of homocysteine into methionine and methylmalonyl-CoA intosuccinyl-CoA. The main task of the supplement is to improve the first one of these reactions. The formula provides the body with hydroxocobalamin, easily converted into the methylated vitamin B12 which is an active enzyme stimulating the production of  H4-folate from 5-methyl-H4-folate. 5-methyl-H4-folate (otherwise known as levomefolic acid) is a biologically active form of folic acid. Consequently, the formula supports comprehensively this phase of methylation.

The impact of methylation on metabolic homeostasis
The conversion of homocysteine has a significant role in cellular metabolism. Its disorders lead to impairment of the whole methylation process which entails disorders in other regulatory mechanisms of the body. It affects especially body energy balance because methylation products are intermediate substrates in the Krebs cycle – the basic energy mechanism of the human body.

Hyperhomocysteinaemia and the health of the cardiovascular system.
Disorders of homocysteine methylation will also cause its elevated concentration in the blood where it degenerates the blood vessel bed. Hyperhomocysteinaemia is associated with damages to endothelium of blood vessels. Because of that, it is identified as the primary cause of developing an atherosclerotic plaque.

To sum up, Hydroxo B12 with Folinic Acid is a complex support for the basic reaction in the methylation process. It ensures efficient functioning of body energy balance and healthy cardiovascular system. The supplementation with this formula should be considered by hard-training athletes as well as office workers – studies demostrate that mental stressors show the same ability to impair methylation as physical effort.

Out Of Stock
Since 2005
Notify me of availability
Hydroxo B12 + Folinic Acid Hydroxo B12 + Folinic Acid 60 lozenges
Seeking Health
21.34 $

Hydroxo B12 + Folinic Acid 60 lozenges

features

Fat loss:
Concentration:
Health:
Regeneration:

- Delivery even day after tomorrow

- Foreign shippment from 5.57 $ Every 81.03 $ reduces shipping costs by 2.70 $

You have got questions about the product

sales@mz-store.co.uk

01709231594 (mon.-fri 900-1700)

21.34 $
Notify me of availability
Growing interest of this product

- Delivery even day after tomorrow

- Foreign shippment from 5.57 $ Every 81.03 $ reduces shipping costs by 2.70 $

You have got questions about the product

sales@mz-store.co.uk

01709231594 (mon.-fri 900-1700)

Description
  • Complex of the most bioavailable vitamin B12 and folinic acid
  • Syngergistic effects for complex methylation support
  • Promotes metabolism at the cellular level
  • Provides enzymes for many reactions in the body
  • Prevents atherosclerotic plaque formation
  • Improves body energy mechanisms

Seeking Health Hydroxo B12 with Folinic Acid is a supplement with two compounds which act synergistically in regulating methylation: vitamin B12 in the form of hydroxocobalamin and folinic acid. They support energy metabolism of every person with increased physical load and support also efficient functioning of the cardiovascular system.

Vitamin B12 – contained in the supplement as hydroxocobalamin. It ensures much higher absorption than the popular form cyanocobalamin. Studies indicate that hydroxocobalamin is the most bioavailable non-methylated form of vitamin B12. In the body, it functions as an active enzyme in numerous reactions affecting energy mechanisms.

Folic acid – also belongs to B vitamins, found under the number 9. It is vital to proper gene expression, regulates the development of neural tube in the foetus and neurons in adults. It is shown to affect significantly the mood and activity of neurotransmitters. More and more often high doses of folic acid are suggested as an alternative for strong psychiatric medications.

Folic acid vs. folinic acid
Although both names sound similar, and metabolically speaking, both acids are on the same pathway, there is a significant difference between them when it comes to supplementation.

Folinic acid, which is a common name for 5-formyltetrahydrofolate, is one of the two metabolically active forms of folic acid. For many years, folic acid was supplemented with the thought that it will easily enter the pathway of its transformations and convert to its bioactive derivatives. Meanwhile, more and more research suggests that the tendency for folic acid metabolism disorders is increasing. It is estimated that over half of society may have problems with synthesising the enzymes necessary for dealing with the crucial compound.

That is why it is much more beneficial to supplement the metabolically active forms of folic acid, that is folinic acid and 5-methyltetrahydrofolate. What is more, recent research demonstrates that supplementation of ordinary folic acid can be harmful for the organism, accelerate the development of cancer, and have a negative effect on foetal development.

Complex methylation support
Even though both vitamin B12 and folinic acid demonstrate many autonomous properties in the body, they have been used and selected in ratio maximising their synergistic action on improving methylation. It is a process comprising a range of reactions determining bioavaility of nutrients. Its disorders lead to impairment of all metabolic functions of the body, especially affecting energy mechanisms.

The role of vitamin B12 and folinic acid in homocysteine methylation
Cobalamin is a coenzyme of two reactions in the methylation pathway: the conversion of homocysteine into methionine and methylmalonyl-CoA intosuccinyl-CoA. The main task of the supplement is to improve the first one of these reactions. The formula provides the body with hydroxocobalamin, easily converted into the methylated vitamin B12 which is an active enzyme stimulating the production of  H4-folate from 5-methyl-H4-folate. 5-methyl-H4-folate (otherwise known as levomefolic acid) is a biologically active form of folic acid. Consequently, the formula supports comprehensively this phase of methylation.

The impact of methylation on metabolic homeostasis
The conversion of homocysteine has a significant role in cellular metabolism. Its disorders lead to impairment of the whole methylation process which entails disorders in other regulatory mechanisms of the body. It affects especially body energy balance because methylation products are intermediate substrates in the Krebs cycle – the basic energy mechanism of the human body.

Hyperhomocysteinaemia and the health of the cardiovascular system.
Disorders of homocysteine methylation will also cause its elevated concentration in the blood where it degenerates the blood vessel bed. Hyperhomocysteinaemia is associated with damages to endothelium of blood vessels. Because of that, it is identified as the primary cause of developing an atherosclerotic plaque.

To sum up, Hydroxo B12 with Folinic Acid is a complex support for the basic reaction in the methylation process. It ensures efficient functioning of body energy balance and healthy cardiovascular system. The supplementation with this formula should be considered by hard-training athletes as well as office workers – studies demostrate that mental stressors show the same ability to impair methylation as physical effort.

Directions for use
Manufacturer
Reviews (0)

Composition

Composition

Container size: 60 vegetarian lozengesServing size: 1 vegetarian lozengeServings per container: 60
per 1 lozengeamount%DV
Folinic Acid800 µg200%
Vitamin B12 (as Hydroxycobalamin)1000 µg41,667%

Other ingrednients

Xylitol, ascorbyl palmitate, silica, and natural cherry flavor.

Similar products
Best to combine with
Swanson
25.66 $

High dose of gamma and delta-tocotrienols with a strong antioxidant potential. 50 times stronger action.

Buy
Now Foods
12.96 $

Well-absorbed source of zinc, a cofactor of many key enzymes, it may also increase testosterone levels.

Buy
Himalaya
7.83 $

Unique combination of three Ayurvedic herb. Cleanses and tones the digestive system.

Buy
Doctor's Best
24.04 $

Probiotic supplement that helps support a positive balance of microflora in the intestines.

Buy
Now Foods
17.56 $

Stimulates metabolism; increases thermogenesis; stabilises blood sugar levels.

Buy
Doctor's Best
15.94 $

Complete formula that guarantees the efficacy of digestion. Stimulates digestion and prevents indigestion.

Buy

Folinic acid

Information

Folinic acid - 5-formyltetrahydrofolate, a biologically active form of folic acid. Its supplementation is recommended especially to people with methylation dysfunctions, as it is essential for the transformation of folic acid to the active folate. Taking into consideration the increasing tendency to disorders in this respect, folates are more and more often recommended as the basic, preferred forms of supplementation with folic acid.

Supplementation with these folates is especially recommended to women who are planning pregnancy or are pregnant. Folic acid in the biologically active form is responsible for regulating the formation of neural tube in the fetus and is conducive to its proper development.

In adults, folates are conducive to optimal methylation processes. It takes part in transforming homocysteine to methionine, thanks to which it demonstrates positive influence on the health of the cardiovascular system. In this way, it positively influences psyche, as the effectiveness of this process is conducive to the production of S-adenosyl methionine with considerable influence on maintaining proper emotional states.

Some sources also indicate the protective influence of folates on the development of cancers. This information, however, is not fully unambiguous. The present state of knowledge suggests that since the optimal supply of folates really decreases the risk of cancer development, its supplementation in excessively high doses may demonstrate the reverse effect.

 

Latest on blog

The most common training mistakes made by beginners.

The most common training mistakes made by beginners.

Are you looking for advice on how to do exercises? Or maybe you’ve been practicing for some time and do not you see any progress? Perhaps you are making the...

Read more
Macrobiotic diet

Macrobiotic diet

Macrobiotic diet is a way of nutrition that originates from Chinese philosophy. It adheres to the principle of two Jin and Yang forces that are in balance with...

Read more
Bulletproof coffee – make sure that you do it well!

Bulletproof coffee – make sure that you do it well!

Bulletproof coffee is a morning drink that thanks to the content of the respective components can provide us with a number of positives including morning energy,...

Read more
Gym equipment – Roman bench

Gym equipment – Roman bench

Equipment for gym training can sometimes make you dizzy. As a rule, you know how to practice on it, although there may always be questions. A good example is the...

Read more
Lecithin helps in building muscles!

Lecithin helps in building muscles!

In general about lecithin and its actionsCharacteristics of associate compoundsHelp for the brainLecithin and muscle mass – a diagram of the properties of...

Read more
“Don’t starve”… or maybe you should?

“Don’t starve”… or maybe you should?

The interest in training at the gym, which significantly affect, for example, the improvement and aesthetics of the figure, should be associated with increasing...

Read more

Sign up for our newsletter
And receive coupons, news, special offers and much more!

Customer service

Complaints

001 844 530 3647

MZCatalog - recommended dietitians

MZCatalog - recommended trainers

MZCatalog - recommended clubs

Black Supps Ltd (11986057)
235-239 High Road London N22 8HF
shop@mz-store.com +44 7767803657