Swanson Berberine Complex 90 caps.

• 150 mg of pure berberine HCl contained in 1 capsule
• Enriched with Ceylon cinnamon, fenugreek and gurmar
• A natural supplement for the treatment of diseases of civilization
• Helps maintain proper blood sugar levels
• Supports the reduction of spare fat
• Promotes improved insulin sensitivity
• Optimizes blood lipid profile

Swanson Berberine Complex is a natural dietary supplement based on berberine (Berberine HCl), enriched with the synergistic effects of Ceylon cinnamon, fenugreek and gurmar. The formula promotes improvement of glycemia and insulin sensitivity, and supports normalization of blood lipids.

Berberine is a natural plant alkaloid found in many plants, whose beneficial effects were noted thousands of years ago in Traditional Chinese Medicine. Nowadays, the importance of berberine in medicine is emphasized, especially in the area of civilization diseases (improves glycemia, prevents cancer, lowers blood pressure, supports weight loss, optimizes blood lipid profile). The preparation contains pure berberine derived from the root of Berberis aristata.

The special interest in berberine is primarily due to its anti-diabetic potential. This is because berberine has an effect on lowering blood glucose levels, so it may have a potentially beneficial effect on diabetes and obesity. What's more - berberine's hypoglycemic effects are similar to those that can be achieved by taking metformin.

Berberine helps restore blood sugar balance through a number of mechanisms, including increased expression of insulin receptors, increased glucose uptake, delayed breakdown of carbohydrates into simple sugars, and regulation of glucagon secretion. In addition, it exerts a protective effect against the pancreas.

Berberine promotes a reduction in glycated hemoglobin (HbA1c). The amount of glycated hemoglobin reflects blood glucose levels over the past three months and is used in diagnostics to monitor long-term glycemic control among patients with diabetes. Based on HbA1c levels, it is possible to assess the risk of developing cardiovascular complications. There is a strong correlation between the possibility of clinical complications and the HbA1c level.

In addition, berberine has the effect of lowering the levels of the LDL fraction of cholesterol and triglycerides and increasing the HDL-C fraction. It contributes to improved lipidogram and aids in the reduction of spare fat. It has also been shown to positively affect liver function in nonalcoholic steatohepatitis (NASH).

Berberine also affects the activation of AMPK kinase, leading to inhibition of the NF-κB factor, which is involved in the cell's response to stress (this also leads to improved insulin resistance). Thus, it plays an important role in reducing the secretion of pro-inflammatory cytokines, and thus has an anti-inflammatory effect.

In addition, berberine has also been proven to have a number of other properties, including antimicrobial and antiviral activity, support of cognitive function, prevention of Alzheimer's disease, and beneficial effects on mitochondrial function.

Ceylon cinnamon (Cinnamomum Verum) or true cinnamon is one of the most popular and longest-used spices. In addition to its culinary value, it has many valuable health-promoting properties.

Research results suggest that cinnamon or compounds isolated from it may have beneficial effects on the course of diabetes, cancer and cardiovascular diseases. Cinnamon has been shown to normalize blood glucose levels and help reduce the risk of type II diabetes complications, namely. macroangiopathy, nephropathy and retinopathy (similar to berberine, by lowering glycated hemoglobin levels). However, the antidiabetic mechanism of action of cinnamon may also be due to many other mechanisms.

Fenugreek (Trigonella forenum-graecum), according to Traditional Chinese and Hindu Medicine, is used particularly in diabetes to lower blood glucose levels. Its hypoglycemic effect has been described since ancient times.

The sources of fenugreek's hypoglycemic activity are believed to be in a number of areas. One is the presence in its seeds of the amino acid 4-hydroxyisoleucine, which is attributed to its effect on stimulating insulin release from Langerhans island cells. The hypoglycemic role is also attributed to the synergistic action of the chemical compounds present in the plant.

In addition, fenugreek has hypolipidemic, anti-inflammatory, antimicrobial effects, as well as beneficial effects on the nervous system, which can prove extremely valuable, especially in the case of neurodegenerative disorders.

Gurmar (Gymnema sylvestris) is a tropical plant whose leaves have been used by Ayurvedic medicine specialists for 2,000 years. According to the Hindus, chewing its leaves contributed to the deterioration of the ability to experience sweet taste, which had the effect of reducing the appetite for sweet foods (it was therefore described as a "sugar destroyer").

Gurmar is a source of many bioactive substances, the most noteworthy of which include hydroxycitric acid - HCA (partially reduces sugar absorption from foods) and chromium, which is part of GTF (Glucose Tolerant Factor) - a glucose tolerance factor and one of the most important regulators of the sense of hunger and satiety.

Gurmar sensitizes pancreatic cells to insulin, normalizes blood glucose levels, improves liver and pancreatic function, reduces cravings for sweets and optimizes the lipid profile.

In summary, Swanson Berberine Complex is a dietary supplement that naturally supports the treatment of lifestyle diseases, especially type 2 diabetes, obesity and hypertension. The diverse set of chemical compounds contained in the individual plants makes the formula have a wide spectrum of biological activity.