ZMA is a combination of zinc, magnesium and vitamin B6. This combination provides an increase of testosterone, IGF-1 and leptin, so this supplement enhances the anabolic signal. It effectively reduces the activity of cortisol - a strongly catabolic hormone. It is also a means of overcoming the pain and muscle cramps. When used regularly in the evenings it introduces a deep, full, restful sleep, thus allowing the body to complete the regeneration of cells, tissues, organs and systems.