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Methylation processes are constantly occurring at many levels of the human body and are involved in a huge number of biochemical transformations that influence health. They determine the formation of compounds such as creatine, carnitine, coenzyme Q10, melatonin, choline, glutathione (a powerful antioxidant) or neurotransmitters responsible for the proper functioning of the brain. Methylation processes are also crucial for the proper course of the Krebs cycle, in which energy is generated in the form of ATP, as well as for amino acid metabolism and detoxification reactions in the liver. In addition, methylation is responsible for regulating the expression of some defective genes and thus protects the body against, e.g., the development of cancer.

A side product of the methylation reaction is homocysteine ​​– a sulfuric amino acid that is formed from methionine. It is an important compound for the functioning of the nervous system and is a donor of methyl groups. However, too high concentration of homocysteine adversely affects the body, induces inflammation and contributes to the formation of many diseases, especially those related to the cardiovascular system. Methylation disorders may lead to a decrease in homocysteine ​​neutralization efficiency, which may quickly lead to hyperhomocysteinemia and the afore-mentioned diseases. Besides, methylation disorders may result in the formation of cancer cells, increase oxidative stress; they also disrupt the metabolism of amino acids and slow down energy production.

Methylation disorders are very often caused by deficiencies of vitamins and compounds found naturally in the body. These include, e.g., vitamin B12, B6, folic acid, choline or S-adenosylmethionine. In order to increase the efficiency of methylation processes, it is worth to replenish these deficiencies. This is to be achieved by using proven dietary supplements that are available in our store. In addition, we offer special multicomponent formulas that support methylation and regulate homocysteine levels.

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Suppcount
6.15 $

Vitamin B12 in a biologically active, methylated form.

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Apollo's Hegemony
18.42 $

An advanced complex of B vitamins in biologically active forms.

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Apollo's Hegemony
9.20 $

Active, methylated 3rd-generation folate.

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Apollo's Hegemony
6.89 $

Vitamin B12 in its active, methylated form.

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Apollo's Hegemony
11.50 $

A combination of active, methylated vitamin B12 and calcium methylfolate.

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Suppcount
9.68 $

Metabolically active forms of B vitamins. Support optimal homocysteine metabolism.

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Suppcount
6.08 $

Active, methylated folate of the third generation. Recommended for people with impaired folic acid metabolism.

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BeOrganic
10.37 $

A high dose of natural, easily absorbed folates in the form of organic spinach leaf extract.

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Methyl B12 + 5-MTHF Available soon
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Methylated form of vitamin B12 and folate. A formula recommended for people with MTHFR gene mutation.

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Seeking Health
19.59 $

Dietary supplement with high doses of active forms of vitamin B12 and B9.

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Aliness
8.04 $
(7)

A preparation containing the patented, active fourth generation folate, Quatrefolic®.

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TMG Crystals Out of stock
Jarrow Formulas
8.99 $

TMG Crystals™ provides trimethylglycine, an important methyl donor.

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TMG 500mg Out of stock
Life Extension
11.29 $

The supplement maintains healthy level of homocysteine and supports detoxification of the organism.

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Active B12 Out of stock
Seeking Health
22.82 $

Formula containing active forms of vitamin B12, high dose in one capsule. Appropriate for vegetarians.

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Optimized Folate Out of stock
Life Extension
15.90 $

5-MTHF is up to seven times more bioavailable than ordinary folic acid.

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L-5-MTHF 1000mcg Out of stock
Seeking Health
17.29 $

It supports effective methylation processes in the organism.

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TMG Powder Out of stock
Apollo's Hegemony
12.68 $
(5)

Pure trimethylglycine (TMG) powder. Support for methylation processes and psychophysical condition.

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Active B12 Out of stock
Seeking Health
11.29 $

Formula containing active forms of vitamin B12, high dose in one capsule. Appropriate for vegetarians.

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HomocysteX Plus Out of stock
Seeking Health
25.12 $

Product regulating homocysteine level in blood. Formula enriched in TMG additive.

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Seeking Health
29.74 $

A complex of vitamins and minerals. It contains active methyl forms of B12 and folate.

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Aliness
8.04 $

Diet supplement covering 11 key group B vitamins. It has a beneficial influence on the condition of the skin.

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Optimized Folate Out of stock
Life Extension
13.60 $

5-MTHF is up to seven times more bioavailable than ordinary folic acid.

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Aliness
10.35 $

Vitamin B-complex enclosed in vegetarian capsules. The product contains high doses of active substances.

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Aliness
13.81 $

A complex of B vitamins suitable for vegetarians. The product contains a methylated form of B12 vitamin.

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Aliness
5.74 $

Vitamin B6 in the active coenzyme form - P-5-P.

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18.44 $
(2)

Comprehensive guide to the world of methylation.

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Fully Active Folate Out of stock
Doctor's Best
12.22 $

The mostly bioactive form of folic acid in form of glucosamine salt of 5-MTHF acid.

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Methylcobalamin Out of stock
Life Extension
25.12 $

Methylcobalamin is the form of vitamin B12 active in the central nervous system.

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Liposomal Methyl B-12 Long-term out of stock
Quicksilver
45.87 $

Vitamin B12 in the active methylated form. Supports proper functions of the nervous system.

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TMG Powder Out of stock
Life Extension
12.22 $

Dietary supplement lowering the level of homocysteine in the organism.

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TMG
TMG Out of stock
Now Foods
18.21 $

Betaine improves the amplification of DNA by reducing the formation of secondary structure in GC-rich regions.

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Seeking Health
33.42 $

A complex of active folate, vitamin B12, and other ingredients. Gently supports body's methylation processes.

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DMG 100mg Out of stock
Source Naturals
from 8.53 $

Dimethylglycine source. It promotes energy processes that support mental and physical performance.

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Folate 800mcg Out of stock
Swanson
5.53 $

Encapsulated folate of the 4th generation – Quatrefolic®. Reduces the risk of hyperhomocysteinemia.

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Swanson
3.46 $

Patented form of Quatrefolic® folic acid. It promotes the proper functions of the nervous system.

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Methyl-Guard Plus Out of stock
Thorne Research
64.31 $
(1)

Methyl-Guard Plus supports methylation cycle pathway.

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Aliness
16.11 $

Blend of homocysteine modulators. Supports normal methylation processes.

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