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Active B12 with L-5-MTHF by Seeking Health is a dietary supplement in the form of lozenges which contains active forms of vitamin B9 (levomefolic acid) and B12 (methylcobalamin and adenosylcobalamin). Active substances in these forms ensure efficient absorption and high bioactivity of both vitamins. Both ingredients have a positive effect on normal function of the whole body and protect its tissues from a harmful impact of external factors.
Active forms of vitamin B12 – this vitamin, otherwise known as cobalamin, is found in the supplement in the form of two bioactive ingredients: methylcobalamin and adenosylcobalamin. They do not need to be activated after absorption and that is why the administered dose shows its full biological effect.
Methylcobalamin is a form of vitamin B12 which contains a methyl group. Its presence influences positively the process called methylation. The main goal of methylation is to activate and deactivate many enzymes which regulates the function of the whole body. Harmful factors which we encounter on a daily basis decreases the efficiency of this process. This contributes to declining health and the lack of energy. In addition, it happens more often that the MTHFR gene, which is directly responsible for methylation in the body, is mutated. Because of that, adequate vitamin B12 supplementation is very important.
The second form of vitamin B12 in this supplement is adenosylcobalamin. It is also an active form which has a positive effect on many processes directly after absorption. It is a cofactor necessary for normal function of methylmalonyl-CoA that is responsible for mitochondrial energy production.
Cobalamin has also a beneficial effect on the immune system. It activates the enzyme methionine synthase which converts homocysteine into methionine. It is a very significant process because high homocysteine levels have a negative impact on the function and structure of blood vessels. They cause many diseases which include thrombosis and atherosclerosis. Owing to that, vitamin B12 prevents blood vessel degeneration which contributes to normal cardiovascular function.
In addition, it stimulates the production of red blood cells. This helps combat effectively anaemia and improves gas exchange in the body. Adequate oxygen supply to cells contributes to efficient mitochondrial energy production.
Vitamin B12 has also been shown to influence positively the nervous system. It protects nerve cells, neurons, from overactivation of glutamate receptors. Binding large amounts of glutamate to them causes excitation that damages severely neurons. What is more, a reduction in homocysteine levels helps maintain a good condition of blood vessels which provide the brain with oxygen. The removal of metabolic waste products is also improved which contributes to efficient function of the central nervous system. The overall nourishing and neuroprotective effect of vitamin B12 on the nervous system promotes memory formation, improves cognitive functions and fosters general well-being.
The methionine synthase activated by cobalamin converts homocysteine into methionine, which has a positive impact on metabolism of cells. It protects them from mutation and promotes normal synthesis of proteins, lipids and DNA.
Levomefolic acid (5-MTHF) – is a bioactive form of vitamin B9. Many studies show that it acts in synergy with other vitamins from this group, in particular with vitamin B12. An important feature of levomefolic acid is that it crosses easily the blood-brain barrier. Owing to that, it demonstrates a significant impact on the functioning of the nervous system which controls the function of the whole body.
Vitamin B9 regulates levels of such neurotransmitters as dopamine, noradrenaline and serotonin. This has a significant impact on thought processes and ensures well-being. The brain’s chemical balance inhibits also neurodegenerative processes.
Proper vitamin B9 levels helps protect the neurolemma from harmful factors. Its function is to ensure normal transmission of nerve impulse within a neuron. This contributes to inhibiting neurodegenerative processes and slows down the development of many diseases connected with these processes.
In addition, levels of melatonin, the hormone responsible for normal sleep and body regeneration, are normalised.
Like cobalamin, vitamin B9 contributes to reducing homocysteine levels which results in improved function of blood vessels. What is more, it stimulates the proliferation and differentiation of red blood cells in erythropoiesis which helps combat effectively anaemia.
Active B12 with L-5-MTHF is a dietary supplement which contains high doses of active forms of vitamin B12 and B9. Maintaining normal levels of these vitamins is a crucial factor which regulates properly the function of the whole body. The formula is designed for individuals who are exposed to strong mental stress and all individuals who struggle with an impaired methylation process. An additional target group are individuals with high homocysteine levels. This results from the fact that active substances in the supplement stimulate effectively the body into normalising levels of this amino acid. The formula in the form of lozenges is a convenient way to divide easily doses of the supplement.
B vitamins are water-soluble and that is why they should be swallowed with plenty of water. Consuming fat meals just before taking the supplement may cause decreased absorption of active substances.
Maintaining adequate levels of both vitamins in the body is especially important for pregnant women. However, the supplement’s dosage should be consulted with your doctor.
Seeking Health is a brand which makes sure that the products it produces are characterized by high quality and purity, therefore the majority of their products is free from magnesium stearate, allergens and GMO.
This brand is directed at fighting the causes and not the symptoms, therefore the aim of the company is primarily to help in ensuring optimal work of the digestive system, among others by launching on the market high-class products supporting digestion and regenerating and nourishing the intestines, which consequently improves bioavailability of the substances beneficial to health and increases organism’s resistance to the effect of toxins coming from external environment.
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|per portion (1 lozenge)||amount||%DV|
|Folate (as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt)||800 mcg||340%|
|Vitamin B12 (as methylcobalamin and adenosylcobalamin)||1000 mcg||41667%|
Xylitol, ascorbyl palmitate, natural cherry flavor, and silica.
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