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Apollo’s Hegemony Acetyl-L-carnitine is a dietary supplement which contains 550 mg of acetylated L-carnitine form. The modified form of the amino acid increases its potential of nootropic, neuroprotective and antioxidant properties.
Acetyl L-carnitine (ALC, ALCAR) is an acetylated and metabolically active form of an amino acid, L-carnitine, a vitamin-like substance. Its main properties include nootropic, neuroprotective and antioxidant effects as well as promotion of fat metabolism in mitochondria. Moreover, acetyl L-carnitine positively affects the condition of the cardiovascular system and tissue sensitivity to insulin; it reduces also fatigue. The substance is involved in regulation of hormonal balance; it mainly affects testosterone and cortisol levels.
Supplementation with ALCAR is recommended especially for physically and intelectually active people and for people exposed to intensive use of the nervous system and stress. Acetyl L-carnitine will be also effective as prevention and treatment support in case of male infertility and as a part of depression treatment. It is also a perfect support for adipose tissue reduction.
Nootropic and neuroprotective properties of ALCAR result from the presence of an ethyl molecule in its structure. Thanks to that, it can easily cross the blood-brain barrier, which provides effective action in the whole nervous system. By improving metabolic processes in the brain, it positively affects its efficiency.
Acetyl L-carnitine reaches the brain and provides acetyl groups which are necessary for the production of acetylcholine, one of the main neurotransmitters in the body system, responsible for memory and effective learning. This positively affects cognitive functions and improves the functioning of the entire nervous system.
Acetyl-L-carnitine, thanks to its antioxidant properties, has also strong neuroprotective effects. It stimulates also the activity of superoxide dismutase (an antioxidant enzyme) which reduces damage to DNA and cell membrane caused by free radicals, reactive oxygen species and transient metals. This results in general improvement of the so called antioxidant barrier. Acetyl L-carnitine is believed to be able to inhibit Alzheimer’s disease and reduce depression and anxiety.
By stimulating secretion of norepinephrine and serotonin, acetyl L-carnitine positively affects well-being and inner calm. It contributes also to the reduction in chronic fatigue.
Antioxidant properties of acetyl L-carnitine, apart from the protection of the nervous system, support also the mitochondria and delay ageing process.
Mitochondria belong to the group of cell organelles which are mostly exposed and sensitive to the effects of free radicals. They are microscopic energy centres located in each cell, which produce energy for the whole body system. Any damage or disorders of their functions negatively affect the functioning of the whole body.
Limiting oxidative factors positively affects functioning, condition and number of mitochondria in cells; ALCAR reduces the excess of fatty acids in cells and improves detoxification. Thanks to that, it delays ageing and reduces the risk of neurodegenerative diseases.
Regulation of the hormonal system in case of ALCAR consists in stabilisation of testosterone level in blood and reduction in cortisol level (a stress hormone). Acetyl L-carnitine affects the male sex hormone, due to stimulation of LH (luteinizing hormone) secretion, which gives the impulse for testosterone production. If it is too low, the natural production of this hormone drops, which brings negative consequences for the male health. Stimulating LH secretion affects also the amount and motility of sperm, which results in better semen quality and improves reproductive capacity.
Studies demonstrate that acetyl L-carnitine positively affects number of androgenic receptors (AR) and their sensitivity to testosterone. This means that there are more places in the body system to which the hormone circulating in the bloodstream can attach and activate its effect in the particular cells (e.g. muscle cells). Together with increased level of testosterone, these all result in better anabolic effects.
Reduction in cortisol level (a stress hormone) is possible due to the inhibition of communication on the hypothalamus-hypophysis-adrenals axis. This leads to stress reduction, improved insulin sensitivity of tissues, limited lipogenesis and catabolic processes, which directly results in better well-being, general appearance and composition of the shape. This is also beneficial for the immune system, as too high cortisol level in blood lead to the breakdown of lymphocytes.
Support for adipose tissue combustion Acetyl L-carnitine is a transporter of free short- and medium-chain fatty acids from cytoplasm to mitochondria, which enhances energy processes and provides effective fuel. It is possible due to the ability to regulate the relationship between acetyl coenzyme A to coenzyme A in the tricarboxylic acid cycle. This enhances the loss of additional kilograms and body weight control.
Moreover ALCAR increases insulin sensitivity of tissues, so that more macroelements can be transported to cells, where they can be used for energy purposes. This reduces the risk of accumulation of unused food in form of adipose tissue.
Cardioprotective properties attributable to acetyl L-carnitine reduce damages to erythrocytes and vascular cell membranes caused by free radicals. Moreover, ALCAR stimulates erythropoiesis, which is formation of red blood cells.
By improving fatty acids metabolism in mitochondria and reducing LDL cholesterol level, acetyl L-carnitine reduces the risk of fat deposits accumulating in arteries, so that it positively affects heart functions and reduces the probability of such diseases as atherosclerosis, coronary disease or infarction. It improves also the functioning of the left ventricle, so that it increases the efficiency of the organ.
Promotion of anabolic processes is possible due to optimisation of endogenous testosterone production combined with positive influence on the sensitivity and number of androgenic receptors in the body system. Moreover, inhibition of cortisol, which promotes muscular catabolism, contributes to reduction in adverse processes in the organism.
Acetyl L-carnitine has also positive influence on anabolism, due to its ability to improve insulin sensitivity and stimulate activity of the insulin-like growth factors 1 and 2 (IGF-1 and IGF-2). This all provides friendly environment for anabolic processes, mainly muscular hypertrophy.
To sum it all up, Acetyl-L-Carnitine is a must in supplementation of every physically active person. It will be also useful in case of people exposed to stress and intellectual effort. By improving transport of free fatty acids to mitochondria, acetyl L-carnitine is a valuable support in the process of adipose tissue reduction. Positive influence on anabolic processes makes it perfect support during muscle mass building. These all, together with its nootropic, neuro- and cardioprotective properties, make ALCAR a supplement of a wide health-promoting potential.
Acetyl L-carnitine is a safe measure, known mainly for its ability to support adipose tissue combustion. However, its spectrum of health-promoting properties is much wider; first of all it shows nootropic, neuroprotective and antioxidant properties.
Few people known that ALCAR increases also the number of androgenic receptors (AR) and their sensitivity to testosterone. Because of that, it will be beneficial for people who use anabolic-androgenic steroids or hormone replacement therapy (HRT), as it can positively affect the effectiveness of such measures.
Because of the wide application of the product, its dosing and combination with other supplements should be adjusted to the desired effect. Procognitive action is possible already with a daily dose of 500–1,000 mg, lipolysis support – about 2,000 mg a day, making AR more sensitive – up to 3,000 mg of acetyl L-carnitine a day.
The supplement can be effectively combined with i.a. choline, alpha-lipoic acid, alpha GPC, PQQ, caffeine, vitamin B12 or L-theanine, depending on the effects you want to achieve.
Apollo’s Hegemony is a manufacturer of dietary supplements whose composition is based on the latest scientific research and experience. The company is constantly expanding its range of products and taking care that they are of top quality.
It offers formulations which have multiple effects on the body and those with more targeted effects – e.g. boosting alertness and focus, increasing the tolerance to stress, promoting peaceful sleep and maintaining the health of the liver and adrenal glands.
Dietary supplements by Apollo’s Hegemony are effective owing to carefully selected composition which comprises the most potent forms and their precise doses. What is more, herbal supplements contain standardised extracts.
All products of this brand comply with good manufacturing practices (GMP) and their ingredients are vegan and vegetarian friendly.
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|per 1 capsule||amount||%RDA|
|Acetyl L-Carnitine HCl||550 mg||-|
Microcrystalline cellulose, rice flour, gelatin (capsule shell).
The product has not been tested for substances banned by the World Anti-Doping Agency (WADA).
L-carnitine is a vitamin-like substance, synthesized in the body from amino acids (lysine and methionine) and available in foods of animal origin. It is a component of muscle (including cardiac muscle) and nerve tissue. Involved in the metabolism of fats affecting the transport of long-chain fatty acids into the mitochondria of the cell, facilitating their burning and energy production. It is a potent antioxidant, contributing to the improvement of the aerobic condition and accelerating the recovery after intense exercise. Recommended for use for representatives of endurance sports. In the sports supplementation there are available mono-preparation of carnitine (in liquid form, acetylated [ALC], esterified [see. Propionyl-L-carnitine]) and multicomponent (e.g. in a complex with organic acids - see. L-carnitine tartrate) energetic, weight loss and improving the exercise capacity supplements, to be purchased at www.muscle-zone.pl
Dosage: 1 - 3 g per day in 1 - 3 doses, preferably about 45 - 60 minutes prior to exercise.
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