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Life Extension Adrenal Energy Formula is a dietary supplement containing the new formula, which aims to alleviate the effects of stress, as well as to increase resistance to stressors. This formulation combines four effective extracts from medicinal plants, ie. Holy Basil, Cordyceps, Brahmi and Ashwagandha, which support the body's homeostasis and the functioning of the adrenal glands, and regulate the hypothalamic-pituitary-adrenal axis (HPA).
Holy Basil (Ocimum sanctum; Tulsi) – a medicinal plant used in traditional Chinese and Indian medicine. It contains many biologically active substances, including methyleugenol, eugenol, alpha and beta-caryophyllene, bisabolol, metylochawikol, linalool, 1,8-cineole, and ursolic acid. It exhibits adaptogenic, anxiolytic, antidepressant, immunomodulatory and homeostatic properties.
In 2008, there was a clinical study on 35 people who had to assess the effectiveness of the Holy Basil in a generalized anxiety disorder (GAD). Subjects were given 500 mg of extract from the leaves twice a day after meals for a period of two months.
The results were evaluated on the basis of a modified Hamilton’s Depression Scale Measurement, which indicated that patients had decreased symptoms of stress and feelings of anxiety. In addition, the subjects showed a better ability to focus and to adapt to changing conditions. The researchers conclude that the mechanism of action of Holy Basil based on the regulation of the HPA axis.
Ashwagandha (Withania somnifera) – a medicinal plant used in traditional Eastern medicine, called an Indian ginseng due to its adaptogenic properties. In ayurveda it is regarded as a cure for rheumatism, exhaustion, sexual impotence, and memory impairment.
Anxiolytic properties of Ashwagandha was confirmed by a randomized clinical trial of double blind test and placebo-controlled methods in patients suffering from anxiety. The dosage was 500 mg extract withania somnifera per day in two divided doses.
Ashwagandha is widely used as a sedative, calming and bringing healthy sleep preparation. It allows the organism to adapt to stress factors, so that it returns to homeostasis, despite the impact of stressors. It restores a dysregulated body to function properly, despite a poor diet, lack of sleep or physical, or mental fatigue.
Cordyceps – a species of mushrooms originating in the high mountain areas of Tibet known as Himalayan Viagra due to the properties that increase sexual performance. It is classified as adaptogens, so herbal substances (extracts) supprting the body's resistance to stressors and traumatic experiences, used in states of fatigue or anxiety. It contains many bioactive components including adenosine, cordycepin, vitamins (E, K, B1, B12), phytosterols, flavones, nucleosides, beta-glucans, and several minerals.
Bacopa Monnieri (Brahmi) – a medicinal plant commonly used in Indian and ayurveda medicine. It includes a plurality of active substances, including steroidal saponins, and alkaloids. It is recommended for use in children as a tonic for the brain, and because of its ability to stimulate the development of the nervous system.
The mechanism of Bakopa’s action is quite broad, difficult to understand, and not completely understood. It is known that active ingredients impact mainly on the limbic system (hippocampus), which is an overriding system, steering the basic mechanisms of behavior. The hippocampus is also heavily involved in the processes of learning and remembering.
It was demonstrated that Brahmi increases the number of cells and neural connections in the brain area, thereby improves cognitive and memory, association processes, as well as the reproduction of information. This plant can also be used in neurodegenerative diseases, including Alzheimer's, and Parkinson's disease.
In summary, Life Extension Adrenal Energy Formula is a dietary supplement with a broad spectrum of action, designed for anyone who wants to maintain energy and vitality, and also to protect the body against the effects of stress. The product contributes to restoring the systemic balance, and regulates the functioning of the hypothalamic-pituitary-adrenal axis.
It is recommended to use the product before stressful situations or during the period of increased stress to improve the body's adaptive mechanisms. The ingredients contained in the product have sedative properties so it is recommended to people who have problems with sleep, as well as people who want to support the adrenal glands. Due to the sedative effects it is best taken in the evening.
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|per portion (2 capsules)||amount||%DV|
|OciBest® Holy Basil extract 10:1 (whole plant) [std. to 2.5% triterpene acids]||600 mg||-|
|Proprietary Blend:||516 mg||-|
|Sensoril® Ashwagandha extract 5:1 (root and leaves) [std. to 32% oligosaccharides, 10% withanolide glycoside conjugates]|
|Cordyceps (Paecilomyces hepiali) extract 8:1 (mycelia) [std. to 7% cordycepic acid]|
|BaCognize® Ultra Bacopa extract 25:1 (whole herb) [std. to 25% bacopa glycosides]|
vegetable cellulose (capsule), microcrystalline cellulose, maltodextrin, stearic acid, silica.
Proprietary blend - is a complex of bioactive ingredients in the proportions, which are covered by the manufacturer's patent. According to the law in force in Poland, the components of the blend are known, and , by the place on the packaging, you can identify which components are in bigger amount (the components are listed in the decreasing order of amounts).
Proprietary blends are used in many food supplements, such as creatine stacks, no-boosters, fat burners and pro-testosterone supplements, improving libido.
Sensoril® is an ashwagandha extract (Withania somnifera), patented by Natron Inc. For the production of the extract, a mixture of roots and leaves of the plant is used to obtain a diverse and broad biochemical profile. The technological process itself includes only aqueous extraction and occurs without the use of alcohol or chemical solvents. Sensoril® is standardized for the content of three main groups of ingredients: withanolide glycosides, oligosaccharides and withaferin A.
More than 10 clinical trials have been conducted on humans to confirm the safety and beneficial effects of Sensoril® on mental performance, psychological well-being and physical strength. It has been proven, among others, that Sensoril® shows an anti-stress effect, it may raise energy levels, it favors better mood, adds vitality and reduces fatigue. In addition, it improves psychomotor skills, shortens reaction time and sharpens the senses. It also has pro-health properties – helping to regulate blood pressure and lower cholesterol.
On the market, there are plenty of mono-preparations with Sensoril®. Nevertheless, it also occurs as an additive to other compounds – it can be found in nootropic blends and formulas supporting the fight against stress.
Dosage: no standards for unit consumption.
The patent owner declares that the positive effects can be noticed already at a 125-mg dose a day.
Ashwagandha (Wythania somnifera / Indian ginseng) - a plant of the nightshade family, used in Oriental medicine as a means of adding vitality, improves the psychophysical condition. It is used as an aphrodisiac. The root of the plant is a rich source of bioactive compounds (phytosterols, glycosides, withanolides etc.). The sports supplementation, herbal preparations, a positive effect on the nervous system (reduces stress, and accelerates the adaptation to changing conditions psychophysical), hematopoietic and immune systems. It has a decisive influence on the process of synthesis of nitrogen oxides and the level of certain hormones, including testosterone (e.g. improving sexual functions).
Ashwagandha (Withania somnifera) is a component of the complex herbal supplements (as well as sets of adaptogens) increase the level of the male sex hormone (testosterone), supporting the sexual function of the body, supporting regeneration and having a calming effect.
Dosage: 300-600 mg of extract per day.
BaCognize® is an innovative, patented extract from above-ground parts of Bacopa (Bacopa monnieri), designed by Verdure Sciences®. It has a high safety profile and is known for its extremely strong nootropic properties. Published clinical trials with the participation of people from various environments (including students of medicine, professional soldiers, doctors) have confirmed the beneficial effect of BaCognize® on cognitive health and psychological well-being.
In scientific research, it has been proven that only some of the glycosides present in the above-ground parts of Bacopa are able to bind to serotonin receptors (5-HT1a, 5-HT2a and 5-HT3a), which have a significant impact on cognitive function. Most standardized Bacopa monnieri extracts contain various glycosides, so the effects of their use are not spectacular.
Using high-performance liquid chromatography (HPLC), Verdure Sciences® has isolated from only those glycosides present in the herb that have an actual effect on serotonin receptors. They have been named SABG (serotonin-active bacopa glycosides). BaCognize® is standardized for these glycosides.
BaCognize® is recommended for people who are particularly interested in improving such parameters of cognitive functions as memory, acuity of the senses, concentration, response speed, resistance to stress.
Dosage: a dose of 300 mg to 600 mg per day was used in clinical trials.
Glycocyamine - is a glycine derivative belonging to the guanidino compounds and the precursor of creatine synthesized intra-corporeally and affects the level of creatine during its supplementation (and after its completion). Glycocyamine is involved in the transformation, which takes place with the participation of S-adenosylmethionine, and may influence the development of unbeneficial homocysteine (increasing the risk of developing atherosclerosis). To neutralize the effects of homocysteine, supplementation is enriched with betaine. In the sports supplementation is available in many preparations of creatine.
Dosage: No strict standards of consumption, usually recommended in the sport, always with a combination of betaine
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