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In the last batches of Apollo's Hegemony products, another glue was used for lids under the caps. The glue is weaker than previously used, this is why the lid often stays inside the cap when unscrewing the bottle. This does not affect the quality of products because during storage the lid adheres to the bottle and protects its contents.
Apollo’s Hegemony NALT is a dietary supplement with nootropic properties, containing an acetylated and, therefore, a more soluble and assimilable form of L-tyrosine. The preparation helps to increase the level of some neurotransmitters, thanks to which it supports the functioning of brain cells, has a beneficial effect on well-being, increases energy levels, and improves memory and concentration, particularly in stressful situations.
The preparation has been additionally enriched with pyridoxal 5’-phosphate, the active form of vitamin B6 which enhances its nootropic effects.
NALT (N-acetyl L-tyrosine) is an acetylated form of the amino acid L-tyrosine, which is used mostly in order to increase cognitive functions, stimulate the functioning of the brain, improve communication between neurons, and alleviate the symptoms of stress.
Pyridoxal 5'-phosphate (P-5-P) is the active form of the water soluble vitamin B6. It acts as a coenzyme in many key metabolic reactions, related mainly to metabolism of amino acids, e.g. transamination, decarboxylation and deamination. What is more, this form of the vitamin is crucial in the metabolism of proteins, fats and carbohydrates.
Owing to antispasmodic and anti-inflammatory effects, P-5-P promotes healthy muscle and joint function. It is involved in energy production processes and thus increases your vitality and performance. This important especially for athletes and physically active individuals.
NALT as a highly bioavailable form of L-tyrosine
L-Tyrosine is an amino acid synthesised from phenylalanine in physiological conditions. L-Tyrosine is a crucial precursor for the synthesis of melanin, thyroxine, and neurotransmitters called catecholamines, such as dopamine and norepinephrine.
L-Tyrosine supplementation can have an essential therapeutic effect in the case of depression, cognitive disorders, memory problems, or a low mood.
How does L-tyrosine work?
L-Tyrosine has a beneficial effect on the organism through many different mechanisms; however, the one of the highest clinical importance is its role in the synthesis of neurotransmitters. L-tyrosine is a dopamine and norepinephrine precursor, so it stimulates the central nervous system, helps to improve psychophysical stability, stabilises emotional processes, and improves the mood.
L-Tyrosine is also used for the production of two thyroid hormones – thyroxine (T4) and triiodothyronine (T3), thanks to which it can be of crucial importance in regulating the right functioning of the thyroid gland.
Moreover, it takes part in the production of melanin – a colourant in the skin and hair that protects them from the harmful activity of ultraviolet rays; it also exhibits neuroprotective properties.
Antidepressant effect of L-tyrosine
The neurochemistry-based theory of depression suggests that there is an important correlation between a patient’s mood and a drop in serotonin, noradrenaline, dopamine, and GABA. The role of L-tyrosine, a substance that constitutes a precursor for dopamine and noradrenaline, makes it a potential efficient anti-depressant agent.
L-Tyrosine as a dopamine and noradrenaline precursor
L-Tyrosine is a substrate in the production of dopamine and noradrenaline. In order to understand the symptoms of their deficiency better, one needs to get familiar with their functions in the organism first.
Dopamine is produced in dopaminergic neurons that form the so-called dopaminergic systems. The two that we know the best are: the substantia nigra – striatum (motor function regulation), and the mesocorticolimbic system (the processes of learning and remembering, control over emotional and motivational activity). Disorders in the functioning of the dopaminergic system in the brain can lead to central nervous system diseases, such as Parkinson’s disease or schizophrenia, or play an important role in the development of an addiction to narcotic drugs.
Noradrenaline (norepinephrine) is produced in the adrenal medulla and in the synapses of sympathetic nerves. The main cluster of noradrenergic neurons is a nucleus called the locus coeruleus, which is connected with the hypothalamus. As a result of a response to stress, the functioning of the connection is distorted, which is why proper levels of the neurotransmitter are so essential during strong stress. Noradrenaline deficiency in the organism contributes to motivation deficits, the deterioration of the ability to remember, and a worse mood.
To sum up, Apollo’s Hegemony NALT is a dietary supplement containing high-quality acetylated form of L-tyrosine, whose acetylation allowed to obtain a more bioactive form than the traditional form that didn’t undergo the process.
The preparation is recommended particularly for people who need support for their mental and physical capacity, mood stabilisation, and a memory and motivation boost. It can prove particularly helpful in times of fatigue or exhaustion of the organism, not only physical, but also emotional, as well as in the case of excessive or frequent exposure to stress factors.
Using the preparation can bring additional benefits, such as better thyroid function in the case of hypothyroidism.
It is recommended to take the preparation 30-60 minutes before an anticipated stressful situation and/or before intellectual or physical effort. According to scientific observations, the best stress-reducing doses of L-tyrosine are 100-150 mg/kg of body mass consumed about an hour before the stressor; however, in the case of the acetylated forms, much smaller doses are advised because of their high assimilability – 300-500 mg a day. Do not exceed the dosage of 1,000 mg of N-acetyl L-tyrosine a day.
When using higher doses, you might experience some gastric problems. In that case, it is a good idea to split the dosage into two portions and take one 60 and the second one 30 minutes before an anticipated stress factor.
Apollo’s Hegemony is a manufacturer of dietary supplements whose composition is based on the latest scientific research and experience. The company is constantly expanding its range of products and taking care that they are of top quality.
It offers formulations which have multiple effects on the body and those with more targeted effects – e.g. boosting alertness and focus, increasing the tolerance to stress, promoting peaceful sleep and maintaining the health of the liver and adrenal glands.
Dietary supplements by Apollo’s Hegemony are effective owing to carefully selected composition which comprises the most potent forms and their precise doses. What is more, herbal supplements contain standardised extracts.
All products of this brand comply with good manufacturing practices (GMP) and their ingredients are vegan and vegetarian friendly.
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Microcrystalline cellulose, rice flour, capsule shell.
The product has not been tested for substances banned by the World Anti-Doping Agency (WADA).
Tyrosine - endogenous amino acid (synthesized within the body), one of the 22 protein amino acids building. It occurs naturally in animal food products (eggs, dairy, meat). If the deficiency, it can be synthesized by hydroxylation of phenylalanine, capable of being converted to tyrosine in the liver. It is a precursor of neurotransmitters: dopamine (the group of catecholamines, participating in the processes occurring in the nervous system, causing muscle coordination and participates in the synthesis of many hormones) and noradrenaline (counteracting stress, stimulating the heart and circulatory system, and increasing glycogenolysis and lipolysis participating in the processes of energy transformations). Tyrosine is a precursor of thyroid hormones responsible for the rate of change in metabolic processes and pigment (melanin). In the supplementation, preparations containing tyrosine are used in programs reducing body fat (weight loss), improve mood and are stimulants.
Dosage: Customarily 500-2000 mg per day.
Pyridoxal 5-phosphate (P-5-P) - the form of vitamin B6, called coenzymatic, considered the best assimilable form of this vitamin by the human organism. This is related to direct metabolic activity of pyridoxal-5-phosphate in the human organism. It does not have to be subjected to biochemical transformations in the organism in order to be able to enter metabolic pathways as a biologically active ingredient.
Vitamin B6 is an incredibly important factor regulating the work of many processes in the organism due to its role in the organism as a coenzyme, essential for the activation of many important enzymes. Thanks to this, it regulates metabolism at many levels and its proper supply is conducive to maintaining homeostasis of the organism.
Another aspect of effectiveness of vitamin B6 is its influence on the normalization of emotional states. It is conducive to relaxation, facilitates falling asleep and falling in a deep, the most valuable sleep. Special influence on P5P on the psyche is proven in women before menstruation, as it demonstrates considerable ability to reduce the symptoms of the pre-menstrual syndrome.
Supplementation with vitamin B6 also demonstrates positive influence on the functions of the nervous system. It is conducive to the nourishment of neuronal tissues and optimizes the secretion of neurotransmitters, thanks to which it promotes nervous transmission and demonstrates neuroprotective properties. It was proven that vitamin B6 may decrease the risk of developing Parkinson’s disease.
Some sources also suggest the ability of pyridoxal 5-phosphate to reduce the risk of cancer. This effectiveness is noted especially in relation to breast cancer.
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