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Sup3r-4 Sup3r-4 60 caps.
Olympus Labs
71.17 $

Sup3r-4 60 caps.

Servings: 60 caps.
1-2
Location:
EU Stock
Availability:
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For free shipping is missing: 80.00 $
71.17 $With VAT
1.19 $ / serving

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Description
  • Non-Methylated/Non-Liver Toxic (Doesn't require liver support such as TUDCA or NAC)
  • Wet Compound
  • Increases Energy/Combats Lethargy
  • Increases IGF-1 & GH
  • Increases Overall Sense of Wellbeing/Mood
  • Increases Recovery
  • Increases Size/Muscle Mass (Increased Nitrogen Retention)
  • Increases Strength
  • Supports Libido
  • Supports Joints
  • Excellent Test Base
  • Excellent for Bulking/Recomping/Cutting
  • Excellent Stacker

4-Andro, also known as 4-Androsterone, 4-DHEA, 4-Dehydroepiandrosterone, 4-Androstene-3b-ol,17-one and 3b-Hydroxy-Androst-4-ene-17-one is a naturally occurring DHEA isomer first artificially synthesized 80 years ago in 1936 by Nobel prize-winning Croatian chemist Leopold Ružicka, who also first successfully synthesized Testosterone. Structurally it closely resembles DHEA, but the double bond in the 4th position rather than the 5th significantly changes its effects, making it less estrogenic by not acting directly upon the estrogen receptor like DHEA is capable of. It can aromatize to estrogen, though it is unlikely to do so at any considerable amount which may cause estrogenic side effects. The mild estrogen conversion can be easily balanced with a non-aromatizing prohormone like Epiandrosterone or 1-Androsterone. 

Most notably 4-Androsterone is a non-methylated (non-17a-alkylated) precursor/prohormone to Testosterone, through a two-step conversion process in vivo by the enzymes 3ß-hydroxysteroid dehydrogenase (3ß-HSD) and 17ß-hydroxysteroid dehydrogenase (17ß-HSD). There are two possible pathways of conversion, both requiring two conversion steps each to transition from 4-Androsterone to Testosterone. One conversion pathway for 4-Androsterone is to be converted by 3ß-HSD into 4-Androstenedione (androst-4-en-3,17-dione) and then converted by 17ß-HSD into Testosterone. And another conversion pathway for 4-Androsterone is to be converted by 17ß-HSD into 4-Androstenediol (3ß,17ß-dihydroxy-androst-4-ene) and then converted by 3ß-HSD into Testosterone. As with Epiandrosterone, it is quite difficult to calculate percentages for conversion rates regarding 4-Androsterone due to the fact that these conversions are reversible, as 4-Androsterone can convert to Testosterone, and Testosterone can also convert to 4-Androsterone.

One of 4-Androsterone's two main metabolites, 4-Androstenedione, has been found to possess estrogenic actions, similarly to other DHEA metabolites. The second of 4-Androsterone's main metabolites, 4-Androstenediol, also known as 4-AD, also is capable of conversion to estrogen, since Testosterone is the metabolic precursor of the estrogens in the male body. Both 4-Androstenediol and 4-Androstenedione have androgenic effects, acting as weak partial agonists of the androgen receptor. However, due to their lower intrinsic activity in comparison, in the presence of full agonists such as Testosterone or Dihydrotestosterone (DHT), they have antagonistic actions, behaving more like anti-androgens. This however does not seem to negatively impact their anabolic abilities.

Both 4-Androstenedione and 4-Androstenediol convert to 4-Androsterone's target hormone, Testosterone. Testosterone is a steroid hormone from the androgen group and is found in humans and other vertebrates, it is the principal male sex hormone and an anabolic steroid. It is one of the most well studied hormones, and is used as the standard by which other androgens are measured against, with an Anabolic:Androgenic ratio of 100:100. Testosterone has a multitude of effects, and is responsible for a large amount of functions in the human body include sexual, psychosexual, and regulation of overall musculature. A non-exhaustive list of positive effects associated with Testosterone includes muscle size, strength, sexual satisfaction, erectile function, libido, vigor, mood, concentration, verbal memory, IGF-1 levels, and so on. Testosterone is capable of converting to Dihydrotestosterone via the 5a-reductase enzyme, as well as aromatizing via the aromatase enzyme to 17b-estradiol.

Though 4-Androsterone has many beneficial effects, it is not without the possibility of side effects. On a positive note, 4-Androsterone is non-methylated (non-17a-alkylated) so there should be little to no concern regarding it negatively affecting the HDL/LDL ratio to the same extent other prohormones can. Because it can aromatize, the possibility of bloating, water retention, or sensitive nipples does exist, however the incidence of these side effects is anecdotally very low. If such side effects occur it is recommended to lower the dose or discontinue use. Other side effects such as oily skin, acne, reduced fertility or increased hair shedding are possible, though considered mild and temporary. It is possible that 4-Androsterone may cause some HPTA suppression, and therefore it is always recommended to run a properly planned Post-Cycle Therapy (PCT) following any supplementation regimen containing 4-Androsterone.

It is worth noting that 4-Andro, just as with Epi-Andro and 1-Andro, undergoes significant first-pass metabolism in the liver. This, in addition to other factors, contributes to the low bioavailability of 4-Andro. There are many delivery systems that have been utilized in attempts to enhance bioavailability, with the most recent advancements being with the pharmaceutical delivery system commonly abbreviated as S-SEDDS which stands for Solid Self-Emulsifying Drug Delivery Systems. S-SEDDS enhances absorption via the intestinal lymphatic system which circumnavigates the destructive hepatic first-pass metabolism.

4-Androsterone is an excellent addition to almost any cycle and though it will not elicit identical results to injectable Testosterone, it is the most effective legal precursor to Testosterone currently available on the market. It has tremendous synergy with prohormones like 1-Androsterone as the Testosterone mitigates the lethargy and low libido issues that can occur. Low estrogen levels can be an issue on cycle for many men, and is a well-known factor in lower libido, dry skin and even joint pain. The small amount of estrogen 4-Androsterone can add to your cycle helps keep you functioning at your best, and feeling well. Its conversion percentage to estrogen is highly variable, and though it is highly uncommon, if estrogenic side effects arise the dosage can be lowered to offset. Although infrequently used alone, and most commonly seen in a stack, older men anecdotally report great success running solo 4-Androsterone cycle. The results for 4-Androsterone cycles will be similar to the original “4-AD” which was reclassified as a Schedule III drug in 2004 due to an amendment of the Anabolic Steroid Control Act in the United States. This means it will produce fairly lean gains in muscle mass, cause notable improvements in strength with low incidents of bloat or water retention from estrogen conversion. Any water retention is typically beneficial, manifesting in non-aesthetic ways such as adding to strength and supporting joints.

Directions for use
Manufacturer
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Composition

Container size: 60 capsulesServing size: 1 capsuleServings per container: 60
per 1 capsuleamount%DV
4 androstene-3b-ol, 17-one110 mg-

Other ingrednients

LipoAbsorb Matrix: Phospholipids from NON-GMO Soy Lecithin: Phosphatidylocholine, Lysophosphatidylcholine, Phosphatidylethanolamine, Phosphatidylinositol and Phosphatidylserine in caprylic/capric triglycerides, Medium Chain Triglycerides, Glyceryl Stearate, Oleic Acid, Linoleic, and Linolenic Acids, Microcrystalline Cellulose, Carboxymethylstarch Sodium Salt, Labrasol, Poly ethylene Glycol, Colloidal Silica Anhydrous, Magnesium Stearate.

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