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Hi-Tech Pharmaceuticals Arimistane is a preparation with a strong anti-estrogen and anti-cortisol activity. It increases testosterone levels and as an aromatase inhibitor protects against excessive levels of estrogen. The preparation effectively facilitates the reduction of adipose tissue and the building of muscle mass, improves regeneration and increases libido.
Arimistane® contained in the product is a registered trademark compound characterized by a high-quality and the purity exceeding 98.5%. Additionally, the patented Cyclosome ™ formula ensures high bioavailability of the substance and allows it to pass right into the bloodstream excluding it from the first-pass metabolism in the liver.
Orally-administered hormones and their derivatives often have no effect as they are rapidly metabolized by the liver and excreted from the body. The use of a water-soluble complex of cyclodextrin prohormone placed in liposomes ensures high bioavailability and delivery of prohormone to the circulatory system through the intestinal and lymphatic route.
Arimistane (Androsta-3,5-diene-7,17-dione), also known as 3-deoxy-7-oxo-DHEA, is a metabolite of 7-Keto DHEA, a naturally occurring hormone formed from dehydroepiandrosterone. Although it is a derivative of DHEA, it displays a different activity in the body. It is classified as a prohormone and is often used when taking anabolic-androgenic steroids (AAS) or after their discontinuation (PCT).
Armistane as an aromatase inhibitor
Aromatase is an enzyme that converts testosterone circulating in blood testosterone to estrogens. Although certain amounts of female hormones are necessary for men, their excess is not desirable. The excess of estrogen negatively affects the figure, contributing, among others to collecting water and adipose tissue in the area of the chest and hips. It makes the building of muscle mass more difficult, reduces libido and leads to sexual dysfunctions. In addition, it negatively affects metabolic health.
Men with excessive body mass or with genetic predispositions, as well as individuals using AAS are particularly susceptible to excessive aromatization, as large amounts of androgens administered from the outside intensify the conversion to estrogens.
Arimistane has a high affinity for the aromatase enzyme, but it does not undergo catalytic activity. This way, Arimistane blocks the aromatase activity and the conversion of androgens to estrogens. A high level of testosterone is essential for maintaining health, muscle mass, libido and high regenerative abilities in men. It also reduces the accumulation of fat and is responsible for a good mood and motivation.
In addition, high levels of estrogen contribute to the reduction of androgen production. A feedback reaction that follows is that estrogen reduces the frequency of pulsatile gonadoliberin release (GnRH) and reduces the sensitivity of the pituitary gland to this hormone. GnRH stimulates the pituitary to release lutropin (LH) and follicle stimulating hormone (FSH) - the hormones responsible for the proper functioning of the gonads and the production of testosterone.
Arimistane regulates the hormone balance of men being on a cycle. It also has the property of raising natural testosterone production, so it is also used as so-called " an unblock" after androgen treatment.
Anti-cortisol properties of Armistane
Cortisol – a hormone released in response to stressors (physical, psychological, physiological), which is an enemy of all individuals watching their figure. Cortisol promotes the accumulation of fat in the lower abdomen, retention of water in the body, affects the cognitive functions and hinders building of muscle mass, and even promotes catabolism.
In addition, cortisol and testosterone levels are highly dependent on one another. If the body produces too much of cortisol, it can lead to a reduction in testosterone production. Long-term stress (including an intensive workout at the gym) may lead to a disruption of the balance between cortisol and testosterone. Since both hormones are synthesized from pregnenolone, an excessive production of cortisol will disrupt testosterone synthesis.
Arimistane as a metabolite of DHEA reduces cortisol levels by affecting the activity of 11β-hydroxysteroid dehydrogenase type 1 (11βHSD1). 11βHSD1 is responsible for converting biologically inactive cortisone into active cortisol, and to a lesser extent for the reverse reaction. Reduction of 11βHSD1 enzyme activity decreases the production of cortisol and helps to maintain a hormonal balance between androgens and stress response hormones. As a result, maintaining an athletic figure, sexual performance, as well as an improvement of life quality, become easier.
In conclusion, Hi-Tech Pharmaceuticals Arimistane is a high-quality anabolic and anti-catabolic preparation. It helps to lower cortisol levels and stimulates the pituitary gland to produce LH and FSH, which contribute to the increased production of androgens. It provides estrogen reduction during the cycle, as well as support after its completion.
The prohormone is relatively safe and does not display any serious side effects, however, symptoms such as gastrointestinal disorders, dry mouth, fatigue or weakness may occur.
Dosage should be suited to individual current blood test results, because the excessive lowering of estrogen levels can cause sleep problems, irritability, low blood pressure and even erection problems.
In order to support the natural production of testosterone, followed the cycle, it is recommended to combine the product with HCG.
The company Hi-Tech Pharmaceuticals was founded 1994 and it has grown to be a leader in the industry. It creates, manufactures and sells high-quality herbal products sold by the large, major retailers across the United States. The company has 45 supplements that develop muscle and strength, fat loss, sexual performance and healthcare. All products are aimed at improving life-quality and our supplements have unmatched in quality and efficacy. All their products are designed to improve the quality of life, and supplements are second to none in terms of quality and effectiveness. Hi-tech is a response to the needs of women and men, from active lifestyle to good sports condition. Hi-Tech Pharmaceuticals produces better products than the competition. Try it and you will not be disappointed.
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|per portion (1 tablet)||amount||%DV|
|Androsta-3,5-diene-7,17-dione (as Arimistane®)||50 mg||*|
Microcrystalline Cellulose, Phosphatidylcholine 75%, Hydroxypropyl Beta Cyclodextrin, Phytosterols, Magnesium Stearate, Silica, FD&C Blue #2, FD&C Red #40.
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