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Aliness Niacin is a dietary supplement containing niacin in the form of an amide of nicotinic acid. Niacin is an essential ingredient for the proper functioning of the body. It primarily influences optimal energy metabolism, cardiovascular health and psychological well-being. The product is suitable for vegans.
Niacin, also known as vitamin B3 or PP, is a water-soluble vitamin occurring in the form of nicotinic acid or an amide of nicotinic acid. Nicotinic acid amide is a biologically active form.
Niacin contribution to cellular metabolism
Niacin is a precursor to nicotinamide adenine dinucleotide (NAD +) and its phosphorylated form (NADP +). NAD +, as an electron transporter, is necessary for the oxidation and reduction reactions that result in the production of cellular energy. It is also part of the non-oxidoreductases. In turn, NADP + participates in the reactions of biosynthesis of important for the body molecules.
Niacin as a drug modifying blood lipids
Niacin has a major effect on the metabolism of lipoproteins and blood lipids. In pharmacology, it is used as a medicine modifying blood lipids in the treatment of dyslipidemia, including dyslipidemia associated with type 2 diabetes and insulin resistance. Niacin has been proved to significantly reduce in LDL lipoprotein, lipoprotein (a) and triacylglycerol levels as well as increase HDL lipoproteins, i.e. good cholesterol.
The ability to lower lipoprotein (a) is a unique property of niacin that is not showed by most other drugs. Lipoprotein (a) is a form of LDL. It contributes to the formation of blood clots, intensifies LDL oxidation and affects the worsening of the expansion of blood vessels, thereby increasing the accumulation of cholesterol in their walls.
The effects of niacin on the nervous system
Vitamin B3 is essential for the proper functioning of the nervous system. Its deficiency may manifest itself, among others, by insomnia, memory impairment and emotional distress. Niacin has been also proven to have beneficial effects in case of depressive disorders and schizophrenia.
Anti-migraine properties of niacin
There are more and more reports indicating the efficacy of niacin in the fight against migraine and headache, as well as in the prevention of these ailments. Intracranial vessel narrowing causes migraine aura symptoms and headache. Niacin is capable of vasodilation due to its effect on the production of prostaglandin D2, which is why it may reduce these symptoms and prevent their recurrence. Another mechanism of prophylactic action of vitamin B3 is its effect on proper energy metabolism, which is responsible for optimal blood supply and access of cerebral vessels to oxygen.
In summary, Aliness Niacin is a preparation aimed at supplementing vitamin B3 deficiencies in the diet, especially recommended to support normalization of blood lipid profile, protect the cardiovascular system, maintain normal energy metabolism, and also as a painkiller.
Some highly sensitive persons may experience skin redness (the so-called niacin flush) after taking niacin in a greater dose than 20 g per day.
When supplementing higher doses of B vitamins, remember to drink the correct amount of water during the day. This will allow the excretion of any excess of these water-soluble vitamins in the urine.
Aliness is a Polish brand owned by Medicaline. The company has advanced development and research facilities and meets the demanding European Standards of Production and Storage based on the pharmaceutical standard GMP and HACCP. A team of experienced specialists supervises the quality of manufactured dietary supplements. The company uses only the highest quality certified raw materials, often occurring in patented forms.
Aliness cooperates with the research laboratories accredited by the Main Pharmaceutical Inspectorate - SGS Poland and J.S. Hamilton Poland S.A., and also with the National Institute of Medicines, responsible for quality and safety control in research and development. Many Aliness products have an ecological certificate, which is a guarantee of the lack of use of artificial fertilizers, pesticides and chemical plant protection products at all stages of the production of the raw material.
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Vitamin B3 (vitamin PP, niacin, nicotinic acid, nicotinamide) is niacinamide niacin. It is used in interaction with vitamins B1, B2 and B6 in the synthesis of hormones during lactation. It provides proper functioning of the brain and nervous system. It is helpful in inflammatory conditions of the skin. Required for synthesis of sex hormone, estrogen, testosterone, cortisone, and insulin. It does not lose its properties in the manufacturing and storage. The source of acquiring vitamins PP are both products of animal origin (the lean meat, eggs, fish) and vegetable origin (dates, figs, hazelnuts, plums).
Dosage: 2-12 mg / day for children, 14 mg / day for women, 16 mg / day for men and 17-18 mg / day for pregnant or nursing women.
Nicotinic acid amide – also known as nicotinamide, belongs to a group of compounds referred to as vitamin B3, along with nicotinic acid and inositol hexanicotinate. It exerts its main biological activity as a precursor to two key coenzymes for efficient energy metabolism of the body: nicotinamide adenine dinucletodide and nicotinamide adenine dinucleotide phosphate. They are responsible for carrying hydrogen and electrons in the respiratory chain and thus facilitate efficient energy production by the human body.
Nicotinamide supplementation is recommended for active persons not only because of its ability to promote the body’s energy efficiency. It has also a beneficial impact on mind, increases tolerance to stressors and may reduce symptoms of depression. It is pointed out that niacin supplementation correlates positively with sleep quality.
Unlike nicotinic acid, nicotinamide does not show the ability to produce a “flush effect”, namely redness in the face caused by taking large doses of niacin. It has been also shown to influence partly cardiovascular function.
Nicotinamide is also indicated to influence beneficially the absorption of other B vitamins and vitamin D. This compound should be taken with caution by diabetics because it can increase the body’s demand for insulin.
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