Since 2005
You are currently:
Choose language:
Need help?
Leave message
Choose language:
Select currency: $ £
Since 2005
en
USD
Order:55.00 $111.00 $166.00 $222.00 $
Shipping:-3.00 $-6.00 $-8.00 $-11.00 $
0 0.00 $
Since 2005  sales@mz-store.com  +1 844-530-3647
Time-Release Niacin 500mg Time-Release Niacin 500mg

Doctor's Best Niacin Time-Released With Niaxtend is a dietary supplement which contains niacin in form of long-acting nicotinic acid, which is released for 8 hours, so that it prevents flush effects (sudden redness, feeling hot, tingle, itching of face, shoulders and breast). One tablet contains 500 mg of niacin.

Niacin (vitamin B3, vitamin PP) is an umbrella term for nicotinic acid and nicotinic acid amide which are substrates of the synthesis of a coenzyme, nicotinamide adenine dinucleotide NAD+, with its phosphorylated form, NADP+, which are necessary for the proper conduction of metabolic processes. It is one of the most durable vitamins, soluble in water or alcohol.

Niacin is essential for the proper functioning of the central and peripheral nervous systems, participates in the synthesis of hormones (thyroxine, insulin, sex hormones) as well as improves blood circulation. Properties of niacin result in a wide spectrum of its application in medicine.

Discovery of niacin
The discovery of this vitamin is associated with a diseases caused by its deficiency – pellagra (Alpine scurvy). In 1926, a hypothesis by Goldberger was presented. It said that the deficiency of a vitamin, which was known then as G or PP (“prevention of pellagra”), is caused mainly by improper eating habits – high consumption of corn (poor in niacin) and lack of meat in diet which is one of its main sources. Just after Goldberger’s death, his hypothesis was proven, which is why he was nominated for a Nobel Prize five times.

The consequences of niacin deficiencies
According to this, niacin deficiency can lead to a disease called pellagra or 3D disease, because of its main aspects – dermatitis (symmetrical rash in places exposed to sunlight, tongue inflammation), diarrhoea and dementia (neurological disorders – depression, memory losses, fatigue, apathy and headaches).

Risk factors of niacin deficiency
Risk factors of niacin deficiency include not only improper diet poor in niacin sources, but also chronic alcohol abuse and disorders of tryptophan metabolism (an amino acid which is transformed into niacin). Transformation of tryptophan into niacin is determined by a number of factors, i.a. hormonal activity, genes, individual differences; deficiency of vitamins B2 and B6 and iron as well as leucine excess slows down the transformations.

Reduction in migraine attacks and tension headaches
Niacin is used for the treatment of migraines and tension headaches. It has been observed that the vitamin contributes to dilatation of subcutaneous vessels, which reduces migraine symptoms, dilatates intracranial vessels and counteracts narrowing of the extracranial vessels. There are some evidences that niacin applied every day for preventive purposes supports the proper energy metabolism in mitochondria, so that it reduces the frequency of muscle tension and pain.

Support for antioxidant processes
Niacin shows antioxidant properties. An increase in NADH level in cells leads to increased activity of glutathione reductase, which plays a crucial role in supporting cells detoxification of H2O2. Moreover, niacin can inhibit lipids peroxidation and glutathione oxidation.

Maintenance of the proper lipid level in blood
Niacin supports stabilisation of lipid levels in blood. It has been demonstrated that nicotinic acid normalises concentration of all lipids and lipoproteins fractions in blood. The vitamin significantly reduces the levels of LDL cholesterol and triglycerides and at the same time raises HDL cholesterol level, so that it reduces the risk of development of atherosclerotic clot and coronary artery disease and supports treatment of dyslipidaemia, particularly in people with type 2 diabetes.

To sum it all up, Niacin Time-Released With Niaxtend is a dietary supplement which effectively complements vitamin B3 deficiency. The product is especially recommended for improving regulation of lipid parameters and for prevention of cardiovascular diseases, dyslipidaemia and type 2 diabetes. Moreover, it can be also effective in case of migraines and tension headaches. 

InStock
Since 2005
Add to Cart
Time-Release Niacin 500mg Time-Release Niacin 500mg 120 tab.
Doctor's Best
21.44 $

Time-Release Niacin 500mg 120 tab.

Servings: 120 tab.
1-2
Location:
EU Stock
Availability:
Small amount
Working days
from the dispatch
Minimum expiration date:
2024-02
For free shipping is missing: 68.00 $
21.44 $With VAT

From 3 units only 21.01 $ /Units. -2%

1 Units.
Add to Cart

Customer Service

(mon.-fri 900-1700

You have got questions about the product

Description
  • Anti-atherosclerotic and cardioprotective properties
  • Reduces migraine attacks and tension headaches
  • Supports transformations of proteins, fats and carbohydrates
  • Determines the proper functioning of nervous system
  • Promotes the proper energy metabolism
  • Helps to maintain lipid balance
  • Time-released tablets
  • Reduces the flushing symptoms

Doctor's Best Niacin Time-Released With Niaxtend is a dietary supplement which contains niacin in form of long-acting nicotinic acid, which is released for 8 hours, so that it prevents flush effects (sudden redness, feeling hot, tingle, itching of face, shoulders and breast). One tablet contains 500 mg of niacin.

Niacin (vitamin B3, vitamin PP) is an umbrella term for nicotinic acid and nicotinic acid amide which are substrates of the synthesis of a coenzyme, nicotinamide adenine dinucleotide NAD+, with its phosphorylated form, NADP+, which are necessary for the proper conduction of metabolic processes. It is one of the most durable vitamins, soluble in water or alcohol.

Niacin is essential for the proper functioning of the central and peripheral nervous systems, participates in the synthesis of hormones (thyroxine, insulin, sex hormones) as well as improves blood circulation. Properties of niacin result in a wide spectrum of its application in medicine.

Discovery of niacin
The discovery of this vitamin is associated with a diseases caused by its deficiency – pellagra (Alpine scurvy). In 1926, a hypothesis by Goldberger was presented. It said that the deficiency of a vitamin, which was known then as G or PP (“prevention of pellagra”), is caused mainly by improper eating habits – high consumption of corn (poor in niacin) and lack of meat in diet which is one of its main sources. Just after Goldberger’s death, his hypothesis was proven, which is why he was nominated for a Nobel Prize five times.

The consequences of niacin deficiencies
According to this, niacin deficiency can lead to a disease called pellagra or 3D disease, because of its main aspects – dermatitis (symmetrical rash in places exposed to sunlight, tongue inflammation), diarrhoea and dementia (neurological disorders – depression, memory losses, fatigue, apathy and headaches).

Risk factors of niacin deficiency
Risk factors of niacin deficiency include not only improper diet poor in niacin sources, but also chronic alcohol abuse and disorders of tryptophan metabolism (an amino acid which is transformed into niacin). Transformation of tryptophan into niacin is determined by a number of factors, i.a. hormonal activity, genes, individual differences; deficiency of vitamins B2 and B6 and iron as well as leucine excess slows down the transformations.

Reduction in migraine attacks and tension headaches
Niacin is used for the treatment of migraines and tension headaches. It has been observed that the vitamin contributes to dilatation of subcutaneous vessels, which reduces migraine symptoms, dilatates intracranial vessels and counteracts narrowing of the extracranial vessels. There are some evidences that niacin applied every day for preventive purposes supports the proper energy metabolism in mitochondria, so that it reduces the frequency of muscle tension and pain.

Support for antioxidant processes
Niacin shows antioxidant properties. An increase in NADH level in cells leads to increased activity of glutathione reductase, which plays a crucial role in supporting cells detoxification of H2O2. Moreover, niacin can inhibit lipids peroxidation and glutathione oxidation.

Maintenance of the proper lipid level in blood
Niacin supports stabilisation of lipid levels in blood. It has been demonstrated that nicotinic acid normalises concentration of all lipids and lipoproteins fractions in blood. The vitamin significantly reduces the levels of LDL cholesterol and triglycerides and at the same time raises HDL cholesterol level, so that it reduces the risk of development of atherosclerotic clot and coronary artery disease and supports treatment of dyslipidaemia, particularly in people with type 2 diabetes.

To sum it all up, Niacin Time-Released With Niaxtend is a dietary supplement which effectively complements vitamin B3 deficiency. The product is especially recommended for improving regulation of lipid parameters and for prevention of cardiovascular diseases, dyslipidaemia and type 2 diabetes. Moreover, it can be also effective in case of migraines and tension headaches. 

Directions for use
Manufacturer
Reviews (0)

Composition

Container size: 120 tabletsServing size: 1 tabletServings per container: 120
per 1 tabletamount%DV
Niacin (as nicotinic acid)500 mg3125%

Other ingrednients

Vegetable waxes (rice bran and/or carnauba wax), stearic acid, magnesium stearate (vegetable source), silica.

Similar products
Best to combine with
Jarrow Formulas
35.01 $

A formulation providing ubiquinol and pyrroloquinoline quinone, compounds promoting the mitochondria function.

Buy
Lab One
23.07 $

A three-component symbiotic preparation for active people. Shows anti-inflammatory effect.

Buy
Nature's Way
13.30 $

High dose of diosgenin – the „hormone of youth”; rich source of natural phytoestrogens.

Buy
Source Naturals
24.15 $

DIM has been shown to lead to the preferential formation of estrogen metabolites

Buy
Biotech Usa
9.23 $

Omega-3 acids obtained from fish oil, with vitamin E. The support for the nervous and circulatory systems.

Buy
Swanson
10.58 $

A highly-active nattokinase, which facilitates the dissolution of clots and promotes cardiovascular health.

Buy

Latest on blog

Squat Jump

Squat Jump

The squat jump is the ultimate combination exercise and it’s a real ass-kicker to boot, taking the mechanics of a squat and adding the power component of a...

Read more
Past Failure – who can train like that?

Past Failure – who can train like that?

It seems every day someone comes along with a new and improved system of weight training scientifically designed to stimulate the muscle fibres unlike any other...

Read more
To avoid migrene, use the proper diet!

To avoid migrene, use the proper diet!

An anti-migraine diet can help people who are struggling with migraine headaches. Migraine attacks can be caused by some foods and alcohol. There is also hunger...

Read more
Selenium and coenzyme Q10 increase IGF-1 concentration

Selenium and coenzyme Q10 increase IGF-1 concentration

IGF-1 is a key signaling molecule associated with growth hormone (GH) that increases protein synthesis in skeletal muscle. Mice modified for IGF-1 expression...

Read more
Apple a day keeps the doctor away!

Apple a day keeps the doctor away!

Apples and their healing properties were already known around 6500 B.C. in the region between the Black Sea and the Caspian Sea, where they come from. These...

Read more
Chronic Fatigue Syndrome

Chronic Fatigue Syndrome

Chronic Fatigue Syndrome (CFS), also known as Myalgic Encephalomyelitis, is a far cry from just feeling a little bit tired. It’s a debilitating and...

Read more

Sign up for our newsletter
And receive coupons, news, special offers and much more!

Customer service

MZCatalog - recommended dietitians

MZCatalog - recommended trainers

MZCatalog - recommended clubs

Supps4You LLC
16192 Coastal Hwy Lewes, Delaware 19958
sales@mz-store.com +44 7767803657