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Aliness R-ALA is a dietary supplement which contains 200 mg of active substance ‒ alpha lipoic acid ALA in form of enantiomer R, characterised by high bioavailability. This organic chemical compound plays an important role in energy metabolism, shows antioxidant and anti-inflammatory properties as well as has wide health-promoting effect.
The majority of products with alpha lipoic acid contain a composition of two isomers of this acid ‒ R and S. However, it turns out that the enantiomer S is actually useless and it is hard to get it out from such a composition. When we buy an ALA supplement we cannot known the content of the R active form. Aliness R-ALA is free from the useless S-form and contains only pure enantiomer R, which is present in nature.
Alpha lipoic acid (ALA) can be produced by the body system, which is why it is not classified as a vitamin (as it was at the beginning). However, it acts similarly to vitamins. As a coenzyme, it plays an important role in glucose metabolism, has antioxidant properties and is necessary for the synthesis of acetyl-CoA, a compound involved in energy production. As it is both water and fat soluble, it is often referred to as a “universal” antioxidant.
Unfortunately, it is quite often that the amount of alpha lipoic acid produced by the body system is not sufficient to fully cover the demand. In such situation, it is recommended to use preparations containing active form of this substance, such as Aliness R-ALA.
Influence on energy metabolism
Alpha lipoic acid increases the uptake and use of glucose by cells as well as it is involved in its metabolism for energy purposes. Researchers assume that R-ALA has a positive impact on lipid profile and fat reduction. Such properties are quite interesting in case of a substance which is not a hormone. It is assumed that these result from the ability of alpha lipoic acid to enable the growth of energy expenditure and influence on appetite reduction.
Oxygen free radicals are regular by-products of metabolism. They can damage tissues if their excessive amounts are not reduced by antioxidants. A perfect antioxidant should have a wide impact on their action. Thanks to the fact that ALA can work in both aqueous and fatty environment, it acts at different levels (it is present in the tissues, cells and extracellular spaces) and supports the action of other antioxidants. For this reason, it is called a “universal antioxidant”.
The antioxidant properties of ALA affect cells, tissues and extracellular spaces. In the body system, alpha lipoic acid can be reduced to a strong mitochondrial antioxidant, dihydrolipoic acid (DHLA). DHLA can transform the oxidised glutathione into its reduces form, which then takes part in deactivation of oxygen free radicals as well as can regenerate the oxidised vitamin C, which in turn has the same effect on vitamin E. Both vitamins are strong antioxidants.
Influence on body system ageing
With age, our ability to synthesise lipoic acid declines. Ageing causes also the accumulation of oxidised proteins which interfere with the efficiency of mitochondria functions. It is commonly known that the decrease in functionality of mitochondria is one of the possible reasons for ageing. Apart from that, with age there is also a decline in liver possibilities in terms of regeneration of oxidised vitamin C. Scientific studies demonstrate that supplementation with R-ALA reverses this effect, partially restores mitochondria functions and reduces the influence of oxygen free radicals.
Cognitive skills and healthy nervous system
Body system ageing results in progressive damage to nervous system tissues, as fast metabolism and a long life of nerve cells make them very susceptible to the influence of oxygen free radicals. Thanks to its wide antioxidant properties, alpha lipoic acid can play an important role in the protection of the nervous system.
The cardiovascular system
R-ALA can have a positive impact on the cardiovascular system through several mechanisms. Scientific studies demonstrate that alpha lipoic acid positively influences the lipid profile and reduces fat level. Such effects result from ALA ability to increase energy expenditure and appetite reduction. Although the observations require further investigation, the researchers are very optimistic about the support for the proper functioning of the cardiovascular system, by maintaining an optimal body weight and promoting the proper lipid metabolism.
To sum it all up, Aliness R-ALA is a dietary supplement of wide health-promoting properties. Thanks to its "universal" antioxidant effects, it can be used to prevent cardiovascular diseases and to protect the nervous system. The decreasing with age production of endogenous ALA makes the product may be used in order to enter the old-age period without problems. Thanks to the positive influence of alpha lipoic acid on energy metabolism of carbohydrates, it is often recommended for sport supplementation and weight reduction.
Take 1-2 tablets a day, during a meal.
Aliness is a Polish brand owned by Medicaline. The company has advanced development and research facilities and meets the demanding European Standards of Production and Storage based on the pharmaceutical standard GMP and HACCP. A team of experienced specialists supervises the quality of manufactured dietary supplements. The company uses only the highest quality certified raw materials, often occurring in patented forms.
Aliness cooperates with the research laboratories accredited by the Main Pharmaceutical Inspectorate - SGS Poland and J.S. Hamilton Poland S.A., and also with the National Institute of Medicines, responsible for quality and safety control in research and development. Many Aliness products have an ecological certificate, which is a guarantee of the lack of use of artificial fertilizers, pesticides and chemical plant protection products at all stages of the production of the raw material.
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