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Apollo's Hegemony CDP Choline is a dietary supplement containing 300 mg of CDP-choline per capsule. CDP-choline, also known as citicoline, is a natural choline compound with nootropic and psychostimulatory effects confirmed by many clinical studies.
CDP-choline (cytidyl-5'-diphospholine, citicoline) is a compound naturally occurring in the body, built mainly of cytidine and choline. It participates in the biosynthesis and repair of cell membranes, biosynthesis of proteins, nucleic acids and acetylcholine neurotransmitters.
Following the discovery of the natural presence and importance of CDP-choline in the body, the compound started to be synthesized. Until now, the positive effect of the substance on the functioning of the brain has been confirmed by numerous tests and thus it has been registered as a medicine.
CDP-choline – the precursor to phosphatidylcholine
CDP-choline is a natural precursor to phosphatidylcholine, a compound that is the main building block of phospholipids of cell membranes, including cell membranes of neurons.
In the body, CDP-choline is hydrolyzed to choline, which is part of the phosphatidylcholine and cytidine molecule. Cytidine is transformed into uridine, which in the course of further biochemical transformations is transformed into cytidyl triphosphate (CTP), which is a key cofactor in the synthesis of phosphatidylcholine.
Through its participation in the synthesis of phosphatidylcholine, CDP-choline stabilizes and improves the function of cell membranes and their components, including membrane receptors. This is extremely important with regards to proper neurotransmission and neuroprotection.
CDP-choline – the precursor to acetylcholine
Supplied by citicoline, choline is transformed with the participation of choline acetyltransferase into acetylcholine – the neurotransmitter of the cholinergic and (partially) sympathetic systems. The cholinergic system is involved in the formation of the so-called memory engrams, as well as in cognitive functions and plasticity of the brain.
Optimal amounts of acetylcholine, as the sole neurotransmitter of the cholinergic system, are necessary for the proper functioning of the brain. When maintained at an appropriate level, CDP-choline effectively improves cognitive functions, ability to remember, learn and concentrate, also in case of age-related deterioration of cognitive functions, and increases the level of energy and motivation.
Application in diseases of the nervous system
As already mentioned, citicoline is registered as a medicine, which proves the high effectiveness of this compound. It accelerates returning to mental efficiency and motor functioning after stroke, improves cognitive functions accompanying dementia syndromes, as well as it positively affects memory and concentration in case of alcohol withdrawal syndrome and in elderly people.
In summary, Apollo's Hegemony CDP Choline is a high-quality preparation containing a thoroughly tested and effective substance, supporting the efficient work of the brain. The product is recommended primarily for people performing intensive mental effort, to improve intellectual performance, and as an aid supporting concentration and assimilation of information and to improve cognitive functions in older people.
CDP-choline exhibits synergism of nootropic action with compounds belonging to the racetam group.
Due to its nootropic properties, the product is recommended for use especially before intense intellectual effort.
CDP-choline enhances the L-dopa’s effect.
Apollo’s Hegemony is a manufacturer of dietary supplements whose composition is based on the latest scientific research and experience. The company is constantly expanding its range of products and taking care that they are of top quality.
It offers formulations which have multiple effects on the body and those with more targeted effects – e.g. boosting alertness and focus, increasing the tolerance to stress, promoting peaceful sleep and maintaining the health of the liver and adrenal glands.
Dietary supplements by Apollo’s Hegemony are effective owing to carefully selected composition which comprises the most potent forms and their precise doses. What is more, herbal supplements contain standardised extracts.
All products of this brand comply with good manufacturing practices (GMP) and their ingredients are vegan and vegetarian friendly.
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|per 1 capsule||amount||%DV|
|CDP-choline (Cytidine 5’- Diphosphocholine)||300 mg||*|
Microcrystalline cellulose, rice flour, hypromellose (capsule shell).
The product has not been tested for substances banned by the World Anti-Doping Agency (WADA).
CDP-choline (Citicoline), otherwise known as cytidine 5’-diphosphocholine, is a compound with nootropic properties discovered in 1950s which crosses very easily the blood-brain barrier.
After getting into the body, CDP-choline is broken down into choline and cytidine with a positive impact on the function of the nervous system. Cytidine is converted in turn into uridine – a component of nucleic acids which helps maintain normal mental performance. Choline is in turn a very important substrate for acetylcholine production and thus increases focus and mental clarity.
Despite of its great efficacy in penetrating the blood-brain barrier, CDP-choline boosts choline levels in the brain less effectively than alpha-GPC. This is due to the fact that a citicoline molecule provides smaller amounts of choline (about 18.5%). In comparison with choline bitartrate, CDP-choline has much higher bioavailability (even more than 95%). Citicoline also prevails over it due to the content of cytidine which is a precursor to uridine.
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