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Olimp Labs HepaPlus Sport Edition is a dietary supplement which is a new version of the preparation HepaPlus, designed for sportsmen and physically active people. The product contains a set of B-group vitamins, high-quality artichoke extracts and L-ornithine. The preparation supports proper functioning of the digestive system, especially liver.
People who practice sports, especially those who build strength and muscle mass should especially take care of liver health. Higher calorie needs and higher energy density of meals increases the burden of the digestive system and stimulates the work of the liver and the pancreas. Liver is an organ which plays as many as 500 important functions, out of which one of the main ones is the organism’s detoxification and elimination of harmful metabolic products, i.a. transformation of ammonia into urea in the ornithine cycle.
L-ornithine - is a non-protein amino acid, functioning as a carrier of carbon atoms and nitrogen in the urea cycle, the process taking place in the liver. Urea cycle is a kind of method of “dealing” of the organism with protein, which is built of amino acids providing the organism with nitrogen. The excess of nitrogen in the form of toxic ammonia needs to be excreted from the organism.
The core of the urea cycle is therefore detoxification of the organism from harmful nitrogen transformations. Ammonia is transformed with the participation of carbon dioxide in carbamoyl phosphate, the carbamoyl group of which is transported to ornithine with the simultaneous production of citrulline. Next, arginine is produced, which is a direct precursor of urea. Urea occurs with the simultaneous regeneration of ornithine, which may be again used in the urea cycle.
Artichoke (Cynara scolymus) is a plant demonstrating positive influence on the liver. It is the source of many active substances, primarily cynarine, caffeic acid and chlorogenic acid. The most important compound that influences the liver is cynarine - phenolic glycoside with clinically proven pharmacological cholagogic, cholepoietic and hypolipidemic effect by the influence on lipid metabolism. Cynarine stimulates regeneration of the liver’s flesh and demonstrates hepatoprotective properties, i.a. in poisonings with alcohol and carbon disulfide.
Artichoke has regenerative and detoxicating influence on the liver. Its preparations demonstrate the activity decreasing the level of cholesterol and triacylglycerols in blood, supporting at the same time the health of the cardiovascular system. Caffeic and chlorogenic acids present in artichoke have antioxidant, anti-inflammatory and anti-free radical effect.
B-group vitamins - thiamine, riboflavin, niacin, pantothenic acid and vitamin B6 - influence proper functioning of the nervous system and condition proper transformations of homocysteine and protect from its cumulation in the plasma, supporting at the same time the heath of the cardiovascular system.
Thiamine (vitamin B1) in the coenzymatic form, it takes part in the transformations of proteins, carbohydrates and lipids. It influences the functioning of internal secretion glands and takes part in the processes of production of nervous stimuli in peripheral nerves. One of the implications for the application of vitamin B1 is liver function disorder.
Riboflavin (vitamin B2) takes part in the processes of oxidation and reduction, which are important from the point of view of detoxification processes carried out by the liver. Vitamin B2 influences proper functioning of the eyesight, conditioning transparency of eye tissues. Riboflavin is essential for the transformations of vitamin B6 to its active coenzymatic form and for the synthesis of niacin from tryptophan. Deficiency of this vitamin leads to numerous metabolic disorders and skin lesions.
Niacin (vitamin B3), being the component of NAD and NADP, it creates enzymes from the class of oxidoreductases - dehydrogenases, which take part in the metabolism of proteins, carbohydrates and lipids and in the synthesis of i.a. thyroxine and sex hormones. Niacin has properties decreasing the level of total cholesterol and triglycerides and the properties widening blood vessels.
Pantothenic acid (vitamin B5) forms coenzyme A (CoA), which is a carrier of acetyl groups, essential in many processes taking place in the organism. It demonstrates positive influence on the state of skin, contributing to maintaining its elasticity and improves the structure of epidermis. Vitamin B5 deficiencies may lead to disorders of the functioning of the digestive and nervous system and disorders of the function of adrenal glands.
Vitamin B6 plays an important role in the synthesis of neurotransmitters, regulates energy transformations i.a. by the participation in the processes of gluconeogenesis and glycogenolysis. It takes part in the creation of hemoglobin and decreases the level of homocysteine, having protective influence on the cardiovascular system. By taking part in the transformations of lipids and fatty acids being the components of mucous membranes, vitamin B6 supports optimal regeneration of liver cells.
To sum up, Olimp Labs HepaPlus Sport Edition is a complex preparation, supporting proper work of the liver on many layers. The product is recommended to sportsmen, people taking care of health and in order to support regeneration of this organ in high-protein and high-calorie diet, alcohol abuse and as prophylaxis.
Current lifestyle requires a lot of effort from the liver. The best effects will be achieved when we introduced changes to our eating habits in comparison to preparations supporting liver work. Quitting alcohol, refined sugar, highly-processed food and stopping the intake of analgesics without a serious reason (especially paracetamol) is an important step on the way to a healthy liver and prophylaxis of disorders of this organ.
Olimp is a Polish company offering dietary supplements and supplements for athletes that are made of carefully selected and safe for health ingredients. Among the products of this brand are protein supplements, amino acid supplements, pre-workout supplements and creatine. The company also allows the purchase of supplements inducing a strong muscle pump by raising significantly the level of nitric oxide in the blood and supplements restoring acid-alkine balance. Also noteworthy are supplements helping to reduce body fat, regulating metabolism and improving of the hair, skin and nails.
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|per portion (1 capsule)||amount||%DV|
|Artichoke extract (Cynara scolymus L.) standardised to 5% cinarine||350 mg||-|
|L-ornithine aspartate||100 mg||-|
|including L-Ornithine||50 mg||-|
|Thiamin (thiamin hydrochloride)||0.55 mg||50%|
|Riboflavin (vit. B2)||0.7 mg||50%|
|Niacin (nicotinic acid amide)||8 mg||50%|
|Pantothenic acid (calcium D-pantothenate)||3 mg||50%|
|Vitamin B6 (pyridoxine hydrochloride)||0.7 mg||50%|
Microcrystalline cellulose, magnesium salts of fatty acids, capsule (gelatin, E 171).
Artichoke extract - an extract of Mediterranean perennial, which is a rich source of active compounds, such as chlorogenic acid (eg. cynarine), sesquiterpenes (eg. cynaropicrin), flavonoids and glycosides. Artichoke extract is widely used in medicine: a shielding action for liver, stabilizing cell membranes, is antioxidant, inhibiting oxidation of LDL cholesterol (the so-called bad cholesterol). In the etching process, not only protects the gastrointestinal tract itself, but by increasing the secretion of digestive juices, beneficial effect on the assimilation of nutrients. It has a soothing effect on the digestive system. It has a slight potential diuretic.
Extract of artichoke is an extract used in health-enhancing supplements, supporting digestion, protecting the liver and lowering LDL cholesterol. It is often combined with other plant extracts, and aspartate-I-ornithine.
Dosage: 600-1000 mg per day.
L-aspartate L-ornithine (salt of the amino acids L-ornithine and L-aspartic acid), which is involved in the detoxification of ammonia and affecting regeneration of liver cells. L-aspartic acid is involved directly or synthetics in assisting in the physiological processes: energy conversion, synthesis of purines and urea enhances the synthesis of nitric oxide. L-ornithine, endogenous non-protein amino acid which is a precursor of arginine. Mediates in the metabolic cycle of urea synthesis from ammonia and nitrogen excretion. It is a citrulline acceptor. Synthesizes polyamines regenerating the liver. Part of the preparations for health, used in supplementation in the form of no-boosters. Available at the www.muscle-zone.pl
Dosage: varied from a few dozen mg to a few g / 24h
Ornithine belongs to endogenous non-protein amino acids, it is produced by transformation of the amino acid arginine and glutamic acid. It is an intermediate in a metabolic cycle urea synthesis from ammonia and carbon dioxide. The degradation of amino acids in the liver making the first removes nitrogen (alpha amino groups are transferred to alpha-ketoglutarate) and leads to the formation of glutamate, transformed into the form of ammonium ions. It is necessary to neutralize the highly toxic ammonia, which is carried out by aspartate, creating argininosuccinate. A further phase of change is the formation of arginine and fumarate. Then the cycle is repeated. In the transition process, ornithine is the starting material for the enzyme that catalyses a particular stage of the urea synthesis. It is also an acceptor for the synthesis of citrulline. Ornithine, through the synthesis of polyamines, has a regenerating effect on the liver.
Ornithine is available as mono-preparation (often included with the other ingredients of supporting liver function) and multi-component supplements containing ornithine aspartate. Indispensable in sports supplementation in no-boosters (pre-workout products) as it stores the arginine, it slows down its expenditure and allows for more effective use in the synthesis of nitric oxide. Available in the full range at: www.muscle-zone.pl
Dosage: There are no specific standards for daily consumption. 200 - 1500 mg / 24h, commonly used in supplementation.
Vitamin B1 (thiamin, vitamin B) improves mental alertness and strengthens the nervous system ensuring the proper functioning of the brain. It improves cardiac and muscular system. It is suportive in the treatment of shingles. Involved in the metabolism of carbohydrates and fats. Natural source of vitamin B1 are brown bread, yeast, eggs, raw vegetables, meat, milk, legumes, cheese.
Vitamin B1 deficiency hinders the processes of decomposition of sugars (catabolism), causes a loss of appetite and disorders in the functioning of the digestive tract, can cause polyneuritis and disease beriberi.
Dosage: Recommended daily intake is 1-2 mg.
Thiamine hydrochloride - a highly bioavailable form of thiamine, also called vitamin B1. Due to an important role that it plays in carbohydrate metabolism, its increased supply is recommended to people with excessively high concentration of sugar in blood. It facilitates their processing in the organism and supports the activities that aim at restoring optimal glycemia. An important role in the metabolism of nutrients is also played by an integral component of carboxylase coenzyme - thiamine pyrophosphate.
Some source suggest the effectiveness of thiamine in relation to the health of the cardiovascular system, apart from decreasing glucose level in blood, it is also reflected in optimization of blood pressure. Although this aspect of effectiveness of vitamin B1 requires further research, it is another argument demonstrating special needs of taking care of proper thiamine supply by people from the risk group of the circulatory system diseases.
Among people who are especially prone to vitamin B1 deficiencies there are also people fighting with excess weight and frequently drinking alcohol.
Vitamin B2 (riboflavin) is soluble in liquids, is involved in the metabolism of proteins, fats and carbohydrates. Required for growth of the organism. Takes part in the production of erythrocytes (red blood cells). It is located in natural foods, such as yeast, meat (especially liver, kidney, heart), milk, fish and green leafy vegetables.
A deficiency of vitamin B2 inhibits the growth, diseases of the mouth, loss and greasy hair, seborrhea and stratification of nails. Increases skin roughness and susceptibility to acne and oily skin.
Dosage: 1-2 mg per day.
Vitamin B3 (vitamin PP, niacin, nicotinic acid, nicotinamide) is niacinamide niacin. It is used in interaction with vitamins B1, B2 and B6 in the synthesis of hormones during lactation. It provides proper functioning of the brain and nervous system. It is helpful in inflammatory conditions of the skin. Required for synthesis of sex hormone, estrogen, testosterone, cortisone, and insulin. It does not lose its properties in the manufacturing and storage. The source of acquiring vitamins PP are both products of animal origin (the lean meat, eggs, fish) and vegetable origin (dates, figs, hazelnuts, plums).
Dosage: 2-12 mg / day for children, 14 mg / day for women, 16 mg / day for men and 17-18 mg / day for pregnant or nursing women.
Nicotinic acid amide – also known as nicotinamide, belongs to a group of compounds referred to as vitamin B3, along with nicotinic acid and inositol hexanicotinate. It exerts its main biological activity as a precursor to two key coenzymes for efficient energy metabolism of the body: nicotinamide adenine dinucletodide and nicotinamide adenine dinucleotide phosphate. They are responsible for carrying hydrogen and electrons in the respiratory chain and thus facilitate efficient energy production by the human body.
Nicotinamide supplementation is recommended for active persons not only because of its ability to promote the body’s energy efficiency. It has also a beneficial impact on mind, increases tolerance to stressors and may reduce symptoms of depression. It is pointed out that niacin supplementation correlates positively with sleep quality.
Unlike nicotinic acid, nicotinamide does not show the ability to produce a “flush effect”, namely redness in the face caused by taking large doses of niacin. It has been also shown to influence partly cardiovascular function.
Nicotinamide is also indicated to influence beneficially the absorption of other B vitamins and vitamin D. This compound should be taken with caution by diabetics because it can increase the body’s demand for insulin.
Vitamin B5 (calcium pantothenate, pantothenic acid, pantotenol) is part of a complex of B vitamins affects the development of the central nervous system, is the building substance of cells. In the body synthesized by the intestinal bacteria. It occurs in animal products (meat, kidneys, liver) and plants (wheat germ, wheat bran, nuts, grains, green vegetables). Prevents fatigue and excessive stress, accelerates the healing of cuts and wounds, acts as a stimulant for the side effects of the use of antibiotics. Deficiency causes skin changes, and difficulty in blood clotting.
Calcium (element chem. symbol Ca, atomic no. 20, the group of alkaline earth metals) is the basic building substance of bones and teeth, in which stored is 99% of the element, in the form of hydroxylapatite. When building bones and teeth, phosphorus is very important in the right proportion. It is a base-forming element and activator of many enzymes (ATPase) necessary to release the energy of ATP. It has a significant effect on blood clotting and regulates blood pressure and neuromuscular conductivity. Thanks to the reduced permeability of cell membranes, it soothes the symptoms of food allergies. Calcium is actively involved in the metabolism of iron interacts with vitamins A, C and D and phosphorus, magnesium. Natural source of calcium are animal products (dairy products, sardines, salmon, sprats eaten with bones) and plant products (nuts, soybeans, sunflower seeds). Absorption takes place in the small intestine (less in the colon), it has an effect on the level of lactose, insoluble fibre, organic acids, alkalinity (low pH). The best absorption have organic compounds (lactates, amino acid chelates etc.). Obstructing the absorption of calcium is caused by: phytic acid and oxalic acid as well as excess fat. Scientific studies have confirmed that the combination of calcium, magnesium, boron and vitamin D in dose 3 mg / 24h effectively prevent osteoporosis. Supplements on the market are both mono-preparation supplements (enriched with vitamin D3) and multi-component supplements, available at www.muscle-zone.pl.
Calcium deficiency disorders manifested in the construction of the bones (osteoporosis) and iron metabolism. The symptoms are: rickets, cramps and muscle tremor, osteoporosis.
Excess resulting from an overdose of calcium supplements containing vitamin D3 for children and adults overdose of calcium (hypercalcemia). Symptoms of hypercalcemia are: lack of appetite, vomiting and constipation.
The dosage administered in various publications are inconsistent: 800 - 1000 mg / 24 h (100 - 500 mg / 24h)
Vitamin B6 (pyridoxine, pyridoxal, pyridoxamine) is soluble in the liquid. It participates in the metabolism of proteins, fats and carbohydrates. By reducing the amount of fat in the blood do not enable deposition of the body. It helps the absorption of magnesium and vitamin B12 (cobalamin). It works on the muscle antispasmodic and anti-inflammatory pain in the joints. It acts anti. It provides efficient operation of the brain. It increases energy increasing vigor of a man. The demand for vitamin B6 increases during pregnancy and breast-feeding infants. The natural product is: yeast, eggs, wheat germ, meat (liver), wheat bran, nuts, peanuts peanuts, soybeans. There is a hypothesis that can be synthesized by intestinal bacteria.
Deficiency of vitamin B6 causes abnormal metabolism of proteins, decrease in lymphocytes in the blood, causes a feeling of lethargy and fatigue intensifies.
Dosage: 1.5-2.5 mg daily (increased demand during pregnancy and lactation).
What is pyridoxine hydrochloride?
Pyridoxine hydrochloride is a basic, the most commonly used form of vitamin B6 in supplements and fortified foods. It is a vitamin soluble in water. It converts to the active form of the vitamin - pyridoxal phosphate.
Vitamin B6 is a cofactor in many enzymatic reactions. It takes part in the production of many neurotransmitters, such as GABA, serotonin and catecholamines and it takes part in the metabolism of amino acids, carbohydrates and lipids. It is an important factor for the process of the creation of red cells and hemoglobin and its deficit may be one of the factors causing anemia. This vitamin contributes to maintaining proper energy metabolism and is important for maintaining well-being and good psychological condition. Its presence supports the breakdown of pro-inflammatory homocysteine to cysteine and further metabolites, thanks to which it may decrease the risk of atherosclerosis and cardiological incidents.
Pyridoxine hydrochloride may be found in many vitamin B complexes and vitamin-mineral preparations available in the offer of muscle-zone.pl.
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