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Swanson Sulforaphane is a dietary supplement that includes BroccoPhane® - a highly concentrated, patented broccoli seed extract. It is standardized for sulforaphane content recognized as a key factor responsible for health-related properties attributed to cruciferous vegetables.
The preparation improves detoxification of the body, preventing the mutation of DNA and helps to remove pathogenic microorganisms from the body. It favors strengthening of health condition and can reduce the risk of developing many diseases, including cancers.
Sulforaphane is an organic chemical compound that belongs to the isothiocyanate group. According to the researchers, due to its biological action and multidirectional activity in a human body, sulforaphane supplementation may be used in the prevention and therapy of many serious diseases. Sulforaphane is attributed with, among others, anticancer, antioxidant, anti-inflammatory and antibacterial properties.
Unfortunately, it is very difficult to obtain sulforaphane from natural sources. Glucoraphanin present in cruciferous vegetables is the precursor for the production of sulforaphane, whose large amounts are deposited in broccoli seeds and sprouts. The process of converting glucoraphanin to biologically active sulforaphane requires the presence of a specific enzyme - myrosinase. It is very sensitive e.g. to high temperature, which is why the heat treatment of fresh broccoli makes the production of an active sulforaphane practically impossible. In practice, this means that glucoraphanin enters the body in an intact form. It may be partially hydrolyzed by the microflora present in the large intestine, but the amount of sulforaphane obtained is not sufficient to carry therapeutic significance.
The BroccoPhane® contained in the supplement was prepared in such a way as to provide a large amount of ready-made, active sulforaphane. As a result, users can benefit from all of its properties in the body.
Effective detoxification of the system
Sulforaphane is a very effective activator of enzymes responsible for detoxification of the body. It strongly affects especially the enzymes of the I and II detoxification phase. Thus, it improves the metabolism and elimination of potentially mutagenic and genotoxic compounds from the body, and indirectly may also reduce their reactivity.
This action carries many benefits to a liver, which is relieved in its work. In addition, as the research shows, sulforaphane protects hepatocytes and prevents them from being damaged by various pharmaceuticals, alcohol, preservatives added to food, etc. It can also contribute to an increase in the concentration of a preventive glutathione.
The mechanism described above, related to the regulation of the expression of enzymes of the I and II detoxification phase, is essential for the prevention of pathological carcinogenesis. Mutagenic and genotoxic compounds must be eliminated from the body before they damage DNA and initiate the process of carcinogenesis. Due to the presence of sulforaphane, this process is quick and efficient.
What's more, sulforaphane can also directly affect the process of carcinogenesis and change the course of it. Studies have shown that this compound is a potent blocker of the cell cycle and an inducer of apoptosis of ill-formed cells. In addition, it promotes the suppression of tumor cell proliferation and limits the expansion of those genetically modified.
Sulforaphane has strong antimicrobial properties and helps to eliminate pathogenic microorganisms from the body. It is recommended especially for people infected with Helicobacter pylori, which contributes to the formation of stomach ulcers, and in extreme cases may even lead to the development of gastric cancer.
The researchers have yet not identified the mechanism that is responsible for these properties, but both in vitro and in vivo studies showed that already 5-day administration of sulforaphane was sufficient to make eight out of eleven H. pylori strains leave the body. It seems that sulforaphane not only promotes the elimination of bacteria from the body, but it also strengthens the stomach mucosa, which prevents its colonization by H. pylori.
Sulforaphane helps to reduce the intensity of inflammation in the body. It works well in the prevention of diseases induced by chronic inflammation, it can be also helpful in some autoimmune diseases, in the course of which there is an exacerbation of inflammation.
Researchers believe that sulforaphane directly affects the activity of the NF-kβ transcription factor. As a result, the expression of iNOS and COX-2 enzymes and the reduction of TNF-α cytokine production occur. Sulforaphane can probably also affect macrophages and inhibit the release of HMGB1 protein. This protein strongly promotes the processes involved in the inflammatory reaction, which in turn causes the intensity of inflammation.
In summary, Swanson Sulforaphane is a supplement that allows you to take a full advantage of the sulforaphane potential. It is recommended especially to people who are exposed to constant contact with toxins, i.e. people living in large cities, people addicted to nicotine or abusing pharmacological agents (e.g. painkillers), as well as individuals consuming processed food.
The supplement contains a highly concentrated broccoli sprout extract, standardized for the sulforaphane content. To achieve the desired effects, 1 capsule a day is sufficient. Sulforaphane and its metabolites are easily removed from the body in urine, which is why overdosing is rather unlikely. Higher doses do not seem to bring better results.
SWANSON is a well known company operating since 1969, which offers a wide selection of diet and nutritional supplements. Among their products are antioxidants, amino acid supplements, products improving immunity, probiotics, minerals and vitamins. At SWANSON you can also purchase of supplements enhancing your cardiovascular stamina, urinary, nervous and digestive systems. The offer includes products designed specifically for women or men, as well as supplements helping to loose weight.
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|per 1 capsule||amount||%DV|
|Sulforaphane (from BroccoPhane® 20-1 broccoli sprout concentrate standardized to 0.4% sulforaphane)||400 mcg||*|
Rice flour, hypromellose (vegetable capsule), may contain one or both of the following: magnesium stearate, silica.
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