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Aliness Milk thistle seed extract 190 mg + artichoke is a unique blend of two standardized plant extracts known for their beneficial effects on the liver. The supplement is available in the form of vegetable capsules; it can be used by people who prefer a vegetarian or vegan diet.
Milk thistle (Silybum marianum) is a valued medicinal plant. It is the fruits (often referred to as seeds) of the plant that are used as a raw material. They contain a unique phytocomplex (the so-called silymarin), which is composed of pharmacologically active substances. Its composition is dominated by silibinin (50-60%), considered the most active compound, as well as isosilibin (5%), sylichristine (20%) and silidianine (15%).
The mechanism of action of silymarin is complex. By changing the structure and sealing the cell membrane of hepatocytes, it limits the entry of various toxic substances into their interior, and also protects hepatocytes from apoptosis. Moreover, it shows a beneficial effect on the activity of dismutase and peroxidase enzymes and glutathione levels. Thanks to this, it protects the liver against the harmful effects of free radicals. Silibinin has been also proven to stimulate liver regeneration.
Silymarin, in addition to its effect within the liver, may also affect glycemia. It not only helps to lower blood triglyceride levels but also to increase cellular insulin sensitivity and promote the reconstruction of pancreatic beta cells. It can potentially be used in the prevention of diabetes.
Artichoke (Cynara scolymus) is a tasty and nutritious edible plant, which is also used for medicinal purposes. For therapeutic purposes, the leaves growing at the base of the plant are used, because they contain the most biologically active substances, such as cynarine or chlorogenic acid.
Artichoke extract has a beneficial effect on the digestive system, liver, and bile ducts. It shows biligenic and choleretic effects, promotes hepatic parenchyma regeneration and protects against fatty liver. It can also be used to support digestion and to regulate the rhythm of bowel movements.
To sum up, Aliness Milk Thistle Extract 190 mg + Artichoke is a preparation that comprehensively supports liver health. It is especially recommended for people who do not care about proper nutrition, often reach for stimulants or pharmaceuticals.
The preparation is based on ingredients of plant origin, which determines its safety, even after prolonged use. The product is suitable for vegans and vegetarians. The product can be also used to support the liver burdened by poor diet, alcohol, stimulants, pharmacological substances (e.g. painkillers).
There is evidence that milk thistle can exert an inhibitory or inductive effect on cytochrome P450 (CYP-450) 1A2, 2C19, 2D6, 2E1, 3A4, as well as P-glycoprotein. Therefore, people taking drugs metabolized by these enzymes should consult a specialist before implementing the product.
Aliness is a Polish brand owned by Medicaline. The company has advanced development and research facilities and meets the demanding European Standards of Production and Storage based on the pharmaceutical standard GMP and HACCP. A team of experienced specialists supervises the quality of manufactured dietary supplements. The company uses only the highest quality certified raw materials, often occurring in patented forms.
Aliness cooperates with the research laboratories accredited by the Main Pharmaceutical Inspectorate - SGS Poland and J.S. Hamilton Poland S.A., and also with the National Institute of Medicines, responsible for quality and safety control in research and development. Many Aliness products have an ecological certificate, which is a guarantee of the lack of use of artificial fertilizers, pesticides and chemical plant protection products at all stages of the production of the raw material.
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Capsule shell (binding agent: hydroxypropyl methylcellulose).
Extract from milk thistle (Silybum marianum) a plant of the Asteraceae family, of which a source of active substances are fruit, providing silymarin (silibilina, silydianina, silichrystyna in the ratio of 2: 1: 1), an antioxidant, natural protection of liver cells, affecting positively the level of glutathione, anti-inflammatory properties (slow release of prostaglandins, and histamine). It affects the blood lipid profile by lowering levels of LDL cholesterol. It is used in medical prophylaxis and treatments (food poisoning, liver disease and in case of high calorie diet). Available in the form of mono-preparation supplements and multicomponent supplements supporting the work of the digestive system and the liver in the "health."category. Preparations available at www.muscle-zone.pl
Dosage: Dose converted into silymarin, from 200 to 400 mg / 24h
Artichoke extract - an extract of Mediterranean perennial, which is a rich source of active compounds, such as chlorogenic acid (eg. cynarine), sesquiterpenes (eg. cynaropicrin), flavonoids and glycosides. Artichoke extract is widely used in medicine: a shielding action for liver, stabilizing cell membranes, is antioxidant, inhibiting oxidation of LDL cholesterol (the so-called bad cholesterol). In the etching process, not only protects the gastrointestinal tract itself, but by increasing the secretion of digestive juices, beneficial effect on the assimilation of nutrients. It has a soothing effect on the digestive system. It has a slight potential diuretic.
Extract of artichoke is an extract used in health-enhancing supplements, supporting digestion, protecting the liver and lowering LDL cholesterol. It is often combined with other plant extracts, and aspartate-I-ornithine.
Dosage: 600-1000 mg per day.
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