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Life Extension Mega EPA/DHA is a dietary supplement in the composition of which there is an ideally balanced, appropriately high dose of omega-3 fatty acids: EPA (720 mg) and DHA (480 mg). They have been isolated from the highest-quality fish oil subjected to molecular distillation. It is the only technological process, which guarantees 100% effectiveness in removing metals, PCB and other toxic substances. Thanks to this, the final product is characterized by the highest purity, is non-toxic and is safe for the organism.
The preparation is recommended as general health prophylaxis. EPA and DHA play a range of important functions in the organism: they are precursors of vital bioactive mediators, are responsible for the proper functioning of the nervous system, influence the work of heart and protect against circulatory diseases. They are essential to maintain optimal body condition and mental efficiency.
EPA and DHA, i.e. eicosapentaenoic and docosahexaenoic acids are organic compounds from the group of unsaturated essential fatty acids (EFAs). Specific chemical structure gave it the name of long chain fatty acids of omega-3 type. EPA plays in the organism the role of DHA precursor, however, the synthesized amounts are too small in order to fully satisfy the needs of the organism.
EPA and DHA have an important influence on health and proper functions of the organism. DHA mainly fulfills building functions – it is in the composition of phospholipids, cell membranes and conducts intercellular metabolic processes. It constitutes a considerable part of acids present in the brain and eye retina and its high amounts are stored in the heart. EPA is primarily responsible for the production of eicosanoids – tissue hormones, which regulate the growth of cells, muscle activity, coagulation processes and synthesis of various hormones and neurotransmitters.
EPA/DHA for the cardiovascular system
In numerous scientific studies it has been proven that there is a strict correlation between the intake of omega-3 acids and the risk of developing heart and circulatory diseases. It is assumed that omega-3 acids may decrease mortality in patients after myocardial infarction and lower the risk of sudden cardiac death.
Enriching a diet with omega-3 acids positively influences lipid profile. It lowers the concentration of triglycerides and unbeneficial cholesterol fraction LDL and simultaneously it leads to the increase of “good” HDL cholesterol level. By the same token, the risk of developing atherosclerosis becomes minimized.
EPA and DHA acids have anticoagulant properties. They inhibit the aggregation (agglutination) of platelets, accelerate fibrin breakdown and consequently prevent the creation of dangerous clots and embolisms.
Omega-3 fatty acids protect against heart rhythm disturbances. They affect subentities creating sodium and calcium ion channels, leading to the decreased activity of cells building heart muscle (cardiomyocytes). Thanks to this, the amount of abnormal and irregular heart contractions is limited.
Omega-3 acids positively modulate blood pressure. They change the composition of fatty acids in cell membranes and the amount of ATP resealed from the cells of vessel endothelium and also they lower the concentration of noradrenaline in the plasma. All these factors prevent the excessive increase of pressure.
EPA/DHA for the nervous system
It has been proven in numerous experimental and clinical studies that omega-3 acids are essential for neurological health and mental well-being. While DHA is responsible mainly for maintaining proper brain structure, EPA primarily influences mood.
DHA stimulates growth and development of neurons. It makes nerve cells more branched and elastic, thanks to which they may better fulfill the assigned functions. As a building block and cell membrane modulator, DHA is responsible for proper cell signaling. Such activity is reflected in mental ability – good memory, logical thinking, pace of processing information and the ability to associate facts.
Researchers claim that there is a strict relationship between depression and insufficient amount of EPA in a diet. It has been proven in many randomized, placebo-controlled studies that supplementing a diet of patients suffering from depression with omega-3 fatty acids and especially EPA, contributed to alleviating the symptoms of the disease and limited the frequency of depression episodes.
Both DHA and EPA protect against the drop in cognitive functions and lower the risk of the development of neurodegenerative diseases. People with low level of DHA and EPA in hippocampus neurons performed much worse in cognitive tests and were more often diagnosed with Alzheimer’s disease. Supplementing the diet with omega-3 acids, on the other hand, was reflected in the improvement of memory and better cognitive functions in all subjects.
EPA/DHA in the prophylaxis of civilization diseases
Omega 3 fatty acids may prevent various civilization diseases, especially induced by the harmful influence of free radicals and chronic inflammations. They reduce oxidative stress and protect cells against damages caused by the activity of reactive oxygen forms. Eicosanoids from EPA (prostaglandins, thromboxane and leukotrienes) regulate the course and intensity of inflammatory reactions in the organism.
Summing up, Mega EPA/DHA is the best way to supplement diet with unsaturated essential fatty acids. It allows to maintain health and mental efficiency at all ages and protects against the risk of atherosclerosis and cardiovascular diseases. It is especially recommended to pregnant women, seniors and sportsmen who expose their organisms to excessive physical effort.
International health organizations recommend prophylactic intake of EPA and DHA at the level of min. 500 mg a day. Because of the high content of omega-3 in the supplement, 1 to 3 capsules a day suffice in order to achieve the desired effect.
For maximal absorption of active substances in the supplement, it is worth taking the preparation with a meal containing a source of fat.
It should be borne in mind that omega-6 fatty acids are a kind of competition for omega-3 acids. Because of this, the supplementation should not be combined with a meal providing large amounts of omega-6 fatty acids (e.g. from vegetable oils).
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highly refined fish oil concentrate (Alaska Pollock), gelatin, glycerin, purified water, carmel color, natural flavor, mixed tocopherols, rosemary extract, sunflower oil
Calories are the conventional name of the unit expressing the energy value of food, the demand and energy expenditure in human body, which in fact is 1 kilocalorie (1 kcal). 1 kilocalorie is the amount of thermal energy required to heat 1 g of water and 1 degree Celsius. The SI unit of thermal energy is 1 joule (1J), equal to approximately 4,185 kcal.
The energy value is determined by the chemical composition of the food product, by means of the so-called. physiological equivalents. Most often Atwater equivalent is used: ratio for protein 4 kcal / g, for carbohydrates 4kcal / g, and for fat - 9kcal / g.
The energy value carried out with the so-called. "Caloric bomb" is equivalent to the physical energy, amounting to 4.1 kcal per 1 g carbohydrate to 5.65 kcal per 1 g protein, 9.45 kcal per 1 g of fat.
Nutritional value, determines the suitability of a food product for realizing life functions of human, the higher it is - the higher bioavailability and lower quantity for consumption for obtaining the effects.
Fat is an essential nutrient plant and animal organisms. Because of the nutritional value and composition of fats are divided into: saturated (mono-saturated and multi-saturated fatty acids) and unsaturated fatty acids (including essential fatty acids - EFA). The group of lipids include lipids (triacylglycerols, waxes), complex fats (glycolipids, phospholipids), sterols and isoprenoids. Saturated fatty acids is a group of fatty acids having different carbon chain lengths, in which except for the carboxyl group, each of the carbon atoms is bound by a single bond. May adversely affect the lipid profile, so they can be used in limited quantities. Fats are a concentrated source of energy, with different flavours, facilitating the consumption and swallowing of food. They have building functions (part of cell membranes and co-create the white matter of the brain). EFAs are precursors of tissue hormones and biologically active compounds. The unsaturated fatty acids include fatty acids from the group Omega-3, Omega-6 and Omega-9 (the last digit indicates, on which, counting of the end of the chain, there is a double bond in the appropriate carbon chain. The essential fatty acids include: acids, medium-Omega-3 [n-3 ] included in EFAs [essential fatty acids], and long chain (eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA]) Omega-6 and Omega-9. the number indicates that the last double bond in the carbon chain is on the third from the end carbon atom. The acids from the omega 3 group are essential components of cell membranes, they are precursors of eicosanoids and biological activators. They must be combined with ingestion in suitable proportions of Omega-6 acids.
Dosage: Depending on demand and applied diet. It is generally accepted that fats should constitute 20-30% of the energy (calorie) of meals daily.
Vitamin E (tocopherol) is a fat soluble. Due to its antioxidant action, it is a protection of other vitamins (e.g. Vitamins A). Protects the body against free radicals, strengthens the walls of blood vessels and its capacity, causing their dilation and dissolution of blood clots. With the reduction of coagulation, it is used as an antiatherogenic medicine, it allows for the proper course of pregnancy. In cooperation with selenium it slows the ageing process of cells, strengthening connective tissue. In the food it is present in whole-grain bread, sprout and grains, vegetable oils (soybean, sunflower), soya beans and sunflower seeds, vegetable fat and hen egg yolks. Also it is used in sports medicine in the form of nutrients and supplements.
Vitamin E deficiency reduces building of red blood cells, results in changes in muscle and disorders of pregnancies.
Dosage: for children, 0.5 mg / 1 kg of weight; for adults 10-30 mg per day.
Fish oil is a source of long chain saturated fatty acids of the Omega-3 (EPA - eicosapentaenoic acid; DHA - docosahexaenoic acid), which are part of cell membranes and the precursor of eicosanoids, and an activator. When consuming acids Omega 3, it must be balanced with the Omega 6 (using in the range of from 1: 6 to 1: 1). Fats contained in fish oil help to reduce body fat, affect the oxygenation of the body, and the operation of systems: circulatory, respiratory, nervous system and the musculoskeletal system. Available in the form of mono-preparation supplement or as an ingredient of supplements in the category of "health and beauty".
EPA (eicosapentaenoic acid) – what is it?
EPA (eicosapentaenoic acid) is a long-chain, polyunsaturated omega-3 fatty acid. The chain of the fatty acid consists of 20 carbon molecules, and the first bound out of five double bounds is located at the third carbon from the omega end, which is characteristic for omega-3 acids. It is present in large quantities in fish oils, where it is accompanied by docosahexaenoic acid (DHA).
EPA is a precursor to prostaglandins and other eicosanoids, which contributes to the reduction in inflammations. It is involved in inhibition of platelets aggregation. It contributes also to the reduction in triglycerides level in blood. EPA block the activity of an enzyme, phospholipase A2, present on cell membranes, which under the influence of stressors can release polyunsaturated fatty acid (from the group of eicosanoids) into the glycerol skeleton. To some extent, EPA can be also converted into 22-carbon DHA. The both acids have positive impact on the condition of the nervous system and cardiovascular health.
Eicosapentaenoic acid contained in dietary supplements with omega-3, which are available in the offer of muscle-zone.pl
DHA (docosahexaenoic acid) - acid of omega-3 family, unsaturated fatty acids with the last double bond in the chain located on the third carbon atom from the end. Synthesized in the human body to eicosapentaenoic acid, or retrieved from foods of marine origin (fish, particularly salmon). In the medicine it is indicated for the treatment of depression, Alzheimer's ADHD. There has been its positive impact on the insulin metabolism noted as well as on endocrine and cardiovascular systems. When used in appropriate doses, it has a beneficial effect on the composition and appearance of the body. In the the supplementation it is part of formulas containing fish oil, which fill in the gaps of unsaturated fatty acids Omega 3, recommended for people with different physical activity.
Dosage: 200-2000 mg per day
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