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ProBiota HistaminX ProBiota HistaminX PRE-SALE 60 caps.
Seeking Health
26.74 $
Location: eu change

ProBiota HistaminX

All variants:

From 3 units only: 26.20 $ / Units. -2%

Shipping weight: 150g
No gluten

As an alternative, we recommend:

Bifidobacterium Balance 10 mld. 30 caps.
Bifidobacterium Balance 10 mld. 30 caps.
8.56 $
Compare composition
Old price: 29.19 $
Price for shipping in about 4 weeks:
26.74 $ With VAT
0.45 $ / serving
Additional thermal packaging + 1.72 $
  • Free from bacterial strains producing histamine 
  • Promotes effective management of histamine level
  • Helps to maintain proper level of DAO
  • Ideal for people with histamine intolerance
  • Supports proper intestinal microflora
  • Alleviates the symptoms of histamine intolerance
  • Improves the work of the digestive system
  • Facilitates histamine metabolism
  • Unique acid-resistant cells  
  • Reduces allergy symptoms
  • Tightens intestinal barrier
  • With an additive of a prebiotic
  • Improves immunity

Seeking Health ProBiota HistaminX is a unique probiotic complex designed for people who deal with hypersensitivity or intolerance of histamine. The preparation is conducive to improving immunity, regulates the immune response of the organism and facilitates the work of the digestive system. Moreover, it effectively alleviates the symptoms of allergy.

In the composition of the preparation there are carefully selected strains of probiotic bacteria, which are conducive to DAO production (an enzyme braking down histamine) and support the functioning of the intestinal barrier. The formula is free from strains, which are responsible for converting histidine in histamine and may deteriorate the problem in people sensitive to the presence of histamine.    

The effectiveness of the supplement is supported by a special system of encapsulation. Probiotic bacteria were closed in innovative acid-resistant capsules, which allow them to go through the unbeneficial environment of the stomach and safely reach the intestines, i.e. a target place of activity. 

Problematic histamine  
Histamine is an organic chemical compound classified to the group of tissue hormones, which in the human organism is synthesized from histidine. It plays a few important functions - i.a. it takes part in the transport of blood and supports the process of digestion. A fundamental role of histamine is the function of pro-inflammatory mediator. After the contact with an allergen, it is released from mast cells and cause a range of biochemical reactions, as a consequence of which the symptoms of allergy appear (rash, nasal secretion, hay fever, diarrheas and in extreme cases even problems with breathing or sudden drop of blood pressure).

Histamine is also present in food. Large amounts of histamine are contained in pickled products, some types of cheese and cocoa. It may be also encountered in processed food products, especially in “light” products, where fats are replaced by chemical compounds, which are a powerful source of histamine.

A central role in histamine metabolism is played by the enzyme DAO (diamine oxidase). The stimulus for its production is food, which contains a lot of histamine. DAO deficiency or the intake of large amounts of products which contain DAO inhibitors slow down the process of histamine elimination from the organism, which may cause the symptoms related to intolerance. A considerable role in the development of histamine intolerance is played by disorders of intestinal microflora. Researchers suggest here permeability of intenseness and SIBO.

Probiotics and histamine   
Probiotics may actively support the management of histamine level, however, not all strains of probiotic bacteria will be appropriate for people with hypersensitivity or intolerance of histamine. It should be borne in mind that some species inhabiting the intestines are responsible for transforming histidine into histamine, therefore strengthening their population may increase histamine production and intensify the problem of its intolerance.

The presented supplement contains very carefully selected probiotic bacteria strains. None of them are responsible for the production of histamine. The producer of the preparation focused on the strains, which tighten intestinal barrier and support the breakdown of biogenic amines (including also histamine).

Bifidobacterium infantis naturally occurs in oral cavity and digestive system. It alleviates the symptoms of irritable bowel syndrome (IBS), inhibits inflammations, which helps to decrease permeability of intestines.

Bifidobacterium bifidumcolonizes primarily mucous membrane of the large intestine and reproductive tract of women. It positively modifies microflora of the digestive system, increasing the amount of lactic acid bacteria and decreasing the population of undesirable bacteria (e.g. E. Coli). It breaks down both histamine and tyramine (biogenic amine abundantly appearing in food). In excess it causes migraines and heart rhythm disorders.

Bifidobacterium longuminhabits the digestive system. It increases intestinal tightness, helps in histamine degradation and decreases inflammatory response of the organism after a meal containing histamine. Strengthening the population of these bacteria may decrease the symptoms of histamine intolerance.

Bifidobacterium lactisinhabits mainly the large intestine and the final part of ileum. It regulates bowel movement, decreases ailments of the digestive system. Moreover, it is conducive to the improvement of immunological parameters, decreases the level of pro-inflammatory cytokines and mediators of inflammations. In people who seasonally suffer from allergies, it promotes the desired balance between lymphocytes Th1 and Th2, which is reflected in alleviating the symptoms of allergy. 

Bifidobacterium breveappears in the gastro-intestinal tract and may be found in mother’s milk. It has anti-inflammatory and anti-allergic properties. It maintains proper proportions of Th1 to Th2 and inhibits the production of IgE antibodies. Moreover, it limits degranulation of mast cells.

Lactobacillus salivariusone of the most common kinds of probiotic bacteria. It improves the composition of intestinal microflora and strengthens the immune response. It also produces a range of antimicrobial substances and regulates the level of mediators of inflammation. It may alleviate the symptoms of asthma.

Lactobacillus plantarum possesses incredible ability to adapt and may survive in various temperatures. It demonstrates antioxidant properties, is conducive to maintaining proper intestinal tightness and stimulates regeneration of intestinal lining. It is able to break down histamine and other biogenic amines.

To sum up, Seeking Health ProBiota HistaminX is a preparation from the group of the so-called targeted probiotics. It allows to use the activity of probiotic bacteria in order to alleviate histamine intolerance. At the same time it causes additional benefits of probiotic therapy, i.e. it perfectly regulates the work of the digestive system and strengthens immunity. 

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Container size: 60 capsulesServing size: 1 capsuleServings per container: 60

Other ingrednients

Microcrystalline cellulose, vegetarian capsule (hypromellose, water, gellan gum), L-leucine and silica

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Bifidobacterium infantis


Bifidobacterium infantis – what is it?

Bifidobacterium infantis is a lactic acid bacterium present in the digestive system. It is an anaerobic bacterium, which can convert carbohydrates into lactic acid.

Bacterium is beneficial for people struggling with irritable bowel syndrome, as it reduces bloating and gas, the risk of diarrhoea and abdominal pain. B. infantis can reduce inflammations associated with particular diseases, such as psoriasis, colitis ulcerosa or chronic fatigue syndrome. What is interesting, it can quickly strengthen the intestinal barrier. Thanks to that, it contributes to the proper functioning of the immune system. It will be also helpful in case of intestinal dysbiosis, as it can fight harmful bacteria, by producing factors which will cause their death and competing over receptors in the intestinal lining to which it could attach.

Bifidobacterium bifidum


Bifidobacterium bifidum – what is it?

Bifidobacterium bifidum is a Gram-positive bacteria strain of the Bifidobacterium genus. It is non-motile, anaerobic and rod-shaped. In the human body system, it is present mainly in the large intestine, but also in the final parts of the small intestine, vagina and mother’s milk. It is one of the most commonly used strains in probiotic preparations.

The benefits of the use of probiotics containing this bacterium include smaller risk of diarrhoea, induced both by infections and antibiotics, as well as lower risk of infections caused by Escherichia Coli bacteria. It can be also helpful in restoring bacterial homeostasis in vagina. Bifidobacterium bifidum can contribute to better nutrition of the whole organism, because of its ability to produce particular vitamins from B and K groups. It can be also helpful in regulation of respiratory system functions, thanks to the reduction in histamine production and improvement in antibodies response.

Bifidobacterium bifidum contained in many complex probiotic preparations which can be found in the offer of

Bifidobacterium longum


What is Bifidobacterium longum?

Bifidobacterium longum is one of the most understood strains of probiotic bacteria naturally populating the human body. Like other bacteria of this kind, it promotes the digestion of lactose and other nutrients. Consequently, it helps absorb properly vitamins and nutrients in specific parts of the digestive tract.

Bifidobacterium longum supports the functioning of the immune system and inhibits the development of pathogens, in particular residing in the female vagina, by synthesising lactic acid, lysozyme and other acidic substances.  It contributes to reducing inflammations and lowers cortisol levels. It has also the ability to produce B vitamins.

It is used in medicine in treating disorders of gastrointestinal disorders, such as nausea, constipation and diarrhoea. Due to the presence of this health-promoting strain in breast milk, the supplementation is recommended for gaining the best advantages to child development and health.

This bacteria strain is found mainly in complex probiotic or symbiotic formulas available at

Lactobacillus salivarius


What is Lactobacillus salivarius?

Lactobacillus salivarius is a probiotic bacterium found mainly in the colon, small intestine and vagina, but it has been also detected in the oral cavity. It competes on populated areas with pathogens for a source of nutrients and adhesion site, hereby supporting other friendly bacteria strains in fighting pathogens. By adhering to the intestinal mucosa, it supports the intestinal barrier function. It has also a significant immunomodulatory action. It improves the balance between Th1 and Th1 helper cells in asthmatics, showing consequently an anti-inflammatory action. It inhibits the secretion of proinflammatory cytokines and supports the treatment of many skin allergies.

By producing lactic acid, bacteriocins and small amounts of hydrogen peroxide, it inhibits the growth or reduces the number of fungi of the genus Candida, E.coli, Salmonella ssp., Streptococcus pyogenes and Helicobacter pylori. Along with Bifidobacterium breve, it promotes the removal of Streptococcus mutans in the oral cavity which is responsible for tooth decay, dental plaque formation and mouth ulcers.

Promising results have been also observed in reducing pain. It results from the fact that Lactobacillus salivarius has the ability to induce the expression of receptors associated with pain relief, in particular OPRM1 in the intestines. What is more, it influences the brain-gut connection, hereby improving gut health after taking antibiotics or damaged by pathogens. As a result, it can contribute to improving cognitive functions, reducing depressive states and anxiety. It has also shown a beneficial impact on the cardiovascular system by reducing cholesterol levels and blood pressure.

Lactobacillus salivarius is found mainly in complex probiotic or symbiotic formulas available at

Lactobacillus plantarum


What is Lactobacillus plantarum?

Lactobacillus plantarum is a strain of gram-positive, motionless, rod-shaped bacteria which ferment milk in the intestinal environment. These probotic strains are believed to be the most resistant to adverse conditions prevailing in different sections of the digestive tract. Apart from the small intestine, they were detected in the oral cavity and even vagina where they compete with pathogenic microorganisms, protecting the body from bacterial infections, viruses and mycoses. 

They affect the vitality of pathogens and synthesis of compounds beneficial to the health of, e.g. lactic acid and short-chain fatty acids. As a result, it normalises intestinal function, thereby ensuring proper digestion and nutrient absorption. By using the lactase enzyme, it has the ability to break down milk sugar which is the cause of many unpleasant digestive ailments in the majority of adults.

It is used in medicine for treating irritable bowel syndrome, problems with digestion and Crohn’s disease. It is used in supplementation as one of the components of complex probiotics available at

Bifidobacterium lactis


What is Bifidobacterium lactis?

Bifidobacterium lactis is a strain of probiotic bacteria capable of producing lactic acid which are classifed as gram-positive, rod-shaped bacteria. They populate naturally the end part of the ileum and large intestine. Their main function is to compete for nutrients and adhesion sites with pathogenic bacteria. Their properties can be thus desribed as antidiarrhoeal, regenerating the intestinal mucosa, helping the body take in more micronutrients and regulating intestinal peristalsis. 

This bacteria strain has also the ability to produce lactic acid from lactose or other substances which will hinder indirectly (by acidifying the environment) or directly (by killing bacteria) the growth and survival of such pathogenic bacteria as Salmonella or Helicobacter pylori.

The supplementation with probiotic strains helps restore healthy intestinal microflora which is nowadays disrupted by many negative environmental factors. 

Bifidobacterium breve


What is Bifidobacterium breve?

Bifidobacterium breve is a bacterium naturally residing in the large intestine whose presence and functions have a positive effect on digestion, nutrient absorption and the overall human health. It belongs to nonspore-forming gram-positive bacteria. It is extremely resistant to gastric juices present in different parts of the digestive tract and reach the adhesion site in an adequate amount. It has been demonstrated to have a particular affinity to HT-29 cell line in the intestines.

By producing organic acids and lactic acid, it reduces the alkalinity of the intestines, hereby inducing adverse effects for the development of such pathogens as Clostridium difficile, Helicobacter pylori, E.coli and Candida. Owing to that, it reduces digestive ailments associated with bacterial infection and caused by antibiotherapy. In addition, it has a positive impact in the treatment of candidiasis.

The strains of the genus Bifidobacterium have been detected in breast milk. Owing to that, after passing through the infant’s digestive tract, it shows many benefits to its healthy development. It has an indirect impact on individuals with depression, boosts focus and concentration.

Bifidobacterium breve is found mainly in complex probiotic or symbiotic formulas available at

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