Since 2005
You are currently:
Choose language:
Need help?
Leave message
Choose language:
Select currency: $ £
Since 2005
en
USD
Order:55.00 $111.00 $166.00 $222.00 $
Shipping:-3.00 $-6.00 $-8.00 $-11.00 $
0 0.00 $
Since 2005  sales@mz-store.com  +1 844-530-3647
Lipodrene Hardcore Lipodrene Hardcore

Hi-Tech Pharmaceuticals Lipodrene Hardcore is a complex of ingredients containing many plant extracts, as well as isolated active substances that will effectively ensure an increase in metabolic rate and effective fat burning, as well as contribute to the delaying of the feeling of hunger.

Ephedra leaf extract is a source of substances that affect adrenergic receptors, which act using mainly beta receptors and may contribute to increased heat production in muscle tissue, thereby stimulating the burning of energy substrates, including fats released from adipocytes. Besides, the extract may reduce glucose uptake by adipose tissue cells, preventing fat deposition. Moreover, supplementation with Ephedra extract may promote an increase in blood pressure since it binds to alpha receptors on the precapillary sphincters.

Senegalia Berlanderi leaf extract contains a set of centrally acting substances. They facilitate adrenergic transmission, mainly with regards to norepinephrine, which contributes to increased peripheral lipolysis. Besides, their derivatives as well as phenylethylamine itself are known for their euphoric effect, thanks to which they improve well-being.

Citrus Aurantium extract is the main source of phenylethylamine, which at the molecular level binds to TAAR1 receptors in the central nervous system, inhibiting the reuptake of dopamine, serotonin, and noradrenaline. Dopamine and serotonin, as "happiness hormones", are responsible for improving mood and a feeling of pleasure, while noradrenaline increases blood pressure and helps to release triglycerides from adipocytes.

1,3-Dimethylamylamine (DMAA), otherwise known as geranium, is a substance whose action is based on blocking noradrenaline reuptake, thanks to which it stimulates the central nervous system, affecting the increase of exercise capacity, reduction of fatigue and acceleration of metabolism. Another desirable action of geranamine is a significant increase in thermogenesis.

Cassia Nomame extract has an inhibitory effect on the action of an enzyme called pancreatic lipase, which is involved in the process of breaking down fats. It enables their conversion into monoglycerides and fatty acids, followed by their absorption in the small intestine. The lack of this process reduces the amount of calories consumed with food, thus facilitating the achievement of caloric deficit and reduction of body fat by initiating lipolysis.

Naringen is a plant-derived compound belonging to flavonoids that has a broad spectrum of activity. It helps in the fight against excess body fat and lipid panel disorders, as it can induce adipocyte apoptosis and also inhibit one of the key enzymes in cholesterol production – HMG-CoA reductase. In addition, it has been proven to have anti-inflammatory and antioxidant effects.

6,7-Dihydroxybergamotin is contained in grapefruit juice and shows quite a specific inhibitory activity against the enzymatic complex in the liver – cytochrome P450. It is responsible for the metabolism of many substances, including drugs. As an addition to supplements, it is designed to facilitate their bioavailability.

Evodiamine is an alkaloid isolated from fruit found in China. It contributes to the increased production of catecholamines, which directly increase the concentration of cAMP in adipose tissue cells, enabling their emptying.

5-methoxytryptamine hydrochloride is a full agonist of serotonin receptors in the central nervous system. The compound is credited with the ability to affect the secretion of leptin, a 'satiety hormone' that prevents excessive snacking and facilitates weight control.

Yohimbe extract is characterized by the presence of yohimbine, a chemical compound that acts as an alpha2 receptor antagonist, thanks to which it allows the release of noradrenaline without its inhibition. Substances belonging to polyphenols and other chemical compounds found in the extract, in turn, contribute to the improvement of insulin sensitivity of cells, blood lipid profile, and muting existing inflammatory processes.

Yerba Mate Extract – an extract of dried leaves of Ilex Paraguariensis, a tree growing in South America. It is rich in various bioactive substances, including polyphenols and purine alkaloids. Yerba Mate, by modulating the signaling pathways that regulate the process of adipogenesis, inhibits the preadipocyte differentiation and decreases the accumulation of fat and inflammation occurring within the fat tissue. Thanks to the content of chlorogenic acid, it modulates the activity of glucose-6-phosphatase, an enzyme involved in glucose metabolism. Also, it optimizes the lipid profile and has antioxidant and stimulating effects.

Green tea extract is a wealth of ingredients, mainly methylxanthines, as well as epicatechins. The latter contribute, among others, to decreasing the perceived hunger by affecting the secretion of neurotransmitters as well as delaying gastric emptying. They may also sensitize the tissues to insulin.

Theobroma Cacao extracta source of theobromine, methylxanthine, which in addition to the participation in fat burning allows for more effective absorption of epicatechins contained in green tea extract. It also improves the lipid profile, shows anti-inflammatory properties, and may also lower blood pressure.

To sum up, Hi-Tech Pharmaceuticals Lipodrene Hardcore is a supplement intended primarily for people who want to intensify the process of body fat reduction. The combination of ingredients inducing catecholamine and methylxanthine secretion will enable the enzymatic apparatus of the lipolysis process, whereas the polyphenols, epicatechins, and pancreatic lipase inhibitors will contribute to additional effects in the form of delayed hunger, tissue sensitization to insulin, or reduction in caloric intake.

 

InStock
Since 2005
Add to Cart
Lipodrene Hardcore Lipodrene Hardcore 90 tab. (DMAA version)
Hi-tech
59.43 $

Lipodrene Hardcore 90 tab. (DMAA version)

Servings: 90 tab. (DMAA version)

All variants:

1-2
Location:
UK Stock
Availability:
Big amount
Working days
from the dispatch
Minimum expiration date:
2022-06
For free shipping is missing: 167.00 $
59.43 $With VAT
1 Units.
Add to Cart

Customer Service

(mon.-fri 900-1700

You have got questions about the product

Description
  • A complex of substances that maximally enhance stimulation and motivation
  • Maximizes the rate of burning extra body fat
  • Stimulates the physiological mechanisms involved in fat burning
  • Helps to reduce the absorption of unnecessary calories from food
  • Supports insulin and carbohydrate metabolism
  • Inhibits the development of harmful inflammatory processes
  • Intensifies cAMP production
  • Helps to control the appetite
  • Safe to use

Hi-Tech Pharmaceuticals Lipodrene Hardcore is a complex of ingredients containing many plant extracts, as well as isolated active substances that will effectively ensure an increase in metabolic rate and effective fat burning, as well as contribute to the delaying of the feeling of hunger.

Ephedra leaf extract is a source of substances that affect adrenergic receptors, which act using mainly beta receptors and may contribute to increased heat production in muscle tissue, thereby stimulating the burning of energy substrates, including fats released from adipocytes. Besides, the extract may reduce glucose uptake by adipose tissue cells, preventing fat deposition. Moreover, supplementation with Ephedra extract may promote an increase in blood pressure since it binds to alpha receptors on the precapillary sphincters.

Senegalia Berlanderi leaf extract contains a set of centrally acting substances. They facilitate adrenergic transmission, mainly with regards to norepinephrine, which contributes to increased peripheral lipolysis. Besides, their derivatives as well as phenylethylamine itself are known for their euphoric effect, thanks to which they improve well-being.

Citrus Aurantium extract is the main source of phenylethylamine, which at the molecular level binds to TAAR1 receptors in the central nervous system, inhibiting the reuptake of dopamine, serotonin, and noradrenaline. Dopamine and serotonin, as "happiness hormones", are responsible for improving mood and a feeling of pleasure, while noradrenaline increases blood pressure and helps to release triglycerides from adipocytes.

1,3-Dimethylamylamine (DMAA), otherwise known as geranium, is a substance whose action is based on blocking noradrenaline reuptake, thanks to which it stimulates the central nervous system, affecting the increase of exercise capacity, reduction of fatigue and acceleration of metabolism. Another desirable action of geranamine is a significant increase in thermogenesis.

Cassia Nomame extract has an inhibitory effect on the action of an enzyme called pancreatic lipase, which is involved in the process of breaking down fats. It enables their conversion into monoglycerides and fatty acids, followed by their absorption in the small intestine. The lack of this process reduces the amount of calories consumed with food, thus facilitating the achievement of caloric deficit and reduction of body fat by initiating lipolysis.

Naringen is a plant-derived compound belonging to flavonoids that has a broad spectrum of activity. It helps in the fight against excess body fat and lipid panel disorders, as it can induce adipocyte apoptosis and also inhibit one of the key enzymes in cholesterol production – HMG-CoA reductase. In addition, it has been proven to have anti-inflammatory and antioxidant effects.

6,7-Dihydroxybergamotin is contained in grapefruit juice and shows quite a specific inhibitory activity against the enzymatic complex in the liver – cytochrome P450. It is responsible for the metabolism of many substances, including drugs. As an addition to supplements, it is designed to facilitate their bioavailability.

Evodiamine is an alkaloid isolated from fruit found in China. It contributes to the increased production of catecholamines, which directly increase the concentration of cAMP in adipose tissue cells, enabling their emptying.

5-methoxytryptamine hydrochloride is a full agonist of serotonin receptors in the central nervous system. The compound is credited with the ability to affect the secretion of leptin, a 'satiety hormone' that prevents excessive snacking and facilitates weight control.

Yohimbe extract is characterized by the presence of yohimbine, a chemical compound that acts as an alpha2 receptor antagonist, thanks to which it allows the release of noradrenaline without its inhibition. Substances belonging to polyphenols and other chemical compounds found in the extract, in turn, contribute to the improvement of insulin sensitivity of cells, blood lipid profile, and muting existing inflammatory processes.

Yerba Mate Extract – an extract of dried leaves of Ilex Paraguariensis, a tree growing in South America. It is rich in various bioactive substances, including polyphenols and purine alkaloids. Yerba Mate, by modulating the signaling pathways that regulate the process of adipogenesis, inhibits the preadipocyte differentiation and decreases the accumulation of fat and inflammation occurring within the fat tissue. Thanks to the content of chlorogenic acid, it modulates the activity of glucose-6-phosphatase, an enzyme involved in glucose metabolism. Also, it optimizes the lipid profile and has antioxidant and stimulating effects.

Green tea extract is a wealth of ingredients, mainly methylxanthines, as well as epicatechins. The latter contribute, among others, to decreasing the perceived hunger by affecting the secretion of neurotransmitters as well as delaying gastric emptying. They may also sensitize the tissues to insulin.

Theobroma Cacao extracta source of theobromine, methylxanthine, which in addition to the participation in fat burning allows for more effective absorption of epicatechins contained in green tea extract. It also improves the lipid profile, shows anti-inflammatory properties, and may also lower blood pressure.

To sum up, Hi-Tech Pharmaceuticals Lipodrene Hardcore is a supplement intended primarily for people who want to intensify the process of body fat reduction. The combination of ingredients inducing catecholamine and methylxanthine secretion will enable the enzymatic apparatus of the lipolysis process, whereas the polyphenols, epicatechins, and pancreatic lipase inhibitors will contribute to additional effects in the form of delayed hunger, tissue sensitization to insulin, or reduction in caloric intake.

 

Directions for use
Manufacturer
Reviews (0)

Composition

Container size: 90 tabletsServing size: 1 tabletServings per container: 90
per 1 tabletamount%DV
Proprietary Blend with Thermo-RX® & Extend-Rx™ Technologies325 mg**
Ephedra Extract (leaves), Senegalia Berlanderi Extract (leaves) [Yielding 200mg Phenylethylamine Alkaloids, Including
Methylsynephrine
N-Methyl-B-Phenylethylamine
N,N Dimethylphenylethylamine and Phenylethylamine]
Citrus Aurantium 60% Extract (supplying 20 mg Synephrine alkaloids)
1,3-Dimethylamylamine
Cassia Nomame Extract (plant)
Naringen (fruit)
6,7 Dihydroxybergamottin (fruit)
Evodiamine
5-Methoxytryptamine HCl
Yohimbe 8% Extract (bark)
Proprietary Tri-Xanthine™ Blend375 mg**
Yerba Mate Extract, Green Tea Extract, and Theobroma Cocoa Extract (standardized to 200mg Caffeine, 45mg EGCG, 25mg Theobromine, and 40mg Theophylline)

Other ingrednients

Dextrose, microcrystalline cellulose, hydroxypropyl methylcellulose, stearic acid, magnesium stearate, sodium starch glycolate, starch, triacetin, titanium dioxide, silica, FD&C blue #1, FD&C red #40

 

Similar products
Best to combine with
Activlab
16.01 $
(13)

High quality BCAA amino acids with L-glutamine. Accelerate the regeneration and improves anabolism.

Buy
Biotech Usa
18.72 $

The highest-quality source of BCAA in the proportion 2:1:1 enriched in glutamine and vitamin B6.

Buy
Olimp
12.21 $
(1)

BCAA capsules. It works anabolic and anti-catabolic, improves endurance and helps regeneration.

Buy
Olimp
26.87 $

The supplement promotes the nourishment of muscle tissue, increases its efficiency and speeds up regeneration.

Buy
Olimp
23.07 $
(3)

Dietary supplement with glutamine. Rapid recovery after training. Increases and inhibits catabolism.

Buy
Trec
3.26 $
(2)

Capsules with the branched amino acids and L-glutamine. They increase strength and endurance.

Buy

Proprietary blend

Information

Proprietary blend - is a complex of bioactive ingredients in the proportions, which are covered by the manufacturer's patent. According to the law in force in Poland, the components of the blend are known, and , by the place on the packaging, you can identify which components are in bigger amount (the components are listed in the decreasing order of amounts).
Proprietary blends are used in many food supplements, such as creatine stacks, no-boosters, fat burners and pro-testosterone supplements, improving libido.


 

Synephrine

Information

Synephrine is an organic compound from harvested on an industrial scale the fruit of bitter orange (Citrus aurantium). Citrus auratuim extract (extract of bitter orange) is widely used in the process of weight reduction, both among athletes, active individuals, as well as leading the so-called. "sedentary lifestyle". It is a source of synephrine and octopamine, which in combination with caffeine and polyphenols contained in green tea affect lipolysis, releasing fatty acids adipocytes, by causing increased energy expenditure, burning them in the sources of vital energy cells (mitochondria). It is popular on the banning of ephedra by WADA (dangerous for the body). Contraindication to use preparations against people with hypertension. In the sports supplementation is available in body mass reduction and sculpting programs, as a thermogenic, creatine stacks and nitrogen boosters ingredient.
Dosage: No standards unit consumption. In the supplementation - customarily - 10-30 mg


 

Cassia Nomame

Information

Cassia Nomame – wild herbaceous plant, willingly used in traditional Chinese medicine. It demonstrates dehydrating and laxative properties and has been used in problems with constipations.  It was noticed that one of side-effects of its application is weight loss, therefore it started to be used as an element of weight loss supplements.

However, according to the current knowledge on this plant, its abilities to stimulate fatty tissue reduction do not result from its laxative properties. Cassia Nomame provides compounds which are natural inhibitors of lipase, therefore it limits the absorption of fat in the human organism.

There are also sources which indicate that Cassia Nomame may have thermogenic effect and may stimulate metabolic rate. It makes the extracts from this plant an ideal ingredient of fat burners.

Apart from this, the plant has pro-health properties. It may have anti-inflammatory effect, due to which it is recommended in the therapy of arthritis. Some sources also suggest positive influence of Cassia Nomame among people suffering from migraines.

Importantly, Cassia Nomame cannot be taken by pregnant and breast-feeding mothers and people below the age of 18.

Evodiamine

Information


Evodiamine is an alkaloid with thermogenic and stimulating effect, allowing for faster burning of lipids, with an action similar to capsaicin. Source of evodiamine is plant of the family Rutacea. In the sports supplementation, its thermogenic potential is used in the combination with caffeine and green tea, as part of enhancing body fat reduction, improveing the body composition and aesthetics. It is also used by people with low physical activity in the weight loss process. It is a component of stimulating supplements (boosters and pre-workout creatine stacks)

 

5-Methoxytryptamine

Information

5-Methoxytryptamine - a compound naturally occurring in the human organism. Enriched in one acetyl group, it creates a hormone melatonin and it is structurally similar to serotonin. It is also known as mexamine.

Biological activity of 5-metoxytryptamine should be considered due to its structural similarity to serotonin. It is an agonist of serotonin receptors 5-HT1, 5-HT2, 5-HT4, 5-HT6 and 5-HT7. Because of this, it has stimulating influence on the functioning of the organism and increases the level of cyclic adenosine monophosphate in cells. Thanks to this, it stimulates metabolism and increases the effectiveness of stimulating catecholamines. Because of this activity, it is used in fat burners in order to maximize the pace of weight loss.

Some source also suggest the ability of 5-methoxytryptamine to promote cognitive functions.

Yerba Mate

Information

Yerba Mate extract - from the leaves of yerba mate (ilex paraguariensis), a drink popular in South American countries. The extract contains caffeine (as metaine) and is a powerful antioxidant. Teas and extracts of Yerba Mate leaves are slimming by causing a feeling of satiety and fat absorption, increase immunity of DNA through the binding of free radicals, reduce LDL cholesterol levels.
In the sports supplementation, the ursolic acid contained in the yerba mate, may be important, as it is an aromatase inhibitor, capable of lowering estrogen levels of men, thereby affecting the aesthetics of the figure. Yerba mate extract is a component of fat burners. In combination with green tea, bitter orange and black pepper (piperine) it increases thermogenesis.
Dosage: the lack of standards for daily consumption.

Green tea extract

Information

Green tea extract is a concentrate that contains biologically active compounds: polyphenols (e.g. catechin, in the form of EGCG - epigallocatechin gallate), having antioxidant properties and a small thermogenic potential, modifies the action of testosterone metabolites, DTH. Green tea extract is an ingredient of many sports supplements containing fat burners, having pro-health and vitaminizing effect; also for those with low physical activity as an antioxidant and slimming supplement. Available either as mono-preparations, ready drinks, and above all as an extract.
Dosage: 200-500 mg per day (depending of the content of other active bio-components).


 

Caffeine

Information

Caffeine (1,3,7-trimethylxanthine, 1-methylotheobromine) is a purine alkaloid occurring in the natural state in plants (Coffea arabica, Camelia sinensis, Paulinia cupana, Ilex paraguariensis), which acts as a natural pesticide, acting toxic to insects. Peculiar smell and taste also deters herbivores. Caffeine in the body inhibits the adenosine receptors in the brain, fighting fatigue and allowing for action activation. It has a beneficial effect on the metabolism of oxygen, which increases the exercise capacity (strength and endurance) and rapid post-workout recovery. In the sports supplementation, caffeine is used as a stimulant nervous system. It has the thermogenic potential and in combination with other substances (e.g. Polyphenols, both occurring in coffee beans, such as cocoa beans, tea leaves and mate) can effectively participate in the reduction of body fat. It is included in many dietary stimulants (creatine stacks, no-boosters, beverages). It is a component of fat burners. It is also in the form of mono-preparation supplements.
Dosage: 100-600 mg per day. Due to the long release of activity should not be used in the evening, before
sleep.


 

EGCG

Information


EGCG (epigallocatechin gallate) - a compound occurring naturally in the leaves of green tea and sage nutmeg. Powerful antioxidant resulting in removing free radicals out of your body. It has the thermogenic potential (enhanced when combined with other substances including caffeine, capsaicin, etc.), allowing a faster fat reduction. Affects preventively in the side effects of the glandular hypertrophy (prostate) and male pattern baldness. Recommended for those who are active physically and professionally, for the maintenance of body composition and body aesthetics. It is a component of fat burners, allowing for faster slimming.
Dosage: 50-500 mg per day.

 

Theobromine

Information


Theobromine (3,7-Dimethylxanthine) is a purine alkaloid, poorly soluble in water, present in cocoa beans, as well as the leaves of yerba mate, tea, coffee, cola and peanuts. It is a diuretic, lowers blood pressure and improves brain function (dilates the blood vessels of the brain). Also expands the blood vessels throughout the circulatory system, preventing atherosclerotic changes. Sometimes it is used in slimming diet. Combined with caffeine and polyphenols becomes thermogenic. In the sports supplementation formulations containing theobromine are used diuretics and fat burners. It is a component of thermogenics, pre-workout creatine stacks, as well as nitrogen boosters.

Theophylline

Information

Theophylline is a natural compound from the group of methylxanthines, which is currently obtained also in a synthetic way. In natural conditions, theophylline can be also found in i.a. tea leaves and cocoa beans.

It has anti-inflammatory and relaxing effect, therefore as a drug it finds application in the treatment of asthma. In case of theophylline - as an ingredient of dietary supplements - the mechanism based on inhibiting the activity of phosphodiesterase is the most important here - an enzyme responsible for cAMP breakdown. Theophylline, by being an inhibitor of this enzyme, contributes to the increase of intracellular concentration of cyclic AMP, at the same time increasing thermogenic and lipolytic processes and increasing the ability to concentrate as well as reducing the feeling of fatigue.

Therefore, theophylline demonstrates similar activity to caffeine, additionally positively influencing respiration and improving blood flow through kidneys. These properties makes theophylline a valuable ingredient of fat burners and pre-workout supplements.

Latest on blog

Sign up for our newsletter
And receive coupons, news, special offers and much more!

Customer service

MZCatalog - recommended dietitians

MZCatalog - recommended trainers

MZCatalog - recommended clubs

Supps4You LLC
16192 Coastal Hwy Lewes, Delaware 19958
sales@mz-store.com +44 7767803657