• Vitamin D3 at the dose of 2500 IU
• Wide spectrum of effects
• Helps to maintain healthy and strong bones
• Is conducive to proper work of the nervous system
• Helps to “calm down” inflammations in the organism
• Regulates calcium-phosphorus metabolism
• Positively influences mental well-being
• Supports mineral balance of bones
• Contributes to the increase of immunity
• Friendly to vegans and vegetarians

Doctor's Best Vegan D3 2500 IU is a dietary supplement, providing vitamin D3 (cholecalciferol) of plant origin at the dose of 2500 IU.

The preparation is in the form of capsules, thanks to which it is characterized by high effectiveness. It was proven that the time of the capsule’s breakdown is 4 times shorter than in case of a tablet, which means that vitamin D3 in this form may demonstrate considerably higher bioavailability.

Vitamin D3, discovered in 1922 by McCollum, since recently, it has been one of the most valued vitamins. Currently, it is more often called a prohormone. Vitamin D3, also called cholecalciferol, is produced in skin from 7-dehydrocholesterol, under the influence of UVB radiation. It may be also obtained with food.

It was believed for a long time that the role of vitamin D is mainly based on maintaining proper bone metabolism and calcium balance. This changed when in 1979, thanks to Stumpf laboratory, a receptor for vitamin D was discovered - VDR (Vitamin D Receptor) and it was proven that it is present in the majority of human extra-skeletal cells. This caused that vitamin D started to be attributed an increasingly higher and meaningful role in the functioning of the whole organism. Currently, its important participation in immunological and anticarcinogenic processes is highlighted.

Vitamin D deficiency is a very common phenomenon all around the world in all age groups. Both insufficient synthesis of vitamin D under the influences of sun, resulting from i.a. geographical and seasonal differentiation as well as insufficient supply with a diet (including also coexisting absorption deficiencies and diseases inhibiting absorption) only deepen this problem.

Recent research proved that deficiency of vitamin D may be the cause of many diseases, including: cancers, diabetes, hypertension, autoimmune diseases, neurological diseases, diseases of the skeletal system (decreased movement efficiency, worse work of muscles).

The influence of vitamin D3 on the skeletal and muscle system is the best-known. This vitamin enables proper bone mineralization, maintains proper relation between bone formation and resorption, at the same time reducing bone turnover and leading to the increase of bone mass.

Vitamin D also takes part in the activation of numerous metabolic processes taking place in muscle tissue. This vitamin i.a. stimulates the synthesis of protein and influences the proliferation of muscle cells. It was proven that even slight deficiency of vitamin D3 may lead to decreasing the strength of skeletal muscles. Its proper supply positively influences their functioning and facilitates regeneration e.g. after fractures.

Immunomodulating effect of vitamin D is related to i.a. its influence on the level of cathelicidin. Cathelicidin is a peptide characterized by a wide spectrum of antibacterial effects. It was proven that increasing active metabolites of vitamin D in blood contributes to the increased synthesis of the above mentioned peptide. Moreover, vitamin D leads to decreasing inflammatory reaction (it decreases the level of pro-inflammatory cytokines and increases the level of anti-inflammatory cytokines), counteracting chronic inflammations and autoimmune diseases, such as: rheumatoid arthritis, non-specific inflammatory bowel disease, fybromyalgia.

Vitamin D demonstrates neuroprotective effect, related mainly to its ability to stimulate the synthesis of neurotransmitters and especially dopamine, the insufficient level of which is the only active factor of Parkinson’s disease. It was proven that deficiency of vitamin D influences deterioration of well-being and the occurrence of depression symptoms and it often accompanies people dealing with cognitive disorders.

To sum up, Doctor's Best Vegan D3 2500 IU is a dietary supplement, which helps to level up deficiency of vitamin D. It is especially recommended to people who avoid exposure to sun and whose diet is poor in products which are the source of vitamin D.

It is also recommended in the winter period, during which skin synthesis of vitamin D is decreased (it helps to decrease the frequency of upper respiratory tract infections). Including vitamin D to constant supplementation may be also one of the key elements of prophylaxis of civilization diseases, and it may also constitute perfect support for physically active people.