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Apollo’s Hegemony K2 Mk7 is a dietary supplement containing 100 mcg of vitamin K2 in the form of Mk7 per capsule.
Vitamin K2 (menaquinone) – a fat-soluble substance of the K complex, it has difarnesyl residue or other isoprene groups in the third position. It is produced mainly in fermentation processes, as well as in the lumen of the intestine by natural bacterial flora. Small amounts of K2 Mk7 can be converted from vitamin K1 (phylloquinone) with the aid of bacteria Escherichia coli. The main activity of vitamin K2 consists in activating osteocalcin – a hormone produced by osteoblasts that supports the transport of calcium to bones and exhibits many other properties beneficial for health.
Differences between K1 and K2
The activity of vitamins K1 and K2 is fundamentally different and they should not be confused. Vitamin K1, commonly just called vitamin K, is responsible mainly for regulating blood coagulation processes. On the other hand, menaquinone, vitamin K2, exhibits the property to a much smaller degree; however, it is an important player in calcium management in the organism.
The form Mk7 is characterised by a longer molecule chain as compared to the popular form – Mk4. Thanks to that, its release is longer and the increase of the vitamin in the blood is more stable. Mk7 also requires much smaller doses to achieve proper efficacy. For example, the minimum efficient dose of Mk4 is 1,500 mcg, although therapeutic doses reach up to 45,000 mcg; on the other hand, efficient doses of Mk7 are even 90-360 mcg.
Synergy with vitamin D3
Vitamin K2 is a popular complement to vitamin D3 supplements, as it reduces the risk of potential damage caused by large doses of cholecalciferol. Vitamin D significantly improves calcium absorption, which can pose a problem if its use by the organism, that is its transport to bone tissue, is not optimised. Menaquinone comes in handy thanks to its ability to activate the hormone produced by bones – osteocalcin. The substance is responsible for calcium transport to teeth and bones, where it is needed most. That way, the amount of free calcium circulating in the blood decreases. Apart from reducing damage, both vitamins can stimulate each other’s activity, for example, when it comes increasing testosterone levels, improving insulin sensitivity, or protecting the nervous system.
Healthy circulatory system
One of the diseases of affluence that are particularly problematic for seniors is atherosclerosis. Contrary to the common belief, cholesterol levels are not the only factor that can contribute to the formation of atherosclerotic plaque in blood vessels. Elevated calcium levels can also prove problematic; calcium can be deposited in soft tissues, such as vessel walls, and make them stiff. Calcifications can also contribute to an increase in blood pressure and the breaking of capillaries.
Tougher and stronger bones
Osteocalcin produced by osteoblasts and stimulated transport of calcium to bones translates into greater bone mineral density and their tougher structure. Another vitamin K-dependent factor that directs calcium ions to the right places is Matrix Gla Protein (MGP). Activating the two factors allows more efficient distribution of calcium in the organism, delivering it exactly where it should be. As research shows, menaquinone supplementation significantly reduces the risk of fractures.
In service of the brain
Vitamins K are present in the brain, where their beneficial activity can also be experienced. The most important property is their neuroprotective effect, preventing the death of cells caused by various factors. Among them are some types of oxidative stress, including that caused by mercury, and excitotoxicity induced by the excessive activity of glutamate. Inhibiting the enzymes 12-LOX helps to reduce inflammations in the brain. Moreover, vitamin K, similarly to vitamin D, helps to protect neurolemmas, which is particularly important for people struggling with multiple sclerosis. Scientists have demonstrated a correlation between low vitamin K levels and distorted cognitive processes in seniors.
Additional benefits of osteocalcin
The protein hormone has many other interesting properties that go beyond just calcium management. One of them is its ability to stimulate Leydig cells in nuclei, thanks to which they can produce more testosterone, which should be particularly interesting for men struggling with low levels of the androgen and fertility problems. Osteocalcin also affects insulin production by pancreatic beta cells and their proliferation, stimulating adiponectin release from adipose cells, thanks to which insulin sensitivity is improved.
Apollo’s Hegemony K2 Mk7 is recommended particularly for people with an increased risk of circulatory system diseases, especially atherosclerosis. It can also efficiently increase bone mineral density and toughness, which is useful in preventing osteoporosis and in other diseases of the musculoskeletal system. A common practice is combining vitamin K2 with larger doses of vitamin D3 in order to reduce the risk of complications and achieve synergy.
The recommended dosage that efficiently increases the level of the vitamin ranges from 90 to 360 mcg, so the dosage of the supplement should be 1 to 3 capsules a day, depending on the purpose of using it.
Vitamin K2 is usually used as a complement for vitamin D3 supplementation. In that case, it is good to include at least 100 mcg of K2 for every 5,000IU of vitamin D.
2-3 capsules a day are worth taking when there are already calcifications and stiffness of blood vessels, as they can help to reverse the effect. The dose can also be used for strengthening the bones and reducing the risk of osteoporosis.
When it comes to preventive healthcare and supplementation, one capsule a day should suffice. The time of taking the supplement is not clearly defined, it should be adjusted to the effects achieved. For better absorption of the vitamin, it is recommended to take the capsules during or right after a high-fat meal.
Apollo’s Hegemony is a manufacturer of dietary supplements whose composition is based on the latest scientific research and experience. The company is constantly expanding its range of products and taking care that they are of top quality.
It offers formulations which have multiple effects on the body and those with more targeted effects – e.g. boosting alertness and focus, increasing the tolerance to stress, promoting peaceful sleep and maintaining the health of the liver and adrenal glands.
Dietary supplements by Apollo’s Hegemony are effective owing to carefully selected composition which comprises the most potent forms and their precise doses. What is more, herbal supplements contain standardised extracts.
All products of this brand comply with good manufacturing practices (GMP) and their ingredients are vegan and vegetarian friendly.
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Microcrystalline cellulose, capsule shell (vegetable cellulose).
The product has not been tested for substances banned by the World Anti-Doping Agency (WADA).
What is Vitamin K2?
Vitamin K2 belongs to fat-soluble vitamins It is an important activator of many enzymes and proteins It shows a positive action on calcium balance by activating MGP protein and osteocalcin. This results in the removal of calcium deposits from blood vessel walls and transport of ions of this element to the area where it fulfills its function – teeth and bones. It reduces therefore the calcification of blood vessels and thus the risk of cardiovascular diseases. Moreover, it is a constituent of coagulation factors and cosequently prevents haemorrhages. It shows a synergistic action in combination with vitamin D and magnesium.
Vitamin K2 in the form of a dietary supplement of renowned brands e.g. Now Foods, Swanson, Life Extension, Jarrow Formulas and Thorne Research) can be found in formulas available at www.muscle-zone.pl
What is menaquinone-7?
Menaquinone-7 is a term used for long-chain form of vitamin K2, having seven isoprene residues in the side chain. Contrary to another popular form MK-4, it is not synthesized in tissues, however, it may be produced in the intestines by means of the conversion from vitamin K1 by intestinal bacteria.
It exhibits especially positive influence on the health of the circulatory system, especially by lowering the risk of atherosclerosis and heart attacks. It owes this effect mainly to osteocalcin, activated by vitamin K2. This hormone is responsible among others for the transport of calcium to bones, which counteracts its storage in soft tissues, decreasing at the same time the probability of blood vessel calcification and the creation of atherosclerotic plaques. K2 MK-7 also contributes to protecting the nervous system, securing neurons from excitotoxicity induced by excessive activity of glutamate and reducing the consequences of excessively low level of glutathione.
Vitamin K2 in the form of menaquinone-7 is a very popular additive to supplements with vitamin D3, due to the synergy of effects and reducing potential negative effects of applying higher doses of cholecalciferol.
Menaquinone-7 may be found both in monopreparations and complex supplements in the offer of muscle-zone.pl.
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