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MPA PharmGrade is a dietary supplement containing a blend of amino acids BCAA (leucine, isoleucine, vanillin) and EAA (lysine, phenylalanine, threonine, histidine, methionine). Such combination supports regeneration and limits catabolic processes in muscle tissue, both immediately after training as well as in the longer period of time.
One portion the preparation also contains 3000 mg of coconut water extract, which is the source of calcium, iron, magnesium, phosphorus and manganese. It contains electrolytes supporting proper hydration of the system (sodium, magnesium, calcium, potassium and phosphorus). Sodium and potassium takes part in the transport of amino acids to muscle cells.
Amino acids are necessary in the synthesis of all proteins, including also muscle tissue. Proteins play the role of enzymes, hormones and antibodies and are the principal building elements of all tissues in the human body. The intake of the appropriate amount of protein and amino acids may contribute to the optimal structure of muscle mass and proper functioning of the whole organism.
Synthesis and repair of muscle tissue
The dose of amino acids, that you ensure by drinking refreshing PharmGrade provides muscle tissue with nutrients for optimal regeneration and muscle growth. MPA made sure that proper amino acids are provided in proper amounts. Two scoops contain as much as 12 g of BCAA, including the king of all amino acids when it comes to building muscles – 6 g of leucine!
Leucine is one of three branched chain amino acids, often called the “main” ingredient of one of the most popular supplements – BCAA. It plays the function of the activator of a protein known as mTOR kinase, which induces the synthesis of muscle proteins. Research proves that after-training dose of 5 g of leucine is a much better solution than supplementing whey protein or other source of animal protein.
The supplement also contains essential amino acids (EAA), which the organism needs to obtain with food, as it cannot produce them on its own. Stress induced by hard trainings may cause homeostasis disorders. Providing a proper amount of exogenous amino acids in a diet of active people is incredibly important and may help to maintain balance in the organism by intensifying regeneration and protecting muscles from catabolism.
EAA also contribute to strengthening the effect of the so-called “muscle pump”. It happens, as to a certain extent they has a relaxing effect towards blood vessels and they take part in the synthesis of nitric oxide (NO). Nitric oxide, on the other hand, to a certain extent is conducive to the processes of protein synthesis. In the world of bodybuilding sport it is also said that essential amino acids support the processes of effective weight loss. There are certain opinions than EAA cause the intensification of fatty tissue breakdown, increased metabolic rate and thermogenesis.
Summing up, MPA PharmGrade is a dietary supplement, the proper and systematic application of which limits catabolism and supports muscle tissue regeneration. As the preparation with a universal effect it will work well both during building muscle ass and reducing fatty tissue.
In the periods of fatty tissue reduction, in order to limit muscle tissue catabolism, it is recommended to apply at least half a recommended portion (1 scoop) to min. 2 meals consumed after resistance training.
During building muscle mass, in order to improve anabolic processes, it is recommended to take 1 scoop 2 to 6 times a day, between meals.
In order to increase endurance during training and improve after-training regeneration, it is recommended to take 1-2 portions (2-4 scoops) dissolved in water and sip during training.
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|per portion (19.1 g||amount||%DV|
|Sodium (as Himalayan Pink Sea Salt)||125mg||5%|
|Coconut Juice Powder (Cocos Nucifera) (Coconut Water)||3000mg||**|
|L-Lysine HCL (AjiPure®)||250mg||**|
|L-Histidine HCL (AjiPure®)||250mg||**|
Citric acid, silica, natural and artificial flavoring, sucralose, tartaric acid, acesulfame K
Sodium is an important component of the intracellular fluids, and is a regulator of acid-base balance. Along with potassium affects the proper of growth and provides the proper functioning of muscles and nerves. The source of acquisition is table salt (NaCl) and bladderwrack, shellfish, bacon, beef, and of plant beets and carrots. People on salt-free diet should avoid, among others, spicy sauces and smoked meats and sausages.
Sodium deficiency is very rare, at heaving sweating after a long effort (e.g. in the marathon).
Excess sodium increases blood pressure (especially for the elderly), edema and increased thirst. Exceeding the daily dose of 14g a day can cause poisoning.
Salt (sodium chloride, or table salt), natural source of electrolytes (chlorine and potassium), regulating water and electrolyte and acid-base balance of the body, affecting the nervous system and blood pressure. Sodium is an essential element for the proper growth. The proper dose of salt prevents overheating of the body and solar stroke. It provides the proper functioning of muscles and nerves the body. Chlorine in combination with sodium, is involved in the digestive process and maintains acid-base balance in the body, as antitoxin removes toxic products of metabolism in the liver. Salt is a flavour component and preservative of many foods, nutritional supplements and mixtures of electrolytes, available at www.muscle-zone.pl
Dosage: no specific standards of consumption, used so as to provide sufficient amount of electrolytes to the body (sodium and chloride).
Leucine is an essential amino acid, one of the three branched chain amino acids, ketogenic, its isomer is isoleucine. It affects the secretion of anabolic hormones (insulin, combined carbohydrates), acts on enzymes (mTOR) starting the process of muscle protein synthesis and controlling its course. Protein synthesis by leucine is affecting the development of bones, muscles and skin. It reduces the fat tissue. Without the availability of leucine, protein synthesis is impossible. It naturally occurs in animal products (such as eggs, meat, dairy and fish), plant origin, and as a post-training supplements, BCAA, EAA, no-boosters, creatine stacks, carbohydrate supplements. Ir is also in the form of mono-preparation supplements. It is one of the most important amino acids for the athlete's body, basically in every sports discipline.
Dosage: The demand is 5-10 g / 24h, dosage pre- and post-workout and in the morning after waking up.
Valine – is a branched essential amino acid, indispensible for the functioning of the nervous system (receiving of sensory information), involved in muscle protein synthesis and energy generation. Administration of additional doses of valine before exercise (or immediately after) has anti-catabolic effect, protecting the proteins and allowing them to rebuild. It is slightly stimulatory (delays symptoms of fatigue during workout), affecting the level and relations of neurotransmitters. It helps to protect the liver. It stimulates an increase in strength and muscle mass, participates in the reduction of body fat. BCAA, EAA, and other mixtures of amino acid supplementation, protein and protein supplements and carbohydrate-stacks, brings positive results in strength and endurance sports.
Valine deficiency can occur in case of increased energy needs of the body, as the result of stress and too much stress load.
Lysine belongs to the group of 9 essential amino acids delivered into the body from outside (with food or as a supplement) .It is a building substance of protein (the muscle protein). It is available in food of animal origin (meat, dairy products) and vegetable (legumes). It plays an important role in many physiological processes (absorption of calcium, production of enzymes, hormones and antibodies), and arginine is a component of supplements that increase the synthesis of growth hormone (HGH stimulators). In the form of hydroxylysine (a component of collagen) recommended for the treatment of sports injuries, and prevention. In the case of stress and excessive physical and psychological overloads, it is recommended due to the function of lowering cortisol levels. Also it applies in medicine, in the treatment of anxiety and herpes. The share of lysine intake of daily doses of amino acids should not exceed 5.1%. Available for purchase at www.muscle-zone.pl.
In the processes of digestion of protein matter, as a result of decarboxylation of lysine, may be converted into cadaverine (biogenic amine) having a strong toxicity.
Dosage: the lack of a well-defined standard daily intake of lysine. The supplementation dosages regularly used: with arginine 500 mg - 2g (before bedtime) pre- and post-workout optionally with other amino acids.
Alanine is an endogenous amino acid (i.e. having the ability to synthesize the human body other amino acids and pyruvate), building up protein. It has a key role in the transport of nitrogen between the muscles and the liver (i.e. Cahill cycle). It allows to transform glucose in non-sugar compounds. During prolonged exercise it enhances metabolism. It occurs in products of animal origin (meat, dairy, eggs) and vegetable origins (legumes, peas). It is used in the form of amino acid supplements in pre- and post-workout preparations. It complements the BCAA. Increased use of supplements with alanine is required in athletic training when high strength and endurance is required (e.g. weights lifting athletes marathon runners etc.).
Threonine - essential amino acid, or synthesized from food or (and) in the form of supplements. It takes part in the production of new muscle proteins. It is essential for the proper formation of the immune system is maintained in good condition the skin, bones. It affects the normal development of the enamel of teeth and the digestive system by acting positively on the liver and gastric mucosa. It is essential to the proper functioning of the nervous system. On the Polish there are no threonine mono-preparations. Available in the form of blends of amino acids (e.g.the type of EAA) and natural protein supplements.
Deficiency of threonine can cause neurological disorders and increased depression.
Dosage: the lack of standards of daily demand threonine. Doses customarily used in the supplementation.
Histidine is one of the 22 amino acids being part of protein - depending on the source of information it is referred to as "relatively exogenous" or "exogenous". The required dosage of this amino acid is very small, and at the same time it should be added that the intestinal microflora can also play a role in meeting the demand for it.
Histidine is a precursor of carnosine, and therefore dipeptide having antioxidant and buffering qualities. Increasing the dose of carnosine in muscles is an effective way to increase strength and endurance, as well as to accelerate recovery after exercise, thus improving the indicators that are extremely important especially in the case of people being engaged in regular physical activity , including professional athletes.
The number of products containing histidine and available on the market is quite limited. This amino acid is mainly added to some of the supplements used before and/or after exercise, as well as to some of the amino acid supplements. It should be noted, however, that it also occurs naturally in foods rich in protein, and thus primarily in meat, eggs and dairy products, as well as in protein supplements.
Histidine is an amino acid which can be converted in the body into glucose. It also takes part in the synthesis of proteins, including hemoglobin.
Dosage: There are no precise data, but as it has already been hinted above - the required dosage of this amino acid is very small.
Exogenous methionine is an amino acid containing sulphur in its composition. It provides multi metabolism, with the indispensable help of vitamin B6. Participates in the synthesis of phospholipids (e.g. Lecithin), carnitine responsible for transport in the body of long-chain fatty acids, burned in the mitochondria cells (organelles in cells with a separate kernel), along with cystine forms cysteine. It is in the body antioxidant function. Natural source of acquisition of methionine are high-protein foods of animal origin (eggs, meat, fish), vegetable (sesame seeds, grain products). Available in all protein and carbohydrate protein and amino acid supplements such EAA and contain so-called all-day amino acids, supporting the liver preparations and cosmetics supporting the growth and condition of hair, skin and nails.
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