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|Servings: 60 lozenges|
Seeking Health Hydroxo B12 is a dietary supplement containing unmethylated form of vitamin B12 un the form of hydroxocobalamin, which in the organism is easily converted to methylcobalamin (bioactive form of vitamin B12). The preparation is well-tolerated by people who have problems with applying “initially methylated” B-group vitamins.
Vitamin B12 cannot be synthesized by the human organism, but is essential in its proper functioning. Hydroxocobalamin is its natural form, which takes part in the metabolism of energy ingredients (proteins, carbohydrates and fats), influences DNA synthesis, the functioning of the nervous system and due to the fact that it is necessary to the proper creation of red cells, it counteracts anemia. Apart from this, vitamin B12 plays the function of a cofactor of methionine synthase and plays a key role in the conversion of homocysteine to methionine.
Contrary to cyanocobalamin, which contains cyanide molecule in its composition, hydroxocobalamin does not contain any potentially harmful compounds requiring additional processing in order to safely remove it from the organism. Hydroxocobalamin is easily transformed to methylcobalamin, a coenzymatic form of vitamin B12, thanks to which we avoid introducing additional methyl groups to the organism, which is a great alternative to people who are sensitive to methylated B-group vitamins.
Regulation of homocysteinę level
Homocysteine is a sulfuric amino acid, high concentration of which in blood serum – hyperhomocysteinemia is closely related to the increased risk of developing cardiovascular and neurodegenerative diseases, birth defects and cancers. Homocysteine metabolism is a complex mechanism, in which a large role is played by the access of appropriate coenzymes, including vitamin B12, the deficits of which may influence the efficiency of the pathway breaking down homocysteine.
Production of red cells
Cobalamin is essential in the treatment of macrocytic anemia, resulting from deficiency of this vitamin, which leads to synthesis disorders and improper maturation of blood cells in bone marrow. This state is characterized by the occurrence of enormous blood cells along with the drop of their general amount.
The influence on the nervous system
Neurological symptoms of cobalamin very often appear even in case of lack of anemia, especially in case of elderly people. Insufficient level of vitamin B12 largely influences peripheral nerves and in the subsequent stages it may also affect spinal cord, which results in the disorders of psychological functions. The main symptoms most often are “slower thinking”, confusion and memory loss. Interestingly, the levels slightly below optimal values also may cause some disorders in the functioning of the nervous system.
Reduction of fatigue and weariness
According to the available sources, there is a considerable correlation between the intake of vitamin B12 and decreasing fatigue and weariness. Insufficient intake of cobalamin and related symptoms of anemia influence energy drop, lower tolerance of physical effort, fatigue, dyspnea and palpitations.
People prone to vitamin B12 deficiency
Since the main sources of vitamin B12 in the diet are: animal products, including meat, giblets, fish, shellfish, milk, cheese and eggs, people avoiding these products, vegans and vegetarians are burdened with the higher risk of cobalamin deficiency. Vitamin B12 deficiency also appears among patients suffering from absorption disorders in the digestive system (atrophic gastritis, period after stomach resection, bariatric surgery, coeliac syndrome, Crohn’s disease, short bowel syndrome, parasites).
In the risk group there are also children breastfed by mothers suffering from cobalamin deficiency, elderly people and also people abusing alcohol. Bioavailability of vitamin B12 limits regular application of drugs decreasing acidity of gastric juice, proton pump inhibitors and histamine receptors H2 blockers.
The main symptoms of deficiency
Among people with deficits of vitamin B12 there appear mainly symptoms related to the blood-forming system (macrocytic anemia, leucopenia, thrombocytopenia) and neurological system. Among neurological symptoms there are: peripheral neuropathy, drop of muscle tension, apathy, moving back in the development of psychomotor functions and brain tissue decline. Available sources also report on mental symptoms, such as hyperactivity, mood disorders, depression, problems with memory and concentration and psychosis. Other symptoms are gastric system mucous membrane decline, mainly in oral cavity, appetite disorders, anorexia and loss of body mass.
Summing up, Seeking Health Hydroxo B12 is a dietary supplement, which is a great solution for people, who are looking for an unmethylated alternative to a more common form of vitamin B12 – cyanocobalamin. The preparation will work great for all people prone to vitamin B12 deficiency, which most often results from the disorders of its absorption, restrictions in the intake of products of animal origin and alcohol abuse.
According to the most recent data, vitamin B12 supplementation at the dose of 2 mg daily is recommended in case of the appearance of deficiency symptoms, such as increased homocysteine level and neurological problems. Prognosis in case of early diagnosed and well-treated deficiency of vitamin B12 of nutritional origin is good. Delayed treatment may result in permanent damage of the central nervous system. If smaller dose is necessary, the tablet may be broken into smaller pieces.
Seeking Health is a brand which makes sure that the products it produces are characterized by high quality and purity, therefore the majority of their products is free from magnesium stearate, allergens and GMO.
This brand is directed at fighting the causes and not the symptoms, therefore the aim of the company is primarily to help in ensuring optimal work of the digestive system, among others by launching on the market high-class products supporting digestion and regenerating and nourishing the intestines, which consequently improves bioavailability of the substances beneficial to health and increases organism’s resistance to the effect of toxins coming from external environment.
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|per 1 lozenge||amount||%DV|
|Vitamin B12 (as hydroxocobalamin)||2000 mcg||83,333%|
Xylitol, ascorbyl palmitate, silica, and natural cherry flavor.
What is hydroxocobalamin?
Hydroxocobalamin is one of four available forms of vitamin B12. Its advantage over cyanocobalamin consists in the ease of conversion to biologically active forms. It is sometimes used as an antidote in cyanide poisonings, because of high affinity to its ions. This form of vitamin B12 may be an interesting alternative for people, who for various reasons cannot use methyl group donors and want a better-quality supplement than the popular cyanocobalamin.
Vitamin B12 is incredibly important for maintaining proper energy metabolism and high condition of the nervous system. Because of the influence on neurotransmitter synthesis, it contributes to the improvement of mood and psychological functions. It also takes part in DNA synthesis and creatine production by the possibility of increasing the concentration of SAMe. It also helps to maintain homocysteine level in lower values, as it supports its remethylation to methionine. It also plays an important role in blood-forming processes and regeneration of myelin sheaths in neurons.
Hydroxocobalamin in mono-supplements and complex vitamin preparations may be found in the offer of muscle-zone.pl.
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