• Contains unmethylated form of vitamin B12 (hydroxocobalamin)
• Supports proper functioning of the brain
• Takes part in homocysteine metabolism
• Supports healthy pathways of detoxification
• Supports the functions of the nervous system
• Takes part in maintaining psychological functions
• Supports natural immunological processes
• Decreases the feeling of fatigue and weariness
• Plays a role in cell divisions
• Participates in the production of red cells

Seeking Health Hydroxo B12 is a dietary supplement containing unmethylated form of vitamin B12 un the form of hydroxocobalamin, which in the organism is easily converted to methylcobalamin (bioactive form of vitamin B12). The preparation is well-tolerated by people who have problems with applying “initially methylated” B-group vitamins.

Vitamin B12 cannot be synthesized by the human organism, but is essential in its proper functioning. Hydroxocobalamin is its natural form, which takes part in the metabolism of energy ingredients (proteins, carbohydrates and fats), influences DNA synthesis, the functioning of the nervous system and due to the fact that it is necessary to the proper creation of red cells, it counteracts anemia. Apart from this, vitamin B12 plays the function of a cofactor of methionine synthase and plays a key role in the conversion of homocysteine to methionine.

Contrary to cyanocobalamin, which contains cyanide molecule in its composition, hydroxocobalamin does not contain any potentially harmful compounds requiring additional processing in order to safely remove it from the organism. Hydroxocobalamin is easily transformed to methylcobalamin, a coenzymatic form of vitamin B12, thanks to which we avoid introducing additional methyl groups to the organism, which is a great alternative to people who are sensitive to methylated B-group vitamins.

Regulation of homocysteinę level
Homocysteine is a sulfuric amino acid, high concentration of which in blood serum – hyperhomocysteinemia is closely related to the increased risk of developing cardiovascular and neurodegenerative diseases, birth defects and cancers. Homocysteine metabolism is a complex mechanism, in which a large role is played by the access of appropriate coenzymes, including vitamin B12, the deficits of which may influence the efficiency of the pathway breaking down homocysteine.

Production of red cells
Cobalamin is essential in the treatment of macrocytic anemia, resulting from deficiency of this vitamin, which leads to synthesis disorders and improper maturation of blood cells in bone marrow. This state is characterized by the occurrence of enormous blood cells along with the drop of their general amount.

The influence on the nervous system
Neurological symptoms of cobalamin very often appear even in case of lack of anemia, especially in case of elderly people. Insufficient level of vitamin B12 largely influences peripheral nerves and in the subsequent stages it may also affect spinal cord, which results in the disorders of psychological functions. The main symptoms most often are “slower thinking”, confusion and memory loss. Interestingly, the levels slightly below optimal values also may cause some disorders in the functioning of the nervous system.

Reduction of fatigue and weariness
According to the available sources, there is a considerable correlation between the intake of vitamin B12 and decreasing fatigue and weariness. Insufficient intake of cobalamin and related symptoms of anemia influence energy drop, lower tolerance of physical effort, fatigue, dyspnea and palpitations.

People prone to vitamin B12 deficiency
Since the main sources of vitamin B12 in the diet are: animal products, including meat, giblets, fish, shellfish, milk, cheese and eggs, people avoiding these products, vegans and vegetarians are burdened with the higher risk of cobalamin deficiency. Vitamin B12 deficiency also appears among patients suffering from absorption disorders in the digestive system (atrophic gastritis, period after stomach resection, bariatric surgery, coeliac syndrome, Crohn’s disease, short bowel syndrome, parasites).

In the risk group there are also children breastfed by mothers suffering from cobalamin deficiency, elderly people and also people abusing alcohol. Bioavailability of vitamin B12 limits regular application of drugs decreasing acidity of gastric juice, proton pump inhibitors and histamine receptors H2 blockers.

The main symptoms of deficiency
Among people with deficits of vitamin B12 there appear mainly symptoms related to the blood-forming system (macrocytic anemia, leucopenia, thrombocytopenia) and neurological system. Among neurological symptoms there are: peripheral neuropathy, drop of muscle tension, apathy, moving back in the development of psychomotor functions and brain tissue decline. Available sources also report on mental symptoms, such as hyperactivity, mood disorders, depression, problems with memory and concentration and psychosis. Other symptoms are gastric system mucous membrane decline, mainly in oral cavity, appetite disorders, anorexia and loss of body mass.

Summing up, Seeking Health Hydroxo B12 is a dietary supplement, which is a great solution for people, who are looking for an unmethylated alternative to a more common form of vitamin B12 – cyanocobalamin. The preparation will work great for all people prone to vitamin B12 deficiency, which most often results from the disorders of its absorption, restrictions in the intake of products of animal origin and alcohol abuse.