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Aliness Vitamin K2 MK-7 100 μg from Natto + D3 is a dietary supplement containing vitamin D3 and vitamin K2 MK-7 in the patented form of VitaMK7®, obtained through the fermentation process involving Bacillus subtillis natto bacteria cultures, developed by Gnosis. The product is intended to supplement the deficiencies of vitamins D3 and K2 and to support cardiovascular health and the musculoskeletal system.
Vitamin K2 is a group of compounds – menaquinones, which include various subtypes of MK, the most active of which is MK-7. One of the best sources of vitamin K2 MK-7 is natto – a Japanese dish made from fermented soybeans. VitaMK7®, produced in a patented process of bacterial fermentation with the participation of scientifically tested Bacillus subtillis natto strains, is one of the few sources of natural vitamin K2 with a documented action checked by EFSA (European Food Safety Authority).
Vitamin D3 belongs (along with vitamin K2) to the group of fat-soluble vitamins. The active metabolite of vitamin D3 – calcitriol – is a steroid hormone that regulates the calcium-phosphate balance of the body and the expression of genes through the effect on specific VDR nuclear receptors (vitamin D receptors). Vitamin D3 has a multi-directional, positive effect on the health and proper functioning of the skeletal, muscular, nervous and immune systems and plays an important role in the prevention of civilization diseases.
The most well-known function of vitamin D3 is the regulation of calcium-phosphate balance and maintenance of the systemic mineral homeostasis. Calcitriol increases the absorption of calcium from the intestines and inhibits its excretion in the urine. Too low concentration of this element in the blood results in an increased release of calcium from the bones.
Calcium has a number of extremely important physiological functions, including the involvement in hormonal regulation and neurotransmission; it is necessary for muscle contraction, plays a role of building material – it is necessary for the proper mineralization of the skeleton. Almost 99% of calcium in the bones is bound in the form of apatite.
In addition to the regulation of calcium-phosphate metabolism, vitamin D3 affects the metabolism of bone tissue, directly affecting individual populations of bone cells. By regulating gene expression, it plays an important role in osteogenesis, bone cell differentiation, maintenance of balance between resorption and bone formation, and synthesis of proteins by osteoblasts that are necessary for optimal bone mineralization.
Vitamin D3 affects the proper functioning of the muscles, as evidenced by the presence of VDR receptors in smooth and striated muscle cells. It positively influences the synthesis of muscle proteins and has anti-inflammatory properties, thanks to which it supports post-workout regeneration and may protect against injuries.
Synergism of the action of vitamins D3 and K2
Vitamins D and K cooperate in the regulation of calcium-phosphate metabolism and bone tissue metabolism. Figuratively speaking, vitamin D3 increases the absorption of calcium, while vitamin K2 allows transport of calcium to the bone, protecting against the undesirable deposition of this element, for example in the arteries (which poses a threat to the cardiovascular system) and joints.
Vitamin K2 affects the activity of osteocalcin, a bone matrix protein, which in its active form is able to incorporate calcium ions into the bone tissue. In addition, vitamin K2 stimulates the SXR receptors (steroid and xenobiotic receptor), thus contributing to the regulation of the expression of numerous genes encoding bone matrix proteins.
Common vitamin D deficiencies
Vitamin D3 is naturally produced from the 7-dehydrocholesterol present in the skin under the influence of UV-B radiation. Common deficiencies of this vitamin result from ineffective skin synthesis caused by insufficient exposure of inadequately large skin surface to the sun, the use of sunscreens, air pollution and geographical location, which prevents optimal sun exposure. Due to the numerous health consequences of long-term vitamin D3 deficiency, it should be supplemented with a high-quality preparation.
To sum up, Aliness Vitamin K2 MK-7 100 μg from Natto + D3 is a preparation recommended for regular supplementation to prevent deficiencies of vitamins D3 and K2, support musculoskeletal and cardiovascular health, strengthen immunity, in autumn and winter, for elderly people and athletes, and to prevent civilization diseases.
The product is best taken with a meal containing fat.
For strengthening the bones, in addition to supplementation of vitamins D3 and K2, a diet containing sources of calcium and phosphates is also necessary.
Vitamins D3 and K2 are worth combining with the supplementation of omega-3 fatty acids and vitamin E.
Aliness is a Polish brand owned by Medicaline. The company has advanced development and research facilities and meets the demanding European Standards of Production and Storage based on the pharmaceutical standard GMP and HACCP. A team of experienced specialists supervises the quality of manufactured dietary supplements. The company uses only the highest quality certified raw materials, often occurring in patented forms.
Aliness cooperates with the research laboratories accredited by the Main Pharmaceutical Inspectorate - SGS Poland and J.S. Hamilton Poland S.A., and also with the National Institute of Medicines, responsible for quality and safety control in research and development. Many Aliness products have an ecological certificate, which is a guarantee of the lack of use of artificial fertilizers, pesticides and chemical plant protection products at all stages of the production of the raw material.
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Vitamin K exists in the triad of vitamins: menaquinone (vitamin. K1), menadione (vitamin. K2) and menadione (vitamin. K3), soluble in fat. It is produced by bacteria in the human colon. Natural sources of vitamin. K are: eggs, kale, cauliflower, cabbage, meat, milk, lettuce, spinach, fish oil and liver. The synthetic form is administered to newborns, to reduce the sterility of the gastrointestinal tract. Used as a antihaemorrhagic, due to its participation in the process of prothrombin. Increases antibacterial and antifungal immunity. Prevents abundant bleeding during menstruation of women.
Vitamin K deficiency causes external bleeding and ecchymosis on skin, decreased prothrombin synthesis in the liver (especially while taking antibiotics and sulfanilamide).
Vitamin D belongs to fat soluble vitamins, occurs in three forms: calciferol (vitamin D1) ergocalciferol (vitamin D2) and cholecalciferol (vitamin D3), it is formed under the action of sunlight for at least 15 minutes per day. In the absence of sunlight it should be administered in the diet in the form of fish oil (Vitamin A + D3) and fish oils. It is responsible for the absorption of calcium and phosphorus. It is the building substance of bone tissue particularly necessary during pregnancy, childhood, and for athletes. It is a component of dietary supplements and nutrients among competetive athletes. Deficiency of vitamin D causes children growth inhibition, and rickets.
For adults - deficiency causes osteomalacia.
Excess of vitamin D causes headaches, alopecia, nausea, drowsiness, blurred vision, pain in the long bones, the deposition of calcium deposits.
Dosage: 400 IU units during the day.
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