Since 2005
You are currently:
Choose language:
Need help?
Leave message
Choose language:
Select currency: $ £
Since 2005
en
USD
Order:56.00 $113.00 $169.00 $225.00 $282.00 $
Shipping:-3.00 $-6.00 $-8.00 $-11.00 $-14.00 $
0 0.00 $
Since 2005  sales@mz-store.com  +1 844-530-3647
Since 2005
Add to Cart
Optimized Folate Optimized Folate 1000mcg 100 tab.
Life Extension
15.57 $

Optimized Folate 1000mcg 100 tab.

Servings: 1000mcg 100 tab.

All variants:

1-2
Location:
EU Stock
Availability:
Medium amount
Working days
from the dispatch
Minimum expiration date:
2021-10
For free shipping is missing: 80.00 $
15.57 $With VAT
0.16 $ / serving

From 3 units only 15.26 $ /Units. -2%

1 Units.
Add to Cart

Customer Service

(mon.-fri 900-1700

You have got questions about the product

Description
  • Recommended for pregnant women
  • Contains bioactive methylfolate
  • Improves methylation processes
  • Important haematopoietic factor
  • Regulates the level of homocysteine
  • Beneficial for mental health
  • Supports the immune system
  • Reduces the feeling of fatigue
  • Participates in the process of cell division
  • Maintains normal metabolism

Life Extension Optimized Folate is a highest quality dietary supplement with optimised folate, i.e. a bioactive form of folic acid 5-MTHF (5methyltetrahydrofolate) in the amount of 5000 mcg in one vegetarian tablet.

Bioactive folate ensures maximum support both for the health of the cardiovascular system and for cognitive functions. It is recommended to supplement 5-MTHF together with methylcobalamin (B12) and vitamin B6.

Folate (pteroylglutamate) - also called folic acid, vitamin B9 or B11, synthesised by intestinal bacteria; its bioactive form is tetrahydrofolate (THF) which performs the function of a coenzyme in the reactions of the transfer of active monocarbon groups (methyl, formyl, formimino, methylene, methenyl groups).

Why is "ordinary" folic acid not the right one?
Commonly used folic acid, a component of many dietary supplement, has very limited effect on many people, as not every organism is able of converting the compound into the biologically active form 5-MTHF, which is caused by a genetic deficiency of enzymes that enable the conversion.

That situation has very bad consequences for health and may lead to, among other things, a pathologically high level of homocysteine and cognitive function disorders. Moreover, a link has been found between folic acid supplementation and increased incidence of rectal, breast and prostate cancer as well as autism in children.

Homocysteine as a risk factor
Homocysteine is a sulphur-containing amino acid which occurs in the human organism as a result of demethylation of the amino acid called methionine. It is currently thought to be an independent risk factor in the development of atherosclerosis, the coronary heart disease, heart attacks and thrombotic disorders.

The above-described changes are caused by impeded 5-MTHF synthesis by methylenetetrahydrofolate reductase which leads to functional folate deficiency and, in turn, to impeded remethylation of homocysteine to methionine.

5-MTHF (5methyltetrahydrofolate) - also called levomefolic acid; it is a biologically active form of folic acid and the main source of tetrahydrofolates for tissues. It plays a unique role in remethylation of homocysteine to methionine. The reaction is catalysed by methionine synthase, which is an enzyme dependent on methylcobalamin (vitamin B12). The consequence of the reaction mentioned above is the production of methionine, which reduces the level of homocysteine in the system, preventing the development of circulatory system diseases.

Biological functions of folates
Folate is one of haematopoietic factors which determine the normal process of erythropoiesis, i.e. the process of erythrocyte multiplication and differentiation (red blood cells) from stem cells in the bone marrow of flat bones and long bone epiphyses. Moreover, it has an important function in DNA synthesis, cysteine metabolism, synthesis of essential neurotransmitters (dopamine, norepinephrine and serotonin) and endorphins.

Deficiency consequences
Folate deficiencies lead to megaloblastic anaemia, which occurs as a result of impeded DNA synthesis that brings about blood cell maturation disorders. In addition, some disorders of the central nervous system may occur, which also needs the vitamin for the normal functioning - it has been demonstrated that about 30% of patients with mental disorders have a low concentration of folate in the blood.

Recommended for pregnant women
Folate supplementation is very important for pregnant women, as it is responsible for the normal development of the nervous system in a growing foetus. Folate supplementation before conception in the amount of 400 mcg per day can significantly reduce the risk of spina bifida and other defects of the foetus' neural tube.

To sum up, Life Extension Optimized Folate is an obligatory product for people with methylation disorders, an increased level of homocysteine and for mothers-to-be. For best results, it should go together with methylcobalamin and vitamin B6 supplementation. 

Directions for use
Manufacturer
Reviews (0)

Composition

Container size: 100 vegetarian tabletsServing size: 1 tabletServings per container: 100
per 1 tabletamount%DV
Folate [as (6S)-5-Methyltetrahydrofolic acid, glucosamine salt]1000 mcg250%

Other ingrednients

microcrystalline cellulose, dicalcium phosphate, croscarmellose sodium, silica, vegetable stearate, stearic acid.

Similar products
Best to combine with
Aliness
8.42 $

High dose of zinc in three organic forms of high bioavailability. Powerful support for immunomodulation.

Buy
Apollo's Hegemony
14.51 $
(1)

Pure trimethylglycine (TMG) powder. Support for methylation processes and psychophysical condition.

Buy
Now Foods
20.85 $

Supplement containing extract of milk thistle. Supports liver and removes toxins.

Buy
Nordic Naturals
27.71 $

Supplement with omega-3 acids designed for children. Liquid formula with a pleasant fruity flavour.

Buy
Olimp
12.93 $

The supplement supports a healthy cardiovascular and motor system.

Buy
Olimp
3.43 $

Dietary supplement of an extract of garlic bulbs. It protects the heart and circulatory system, kills bacteria.

Buy

Salt

Information

Salt (sodium chloride, or table salt), natural source of electrolytes (chlorine and potassium), regulating water and electrolyte and acid-base balance of the body, affecting the nervous system and blood pressure. Sodium is an essential element for the proper growth. The proper dose of salt prevents overheating of the body and solar stroke. It provides the proper functioning of muscles and nerves the body. Chlorine in combination with sodium, is involved in the digestive process and maintains acid-base balance in the body, as antitoxin removes toxic products of metabolism in the liver. Salt is a flavour component and preservative of many foods, nutritional supplements and mixtures of electrolytes, available at www.muscle-zone.pl

Dosage: no specific standards of consumption, used so as to provide sufficient amount of electrolytes to the body (sodium and chloride).

 

Latest on blog

#19 Supplements review – Apollo’s Hegemony Magnesium Malate

#19 Supplements review – Apollo’s Hegemony Magnesium Malate

It’s hard to say anything new about magnesium, due to how intensively its properties are exploited by the modern supplementation and pharmacological...

Read more
Herbs for stress – a natural way to soothe nerves

Herbs for stress – a natural way to soothe nerves

Stress is an integral part of our lives. Constant hurry, excess of duties, fatigue, new challenges, the fast pace of life, work pressure – these are just a...

Read more
How to treat cystitis? Recommended herbs

How to treat cystitis? Recommended herbs

One of the most troublesome infections that practically all of us may encounter is cystitis, which is called also an urinary tract infection. This disease is most...

Read more
Kidney stones

Kidney stones

It usually develops in people between thirty and fifty years old, more often touching men than women. At the initial stage, it gives practically no symptoms, and...

Read more
Three methods that will make us feel better with ourselves

Three methods that will make us feel better with ourselves

Lack of acceptance of our own body is a problem for thousands of women. And although we can often hear that this is not the biggest drama that could happen to us,...

Read more
#18 Supplements review – Apollo’s Hegemony  Ultra Fish Oil

#18 Supplements review – Apollo’s Hegemony Ultra Fish Oil

The fight for fats in modern diets, fortunately, seems to bring positive results. Low-fat diets, very popular a few years ago, are becoming more and more...

Read more

Sign up for our newsletter
And receive coupons, news, special offers and much more!

Customer service

MZCatalog - recommended dietitians

MZCatalog - recommended trainers

MZCatalog - recommended clubs

Supps4You LLC
Unit 3 Enterprise Court, Farfield Park Rotherham S63 5DB
sales@mz-store.com +44 7767803657