Blog us   | en | USD
0 0.00 $
 sales@mz-store.com  +1 844-530-3647
Since 2005
Notify me of availability
L-5-MTHF 1000mcg L-5-MTHF 1000mcg 60 caps.
Seeking Health
17.95 $
Location: eu

L-5-MTHF 1000mcg 60 caps.

From 3 units only: 17.60 $ / Units. -2%

Shipping weight: 150g
No gluten
No GMO
Vegetarian

As an alternative, we recommend:

Methyl B12 + 5-MTHF 60 caps.
Methyl B12 + 5-MTHF 60 caps.
Apollo's Hegemony
11.95 $
Compare composition
17.95 $ With VAT
0.30 $ / serving
We can let you know you when the product will be available again
Save
Description
  • Supports effective methylation processes in body
  • Reduces risk of neural tube defects in foetuses
  • Source of folate in highly assimilable form
  • Reduces damage caused by DNA oxidation
  • Participates in homocysteine metabolism
  • Enhances blood flow
  • Exerts neuroprotective effect
  • Antidepressant properties

Seeking Health L-5-MTHF is a dietary supplement providing the organism with 1000 mcg of pure L-methylfolate – a source of vitamin B9 in the form of an active coenzyme.

The fantastic assimilability of the form stems from the fact that, unlike other forms, it does not require any additional metabolic processes for the organism to utilise it practically entirely. It is particularly important in the case of people with high demand for folates, including pregnant women or people suffering from a mutation of the enzyme MTHFR, which is essential in the reduction of a substrate of folic acid metabolism in the organism (5,10-CH2-THF) to L-methylfolate, whose metabolic activity in that case can drop by even 70%.

The most important role of 5-MTHF in the organism is the participation in methylation processes. It is a methyl group donor in the conversion of homocysteine to methionine (as a by-product, SAMe is created – S-adenosyl methionine, which is the main methyl group donor in systemic processes).

Research has demonstrated versatile positive effects of folates on the nervous system. Their neuroprotective properties have been discovered regarding mainly lead and dexamethasone poisonings as well as high homocysteine levels. However, the most interesting fact is the relationship between those compounds and depressive disorders. Tests clearly show that reduced blood folate levels increase the risk of developing depression. A study managed to foresee a depressive episode directly on the basis of reduced folate levels in the blood serum which occurred before the episode. It was also demonstrated that the time needed for fluoxetine, an antidepressant, to start working is longer in the above-described systemic conditions. Further research on that subject demonstrated a positive synergic effect of folates (in the dosage of 500 mcg) with antidepressant drugs of the groups SSRI and TCA, as well as a reduction of resistance to those drug groups. The effect was much more prominent among groups with naturally low folate levels and even more obvious in the case of women.

Another function of folates is their antioxidant ability regarding the DNA thanks to the fact that it has a 4-hydroxypyrimidine element. Their proper levels in the circulation prevent excessive homocysteine levels, which can damage the DNA by oxidising it. The effect was documented in a test on the basis of the marker 8-OHdG, whose amount decreased in the case of interventional folate supplementation in the doses of 400-800 mcg.

A well-known benefit of folate supplementation is their ability to reduce the risk of neurological complications in pregnancy. The right dosage of folates (according to research, 800 mcg) reduces the risk of neural tube defects to 0.

It is also worth mentioning what effects they have on the circulatory system. Folate supplementation improves the levels of BH4 and nitric oxide while reducing homocysteine levels. All those changes are crucial for improving the permeability of blood vessels.

To sum up, Seeking Health L-5-MTHF is an excellent choice if your goal is interventional or long-lasting folate supplementation. The form of L-methylfolate is the best one available in the case of those compounds because of the lack of the need to metabolise it further in the organism (for comparison, regular folic acid has to undergo four subsequent reactions in order to turn into L-methylfolate, and with each reaction, part of the substance is lost). Folates themselves have a great deal to offer, especially in terms of maintaining the right condition of the nervous system, eliminating free radicals, and the safety for pregnant women.

Directions for use
Manufacturer
Reviews (0)

Composition

Container size: 60 capsulesServing size: 1 capsuleServings per container: 60
per portion (1 capsule)amount%DV
Folate (as Quatrefolic® (6S)-5-methyltetrahydrofolate, glucosamine salt)1000 mcg425%

Other ingrednients

Microcrystalline cellulose, HPMC (capsule), ascorbyl palmitate, L-leucine, and silica.

Similar products
Best to combine with

Latest on blog

MIND diet – will improve memory and reduce the risk of Alzheimer’s disease

MIND diet – will improve memory and reduce the risk of Alzheimer’s disease

Alzheimer’s disease is nowadays one of the most common neurodegenerative diseases. It results in loss of nerve cells in the brain, leading to memory...

Read more

Paleo diet – what does it consist of? What should we not eat on this diet?

Paleo diet – what does it consist of? What should we not eat on this diet?

The Paleo diet aims to imitate as closely as possible the diet of the Paleolithic man. Paleo diet – we eat lean meat and fishPaleo diet – eggs, seeds...

Read more

Psyllium – for digestive problems, coughs, and wounds

Psyllium – for digestive problems, coughs, and wounds

As a medicinal plant, Psyllium has been known since ancient times (both in Europe and China). For years they have also been used in natural medicine. Due to their...

Read more

Donuts – how many calories do they have? How to get rid of donut calories?

Donuts – how many calories do they have? How to get rid of donut calories?

Donuts are known almost all over the world and depending on the region they may differ in filling (or lack thereof) and how they are called. Although they were...

Read more

Vitamin E – more than the vitamin

Vitamin E – more than the vitamin

Vitamin E is actually not a single, specific substance, but rather a group of chemical compounds. The demand for it depends on age and gender. Young children need...

Read more

3 dietary changes your body will thank you for

3 dietary changes your body will thank you for

Replace white bread with whole-grain breadChoose brown rice, pasta, and groatsReplace sweets with nutsSummary Replace white bread with whole-grain bread Whole...

Read more

Sign up for our newsletter
And receive coupons, news, special offers and much more!

Customer service

MZCatalog - recommended dietitians
MZCatalog - recommended trainers
MZCatalog - recommended clubs
Trustpilot
Also check out our excellent ratings on  Opineo
Supps4You LLC
Unit 3 Enterprise Court, Farfield Park Rotherham S63 5DB
sales@mz-store.com +44 7767803657