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The main active substance of the preparation is juglone. The natural compound belongs to the group of strong antiparasitic agents; moreover, it also exhibits antiseptic, chelating (it binds even heavy metals deposited in the organism and facilitates their removal) and antidiarrheal effects. It is worth mentioning that juglone is recommended for people with diabetes, and black walnut hulls and fruit can contribute to the lowering of the cholesterol level.
Black walnut (Juglans nigra L.) – a tree species of the walnut family. It occurs naturally in North America, in the central and eastern parts of the United States. The most important active compounds found in it are tannins, flavonoids (antioxidants), and juglone, a substance with a strong antimicrobial, antiparasitic and antifungal effect.
Black walnut extracts can alleviate inflammations in the digestive system, the oral cavity, as well as dermatitis and inflammations of mucous membranes. Tannins present in it have an antidiarrheal effect and can eliminate pains and swelling. Apart from that, the plant contains essential oils, iron, cobalt, manganese, iodine, vitamins C, B1 and B2, and ß-carotene.
Juglone (5-hydroxy-1,4-naphthalenedione) belongs to phenolic compounds and occurs in various walnut tissues, including the hull. Having permeated into the soil, the substance makes other plants around the walnut tree develop weakly and eventually die. That property is what drew the interest of scientists and convinced them to take a closer look at the substance.
Juglone is one of the strongest naturally occurring antiseptic compounds in the world and it is applied in medicine as an antimicrobial, antifungal and antiviral agent. It is also used against intestinal parasites, such as pinworms and Ascaris lumbricoides, or in treating dermatitis and mycoses (Candida).
Juglone prevents the development of bacteria that cause tooth decay (Streptococcus mutans and Streptococcus sanguis) and pathogens of the periodontium (Porphyromonas gingivalis and Prevotella intermedia). As a ribonuclease inhibitor, it inhibits HIV replication.
Scientific tests have provided much evidence that juglone can be used in the future as a drug in cancer therapies. It exhibits a cytotoxic and genotoxic effect on many types of cancer cells. It has been documented that juglone is a strong inhibitor of Pin1 isomerase, and blocking its activity causes the inhibition of cell division and the apoptosis of many types of cancer cells. Other studies demonstrated that it has an inhibitory effect on the production of azoxymethane, a factor that causes intestinal cancer in rats.
Black walnut hull extracts contain polyphenolic compounds, considered to be one of the strongest types of antioxidants. Antioxidants neutralise the harmful activity of free radicals that can be a reason of faster, premature aging of the organism, immune system disorders, cardiovascular system diseases, and cancers. Thanks to xanthine oxidase inhibition, the extracts can not only sweep free radicals away, but also decrease their formation. Results of some studies also show that polyphenols strongly stimulate burning fat reserves, facilitating the reduction of excess fat tissue.
Supplementation with black walnut hull extracts can be very beneficial for health. The content of iodine can help to regulate the functioning of the thyroid gland and thyroid hormone secretion. Antioxidants exhibit strong neuro- and cardioprotective properties. The content of tannins, which are astringents, is believed to have a beneficial effect on mucous membranes in the digestive system, prevent diarrhoea and reduce excessive sweating.
To sum up, Now Foods Black Walnut Hulls is a dietary supplement, recommended particularly to people susceptible to parasitic infestations and infections with live pathogens. It can be successfully used as help in treating mycoses and oral cavity diseases caused by bacterial infections, such as tooth decay. Thanks to the content of strong antioxidants, it can also be a powerful tool in preventing diseases of affluence and neurodegenerative disorders.
Take precautions when using the supplement with other medicines because it may cause the interaction with medications and cause reduced absorption. It is recommended to use the product for at least one hour after taking the drug, to reduce the risk of drugs interactions.
Now Foods is a company with years of experience in the industry that offers a wide range of nutrients and dietary supplements. Brand is known for its high-quality products designed for hair and nails and supplements supporting the immune system. The offer includes the antioxidant supplements, antibacterial supplements, reducing appetite supplements, products supporting the reduction of body fat and improving digestion. All products are made from natural ingredients.
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|per portion (1 capsule)||amount||%DV|
|Black Walnut (Juglans nigra) (Hulls)||500mg||*|
Gelatin (capsule), Magnesium Stearate (vegetable source) and Silica.
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