This is a simple and extremely useful tool (a shipping cost progressive bar) that allows you to control the distance that separates from the next shipping discount threshold.
This is a simple and extremely useful tool (a shipping cost progressive bar) that allows you to control the distance that separates from free delivery.
Confirm or change your preferred country of delivery, language or currency. If you do this when logged in, your preferences will be remembered on your MZAccount. You can change them at any time by clicking the arrow at the top of the page.
Your location affects the final order price. It may vary depending on the amount of VAT rate applicable at your current location.
default stock for current location
From 3 units only: 11.62 € / Units. -2%
Seeking Health Vitamin D3 is a dietary supplement with a high dose of vegetarian-source vitamin D3 (5000 IU). Such a large dose of the active substance helps fight effectively deficiency of this vitamin in the body. Even though it is produced naturally in the skin by sunlight, this process is insufficient in our climate. The vitamin in the form of cholecalciferol in this dietary supplement supports healthy function of the whole body.
Mechanism of action of cholecalciferol
It is not without reason that vitamin D3 (cholecalciferol) is considered a prohormone. It has been shown that after absorption into the blood it is converted in the liver and kidneys where it is activated. Its active form exerts a biological effect on the body by binding to vitamin D receptor (VDR).
Vitamin for healthy bones
Vitamin D3 is an important element responsible for normal bone structure. It helps build them properly by a double mechanism of action.
Cholecalciferol regulates levels of many enzymes in the body. They include aromatase which converts testosterone in oestrogen. Proper levels of vitamin D3 and aromatase help maintain normal bone density.
In addition, the active form of the vitamin binds to the vitamin D receptor and has thus an impact on bone cell proliferation and bone mineralisation. It supports proper uptake of calcium and phosphorous ions from the bloodstream into bones and facilitates their incorporation. It is also responsible for healthy teeth.
Impact on the endocrine system
Vitamin D is very similar structurally to steroid hormones. Both they and vitamin D are based on cholesterol. Normal blood cholecalciferol levels are responsible for normal function of the endocrine system in the body.
It has been observed that individuals with its deficiency have frequently insufficient testosterone levels. Replenishing levels of this vitamin helps restore normal levels of androgenic hormones. This is manifested by improved libido, high-quality semen production and general well-being in men.
A positive effect of vitamin D has been demonstrated on parathyroid hormones and oestrogen.
For a healthy nervous system
The nervous system contains an enzyme activating vitamin D3. Owing to that, the vitamin exerts a positive impact on its function. The greatest amounts of cholecalciferol were observed in the hypothalamus and dopaminergic neurons of the grey matter. The main function of the vitamin is to protect nerve cells from harmful factors.
One of them is excitotoxicity, namely excessive destructive neuronal excitability which is caused by too high concentration of calcium ions in the blood. Consequently, vitamin D3 shows neuroprotective properties.
Studies confirm that cholecalciferol deficiency is associated with increased degeneration of neurolemma. This sheath is a structure which surrounds the nerve cell and thus ensures normal neurotransmission. Its degeneration can be observed in individuals with multiple sclerosis. What is more, stressors, which also damage the nervous system, contributes to the development of Alzheimer’s and Parkinson’s disease. Because of that, adequate levels of this vitamin in the body help reduce the incidence of these diseases.
Vitamin D3 allows you also to get normal depth of sleep. This results in efficient regeneration of the nerve tissue which helps maximise the effectiveness of its function. As a consequence, we can have a better mood and improved cognitive functions.
It has been demonstrated that individuals with depression have low blood vitamin D3 levels.
Protection from diseases
Healthy vitamin D3 levels support the body in fighting against diseases. It is due to the fact that the function of immune cells is improved. Because of that, the body combats pathogens more efficiently.
It has been shown that cholecalciferol improves the function of monocytes and thus reduces their excessive adhesion to blood vessel walls. This reduces the incidence of cardiovascular diseases.
By stimulating the immune system into more efficient function and affecting many bodily processes, vitamin D3 reduces the likelihood of some cancer types.
For a healthy heart
Vitamin D3 deficiency is associated with cardiovascular diseases. It helps protect the heart and blood vessels from too high blood pressure. The vitamin decreases therefore the secretion of renin which belongs to the renin–angiotensin–aldosterone system responsible for regulating blood pressure. A decrease in renin secretion causes a series of events which leads to a drop in blood pressure.
By transferring calcium from the bloodstream into proper tissues, cholecalciferol prevents its excessive deposition in blood vessel walls. As a result, it reduces calcification of blood vessels and contributes to their normal structure. It helps also reduce the growth of atherosclerotic plaque, the main factor in the development of ischaemic heart disease.
Improves carbohydrate balance
Vitamin D3 sensitises the body to insulin. As a consequence, it helps utilise properly carbohydrates found in the blood. This reduces the incidence of hyperglycaemia, which is dangerous especially for diabetics. In addition, cholecalciferol contributes to normal utilisation of glucose, thereby inhibiting the development of diabetes and providing effective support for obese individuals with insulin resistance.
Increased energy levels
Even though VDRs are not found skeletal muscle cells, vitamin D3 affects directly the effectiveness of muscle function. This is due to improved calcium balance and its overall impact on bodily function. It has been proven that properties of this vitamin promotes recovery after injuries.
Effect on pregnant women
It has been observed that blood vitamin D levels in pregnant and breastfeeding women are significantly decreased. This is due to increased requirements for this vitamin because it has a vital function in child development. Cholecalciferol is important especially during the first trimester of pregnancy.
Seeking Health Vitamin D3 is a dietary supplement recommended mainly to individuals affected with this vitamin deficiency. Even though the human body has the ability to synthesise cholecalciferol, the moderate climate does not help maintain its normal production. Because of that, this vitamin deficiency may affect almost everyone. A high-risk group comprises pregnant women, the elderly and physically active individuals. Normal levels of vitamin D3 metabolites are responsible for healthy function of the whole body, especially the cardiovascular, motor and immune system.
Take 1 capsule with food any time of day or as directed by your healthcare professional.
Seeking Health is a brand which makes sure that the products it produces are characterized by high quality and purity, therefore the majority of their products is free from magnesium stearate, allergens and GMO.
This brand is directed at fighting the causes and not the symptoms, therefore the aim of the company is primarily to help in ensuring optimal work of the digestive system, among others by launching on the market high-class products supporting digestion and regenerating and nourishing the intestines, which consequently improves bioavailability of the substances beneficial to health and increases organism’s resistance to the effect of toxins coming from external environment.
200 characters left for the review to be rated.
Latest on blog
Alzheimer’s disease is nowadays one of the most common neurodegenerative diseases. It results in loss of nerve cells in the brain, leading to memory...
The Paleo diet aims to imitate as closely as possible the diet of the Paleolithic man. Paleo diet – we eat lean meat and fishPaleo diet – eggs, seeds...
As a medicinal plant, Psyllium has been known since ancient times (both in Europe and China). For years they have also been used in natural medicine. Due to their...
Donuts are known almost all over the world and depending on the region they may differ in filling (or lack thereof) and how they are called. Although they were...
Vitamin E is actually not a single, specific substance, but rather a group of chemical compounds. The demand for it depends on age and gender. Young children need...